False-negative coagulation factor activity results due to the presence of antiphospholipid antibodies in a case of autoimmune hemolytic anemia

An 88-year-old female was admitted with autoimmune hemolytic anemia (AIHA). Coagulation test revealed severe prolongation of activated partial thromboplastin time (APTT). APTT cross-mixing test with patient plasma and normal plasma demonstrated an inhibitory pattern. Several intrinsic coagulation factor activities, particularly factor IX, showed remarkable decreases, and the inhibitor titers for coagulation factors VIII and IX were elevated. Although AIHA with existing antiphospholipid (aPL) antibodies was diagnosed initially, purpura developed on extremities intermittently during the clinical course. Considering the possibility of coexisting acquired hemophilia, APTT cross-mixing test with patient’s plasma and equal amount of the recombinant factor VIII product instead of normal plasma was performed. The APTT value on equal mixing samples with patient plasma and recombinant factor VIII product was decreased to within the normal range, and coagulation factor IX activity was restored. These results indicate that the recombinant factor VIII product had a neutralizing effect on aPL antibodies. We concluded that recombinant factor VIII product may lead to the repair of incorrect results from the APTT-dependent diagnostic system in the presence of aPL antibodies

瀬戸内国際芸術祭2013 沙弥島アートプロジェクト by 神戸芸術工科大学

本稿は、瀬戸内国際芸術祭2013 春の部（2013年3月20日[春分の日]～4月21日[日]）の一環として参加した「沙弥島アートプロジェクト by 神戸芸術工科大学」で行われた全ての活動について、成果物の画像を交えながらその内容を述べたものである。成果物として挙げられるのは、次の4つ、①香川県坂出市沙弥島内3カ所（西ノ浜、ナカンダ浜、旧沙弥小中学校）を舞台にした本学の教員（助手・実習助手含む）6名による作品展示・建築作品の公開、②準備期間中に行った地元の子供・親子を対象にしたワークショップ、③会期中に行った一般客及び地元住人を対象にしたイベント、④大学院の選択科目のひとつである大学院総合プロジェクト「沙弥島アートプロジェクト」において、担当教員の指導のもと、学生が行ったポスターや周辺地図などの印刷物およびスタッフ用パーカーなどのグッズ企画・制作である。This report assesses all the activities carried out in ‘Shamijima Art Project by Kobe Design University’ which was held as a part of Setouchi Triennale 2013 Spring term (20th March and 21st April 2013), together with the images of the project outcomes. The following four types of work have been completed in the project; ① Works of art and architecture created by six teachers of KDU(including assistants and a research assistant) in three different venues (Nishinohama Beach, Nakandahama Beach and Fomer-Shami Elementary and Junior High School), ②Workshops for the local people held in the preparation period, ③ Events for both the local and general visitors during the Triennale period, and ④ Poster, map and other graphic design works and goods productions such as staff costume created by students under the supervision in the one of the Kobe Design University graduate school’s optional subjects which is also called ‘Shamijima Art Project’

アートプロジェクトによるコミュニティ生成/瀬戸内国際芸術祭2013、沙弥島アートプロジェクトの実践による研究

2013 年、第2 回「瀬戸内国際芸術祭2013」が開催され、本学でも香川県坂出市沙弥島を会場とする「沙弥島アートプロジェクト by 神戸芸術工科大学」として参加した。このプロジェクトは2013 年3 月20 日から4 月21 日を会期としたもので、全容は昨年の紀要「芸術工学2013」において報告したが、沙弥島を対象とした研究は継続して行われ、秋季には「沙弥島・あの感動を再び」と題して、独自の展覧会を行った。プロジェクトは2012 年度と13 年度をまたいで実践されることになったが、2013 年度共同研究としての位置づけとしては、春季開催中の会場運営、夏期芸術祭期間の他会場での開催プロジェクトとの比較考察、秋季展覧会の企画・実践を担っている。また、この2013 年の成果をもとに沙弥島でのプロジェクトは2014 年度も継続することが決定している。‘Shamijima Art Project by Kobe Design University’ was held as a part of Setouchi Triennale 2013 Spring term (20th March to 21st April 2013). Complete works of the spring term project were reported on bulletin of last year ‘2013’. Since then the project was continued under the subvention of the University.In the summer term of the Trinnale, some member of research inspect the another area of Setouchi and consider the way of community formation by arts or architectural design.In autumn, we planned a second exhibition and workshop titled ‘we remember the Shamijima’. The main subject of the show is retrospect of spring term project. But then two particular programs are executed. ‘Possible futures Sakaide’ show the fictional cityscape. These works are represented by high-school students of Sakaide city. At the workshop for children, salt and shell of Shami-beach is the matter.At present, Shamijima Art Project progress to 2014’s new program