Additional file 1: of Stereotactic body-radiotherapy boost dose of 18 Gy vs 21 Gy in combination with androgen-deprivation therapy and whole-pelvic radiotherapy for intermediate- or high-risk prostate cancer: a study protocol for a randomized controlled, pilot trial

Table S1. SPIRIT 2013 Checklist. (DOCX 62 kb

DataSheet1_Lithium doped biphasic calcium phosphate: Structural analysis and osteo/odontogenic potential in vitro.PDF

Biphasic calcium phosphate (BCP) is generally considered a good synthetic bone graft material with osteoinductive potential. Lithium ions are trace elements that play a role in the bone-remodeling process. This study aimed to investigate the effects of lithium ions on the phase, crystal structure, and biological responses of lithium doped BCPs and to identify improvements in their osteogenic properties. Lithium-doped BCP powders with different doping levels (0, 5, 10, and 20 at%) were synthesized via the co-precipitation method. We found that the four types of lithium-doped BCP powders showed different phase compositions of hydroxyapatite and β-tricalcium phosphate. In addition, lithium ions favored entering the β-tricalcium phosphate structure at the Ca (4) sites and calcium vacancy sites [VCa(4)] up to 10 at%. This substitution improves the crystal stabilization by filling the vacancies with Ca2+ and Li+ in all Ca sites. However, when the concentration of Li ions was higher than 10 at%, lithium-induced crystal instability resulted in the burst release of lithium ions, and the osteogenic behavior of human dental pulp stem cells did not improve further. Although lithium ions regulate osteogenic properties, it is important to determine the optimal amount of lithium in BCPs. In this study, the most effective lithium doping level in BCP was approximately 10 at% to improve its biological properties and facilitate medical applications.</p

Additional file 1: of The regional association between bronchiectasis and lung cancer in chest CT

Figure S1. Example CT images of (A) underlying bronchiectasis and newly diagnosed lung cancer existing in the same lobe and (B) secondary traction bronchiectasis caused by lung cancer. (ZIP 7247 kb

Physical properties of ultrafine-grained polycrystals of magnesium based alloys

The objective of the thesis is the study of microstructure evolution, mechanical properties, defect structure and corrosion resistance of ultra-ne grained magnesium alloy AZ31 prepared by a combined two-step process: the extrusion and the equal-channel angular pressing (ECAP). The microstructure development was studied using light and transmission electron microscopy and electron backscatter diffraction (EBSD). Mechanical properties were studied by microhardness measurement and tensile tests and the defect structure by positron annihilation spectroscopy (PAS). The results of tensile tests indicates that the characteristic stress 0.2 increases slightly with increasing number of ECAP passes only to the second pass and then decreases signicantly with additional ECAP straining. This behaviour is in accordance with the results of PAS. EBSD measurements show that the microstructure of extruded and ECAPed material has a bimodal distribution of grain sizes. The bimodal distribution becomes homogeneous with increasing number of ECAP passes and no remaining large grains are observed after 8 passes. The average grain size in the specimen after 8 passes is in the submicrometer range and the fraction of high-angle grain boundary (HAGB) is approximately 80%. The extruded specimens after 8 ECAP passes show the best..

MOESM1 of Complete genome sequence of Clostridium perfringens CBA7123 isolated from a faecal sample from Korea

Additional file 1: Figure S1. A photomicrograph of Clostridium perfringens strain CBA7123 using Variable Pressure Field Emission Scanning Electron Microscope (VP-FE-SEM). Figure S2. Comparison of genomic structure between Clostridium perfringens CBA7123 and strains FORC 003, FORC 025, JP55, and JP838, using a progressive alignment algorithm in Mauve. The locally collinear blocks with identical colors represent highly homologous regions. The genomes were figured based on scale of the genome of strain CBA7123

Additional file 8: of Transcriptome and metabolome analysis in shoot and root of Valeriana fauriei

Primers used to amplify V. fauriei genes. (XLS 40 kb

Additional file 7: of Transcriptome and metabolome analysis in shoot and root of Valeriana fauriei

Amount of other volatile compounds in V. fauriei by solid-phase micro-extraction (%). (XLS 34 kb

Additional file 2: of Transcriptome and metabolome analysis in shoot and root of Valeriana fauriei

Carotenoid biosynthesis pathway in plants. CCD, carotenoid cleavage dioxygenases; CHXB, β-ring hydroxylase; CHXE, ε-ring hydroxylase, CrtISO; carotenoid isomerase; LCYB, lycopene β-cyclase; LCYE, lycopene ε-cyclase; NCED, nine-cis-epoxycarotenoiddioxygenanses; PDS, phytoene desaturase; PSY, phytoene synthase; ZDS, ζ-carotene desaturase; ZEP, zeaxanthin epoxidase. (PDF 154 kb

Additional file 1: Table S1. of Characterization of background noise in capture-based targeted sequencing data

Findings and methods from studies charactering artifactual substitutions in sequencing data. (DOCX 29 kb