キノコの成分研究(第29報)チョレイのステロール成分について

Five steroles were isolated from the sclerotium of Polyporus umbellatus FRIES (Polyporaceae) and identified as (22E)-ergosta-5,7,9(11),22-tetraen-3β-ol (1),ergosta-5,7-dien-dien-3β-ol (2), ergost-7-en-3β-ol (3),(22E)-ergosta-6,8(14),22-trien-3β-ol (4),and (22E)-ergosta-8(14),22-dien-3β-ol (5).Their structures were determined on the basis of spectral data.Compounds 1-5 have been isolated from the sclerotium of P.umbellatus for the first time

ムラサキハシドイの葉のセコイリドイド配糖体の構造並びにヒトがん細胞株に対する増殖阻害活性について

Two secoiridoid glycosides were isolates from the leaves of Syringa vulgaris L.(Oleaceae) and identifies as hydroxyframoside A (1) and neooleuropein (2).Their structures were determined on the basis of spectral data.Compound 1 has been isolated from the leaves of S.vulgaris for the first time. The growth inhibitory activity of compound 1 and 2 against 39 human cancer cell lines was evaluated

キノコの成分研究(第28報)エゾハリタケのステロール成分について

Eleven sterols were isolated from the fruiting bodies of Climacodon septentrionalis (Fr.) Karst. (Climacodontaceae) and identified as (22E)-ergosta-5,7,9(11),22-tetraen-3β-ol (1), ergosterol (2), ergosta-5,7-dien-3β-ol (3), (22E)-ergosta-5,8,22-trien-3β-ol (4), (22E)-ergosta-7,22-dien-3β-ol (5), ergost-7-en-3β-ol (6), ergosterol peroxide (7), 5α,8α-epidioxy-(22E)-ergosta-6,9(11),22-trien-3β-ol (8), 5α,6α-epoxy-(22E)-ergosta-8(14),22-diene-3β,7α-diol (9), 6β-methoxy-(22E)-ergosta-7,22-diene-3β,5α-diol (10), and 6β-methoxy-(22E)-ergosta-7,22-diene-3β,5α,9α-triol (11). Their structures were determined on the basis of spectral data. Compounds 1-11 have been isolated from the fruiting bodies of C. septentrionalis for the first time

ハクトウオウの化学成分(第1報) Hederagonic Acidの同定並びに立体配座について

From the roots of Pulsatilla chinensis (BUNGE) REGEL (Ranunculaceae),hederagonic acid (1) was isolated and identified on the basis of spectral data.Compound 1 has been isolated from the roots of this plant for the first time.Some correlations in the HMBC and NOESY spectra of compound 1 suggested the existence of a conformational equilibrium on the C23-hydroxyl group

キノコの成分研究(第25報)ヤマブシタケ子実体の新規芳香族化合物の化学構造について

Three new aromatic compounds, 6-[(2\u27E)-3\u27, 7\u27-dimethyl-5\u27-oxo-2\u27, 6\u27-octadienyl]-7-hydroxy-5-methoxy-1(3H)-isobenzofuranone (1), 5-[(2\u27E)-3\u27, 7\u27-dimethyl-5\u27-hydroxy-2\u27-octenyl]-4-hydroxy-6-methoxy-1(3H)-isobenzofuranone (2) and 3, 4-dihydro-5-methoxy-2-methyl-2-(4\u27-methyl-2\u27-oxo-3\u27-pentenyl)-9(7H)-oxo-2H-furo[3, 4-h]benzopyran (3), were isolated from the fruiting bodies of Hericium erinaceum (BULL.: FR.) PERS. (Hericiaceae). The structures of the new compounds were elucidated on the basis of spectral data

キノコの成分研究(第23報)シロハツより単離されたセスキテルペノイド,Lactarorufin Bの立体配座解析及び絶対構造

The conformation of lactarorufin B (1), a sesquiterpenoid isolated from the fruiting bodies of Russula delica, have been investigated by NMR method. Analyses of the ^1H-NMR spectra in CD_3OD at low temperatures indicate that 1 exists as a mixture of two stable conformations on the seven-membered ring in a 87 : 13 ratio which are found to be chair form and twist-boat form, respectively. The absolute stereochemistry of 1 was determined by circular dichroism (CD) spectrum

メタカラコウ属植物の成分研究(第9報) : マルバダケブキの根の新規ノルセスキテルペノイドの化学構造について

Three new norsesquiterpenoids, liguladentanorol (1), 8α-hydroxyligudentatol (2) and 8α-hydroxyligujapone (3), have been isolated from the roots of Ligularia dentata HARA (Compositae). The structures of these new compounds were determined on the basis of their spectral data

キノコの成分研究(第27報)イロガワリのステロール成分について

Six sterols were isolated from the fruiting bodies of Boletus pulverulentus OPAT. (Boletaceae) and identified as (22E)-ergosta-5,7,9(11),22-tetraen-3β-ol (1), ergosterol (2), ergosta-5,7-dien-3β-ol (3), (22E)-ergosta-5,8,22-trien-3β-ol (4), (22E)-ergosta-7,22-dien-3β-ol (5) and ergost-7-en-3β-ol (6). The structures were elucidated on the basis of their spectral data. Compounds 1-6 have been isolated from the fruiting bodies of B. pulverulentus for the first time

キクイモHelianthus tuberosus L.の葉のセスキテルペノイド成分について

Six sesquiterpenoids, 1α-acetoxypinnatifidin (1), 1α-hydroxypinnatifidin (2), budlein A (3), 17, 18-dehydroviguiepinin (4), 4, 15-isoatriplicolide angelate (5) and 4, 15-isoatriplicolide methylacrylate (6), have been isolated from the leaves of Helianthus tuberosus L. (Compositae). Their structures were determined on the basis of spectral data. Compound 1 is a new natural product but primarily synthetic substance and compound 2 was obtained from the leaves of H. tuberosus for the first time