Additional file 1 of Monocytes reprogrammed by tumor microparticle vaccine inhibit tumorigenesis and tumor development

Abstract

Additional file 1: Fig. S1. Intramuscular injection of B16-MPs inhibited tumorigenesis of B16-F10 melanoma. Fig. S2. Intramuscular inoculation of MPs from CT26 colon carcinoma cells rather than those from H22 hepatocarcinoma cells led to prevention of CT26 tumor growth. Fig. S3. T-MPs as a tumor vaccine presented a good safety. Fig. S4. B lymphocytes and T lymphocytes in BALB/c mice don't endocytose T-MPs. Fig. S5. T-MPs are mainly endocytosed by monocytes and macrophages in C57BL/6 mice. Fig. S6. T-MPs treatment doesn't cause the proliferation of moDCs in the dLN. Fig. S7. DNAs and RNAs were isolated from T-MPs