479 research outputs found

    Opening Size Effects on Airflow Pattern and Airflow Rate of a Naturally Ventilated Dairy Building-A CFD Study

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    Airflow inside naturally ventilated dairy (NVD) buildings is highly variable and difficult to understand due to the lack of precious measuring techniques with the existing methods. Computational fluid dynamics (CFD) was applied to investigate the effect of different seasonal opening combinations of an NVD building on airflow patterns and airflow rate inside the NVD building as an alternative to full scale and scale model experiments. ANSYS 2019R2 was used for creating model geometry, meshing, and simulation. Eight ventilation opening combinations and 10 different reference air velocities were used for the series of simulation. The data measured in a large boundary layer wind tunnel using a 1:100 scale model of the NVD building was used for CFD model validation. The results show that CFD using standardk-epsilon turbulence model was capable of simulating airflow in and outside of the NVD building. Airflow patterns were different for different opening scenarios at the same external wind speed, which may affect cow comfort and gaseous emissions. Guiding inlet air by controlling openings may ensure animal comfort and minimize emissions. Non-isothermal and transient simulations of NVD buildings should be carried out for better understanding of airflow patterns

    CFD modelling of an animal occupied zone using an anisotropic porous medium model with velocity depended resistance parameters

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    The airflow in dairy barns is affected by many factors, such as the barn's geometry, weather conditions, configurations of the openings, cows acting as heat sources, flow obstacles, etc. Computational fluids dynamics (CFD) has the advantages of providing detailed airflow information and allowing fully-controlled boundary conditions, and therefore is widely used in livestock building research. However, due to the limited computing power, numerous animals are difficult to be designed in detail. Consequently, there is the need to develop and use smart numerical models in order to reduce the computing power needed while at the same time keeping a comparable level of accuracy. In this work the porous medium modeling is considered to solve this problem using Ansys Fluent. A comparison between an animal occupied zone (AOZ) filled with randomly arranged 22 simplified cows' geometry model (CM) and the porous medium model (PMM) of it, was made. Anisotropic behavior of the PMM was implemented in the porous modeling to account for turbulence influences. The velocity at the inlet of the domain has been varied from 0.1 m s(-1) to 3 in s(-1) and the temperature difference between the animals and the incoming air was set at 20 K. Leading to Richardson numbers Ri corresponding to the three types of heat transfer convection, i.e. natural, mixed and forced convection. It has been found that the difference between two models (the cow geometry model and the PMM) was around 2% for the pressure drop and less than 6% for the convective heat transfer. Further the usefulness of parametrized PMM with a velocity adaptive pressure drop and heat transfer coefficient is shown by velocity field validation of an on-farm measurement

    Effect of Fans’ Placement on the Indoor Thermal Environment of Typical Tunnel-Ventilated Multi-Floor Pig Buildings Using Numerical Simulation

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    An increasing number of large pig farms are being built in multi-floor pig buildings (MFPBs) in China. Currently, the ventilation system of MFPB varies greatly and lacks common standards. This work aims to compare the ventilation performance of three popular MFPB types with different placement of fans using the Computational Fluid Dynamics (CFD) technique. After being validated with field-measured data, the CFD models were extended to simulate the air velocity, air temperature, humidity, and effective temperature of the three MFPBs. The simulation results showed that the ventilation rate of the building with outflowing openings in the endwall and fans installed on the top of the shaft was approximately 25% less than the two buildings with fans installed on each floor. The ventilation rate of each floor increased from the first to the top floor for both buildings with a shaft, while no significant difference was observed in the building without a shaft. Increasing the shaft’s width could mitigate the variation in the ventilation rate of each floor. The effective temperature distribution at the animal level was consistent with the air velocity distribution. Therefore, in terms of the indoor environmental condition, the fans were recommended to be installed separately on each floor

    Effects of Vitamin D Supplementation on Renal Function, Inflammation and Glycemic Control in Patients with Diabetic Nephropathy: a Systematic Review and Meta-Analysis

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    Background/Aims: Vitamin D (VD) is widely recognized as renal protective. However, whether VD supplementation provides benefit to patients with diabetic nephropathy (DN) remains controversial. Here, we performed a meta-analysis to systematically evaluate the impact of VD supplementation on indexes of renal function, inflammation and glycemic control in DN patients, and to explore the potential renal protective mechanism of VD. Methods: We searched Pubmed, Embase, Cochrane Library, and three major Chinese biomedical databases (CNKI, WANGFANG and VIP) for randomized controlled trials (RCTs) examining the effects of VD or its analogs in DN patients, published between September 2007 and July 2018. Quality assessment and data extraction were performed independently by two authors, according to the Cochrane systematic review methods. Meta-analysis based on the extracted results were performed via Revman 5.2 software. Results: We included 20 RCTs representing 1,464 patients with DN in this meta-analysis. VD supplementation significantly reduced 24-hour urine protein [MD = -0.26; 95% CI (-0.34, -0.17); P < 0.00001; I2 = 95%], UAER [MD = -67.36; 95% CI (-91.96, -42.76); P < 0.00001; I2 = 97%], hs-CRP [MD = -0.69; 95% CI (-0.86,-0.53); P < 0.00001; I2 = 0%], TNF-α [MD = -56.79; 95% CI (-77.05, -36.52); P < 0.00001; I2 = 89%] and IL-6 [MD = -0.73; 95% CI(-1.03, -0.44); P < 0.00001; I2 = 0%]. However, VD supplementation failed to decrease SCr [MD = -0.83; 95% CI (-3.67,2.02); P = 0.57; I2 = 0%] or increase eGFR [MD = 2.13; 95% CI (-2.06, 6.32); P = 0.32; I2 = 0%]. In addition, VD supplementation showed no impact on indexes of glycemic control, such as HbA1c [MD = 0.01; 95% CI (-0.09, 0.11); P = 0.84; I2 = 0%] and FBG [MD = -0.05; 95% CI (-0.29, 0.20); P = 0.70; I2 = 0%]. Analysis of 24-hour urine protein, SCr, eGFR, hs-CRP or HbA1c revealed no difference between subgroups based on the type of VD supplementation, including calcitriol, alfacalcidol and vitamin D3, and the dose or duration of calcitriol usage. Conclusion: In patients with DN, VD supplementation provides beneficial effects on 24-hour urine protein and inflammation indexes, but not on SCr, eGFR or glycemic control indexes. More RCTs that comprehensively evaluate the impact of VD supplementation on indexes of renal function, inflammation and glycemic control in DN atients are required in order to reach conclusive results

    Primary prevention for risk factors of ischemic stroke with Baduanjin exercise intervention in the community elder population: study protocol for a randomized controlled trial

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    BACKGROUND: Stroke is a major cause of death and disability in the world, and the prevalence of stroke tends to increase with age. Despite advances in acute care and secondary preventive strategies, primary prevention should play the most significant role in the reduction of the burden of stroke. As an important component of traditional Chinese Qigong, Baduanjin exercise is a simple, safe exercise, especially suitable for older adults. However, current evidence is insufficient to inform the use of Baduanjin exercise in the prevention of stroke. The aim of this trail is to systematically evaluate the prevention effect of Baduanjin exercise on ischemic stroke in the community elder population with high risk factors. METHODS: A total of 170 eligible participants from the community elder population will be randomly allocated into the Baduanjin exercise group and usual physical activity control group in a 1:1 ratio. Besides usual physical activity, participants in the Baduanjin exercise group will accept a 12-week Baduanjin exercise training with a frequency of five days a week and 40 minutes a day. Primary and secondary outcomes will be measured at baseline, 13 weeks (at end of intervention) and 25 weeks (after additional 12-week follow-up period). DISCUSSION: This study will be the randomized trial to evaluate the effectiveness of Baduanjin exercise for primary prevention of stroke in community elder population with high risk factors of stroke. The results of this trial will help to establish the optimal approach for primary prevention of stroke. TRIAL REGISTRATION: Chinese Clinical Trial Registry: ChiCTR-TRC-13003588. Registration date: 24 July, 2013
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