Evolution of the texture of low-carbon microalloyed pipe steel in the seamless pipe manufacturing process

A method of orientation microscopy (with the application of the EBSD technique) is used in investigation of the microstructure and texture in steel 0.08 % C-Cr-Mo-V formed at different stages of the seamless pipe manufacturing process, namely, after hot finishing and after full quenching with subsequent high-temperature tempering. It is shown that, at the final stage of hot finishing followed by heat treatment, the texture is represented by four scattered orientations. The found texture inheritance in the investigated material is presumably related to reproduction of special circa Σ3 boundaries between crystal grains at each phase transition. © 2016 Author(s)

Study of the structure and kinematics of the NGC 7465/64/63 triplet galaxies

This paper is devoted to the analysis of new observational data for the group of galaxies NGC 7465/64/63, which were obtained at the 6-m telescope of the Special Astrophysical Observatory of the Russian Academy of Sciences (SAO RAS) with the multimode instrument SCORPIO and the Multi Pupil Fiber Spectrograph. For one of group members (NGC 7465) the presence of a polar ring was suspected. Large-scale brightness distributions, velocity and velocity dispersion fields of the ionized gas for all three galaxies as well as line-of-sight velocity curves on the basis of emission and absorption lines and a stellar velocity field in the central region for NGC 7465 were constructed. As a result of the analysis of the obtained information, we revealed an inner stellar disk (r ~ 0.5 kpc) and a warped gaseous disk in addition to the main stellar disk, in NGC 7465. On the basis of the joint study of photometric and spectral data it was ascertained that NGC 7464 is the irregular galaxy of the IrrI type, whose structural and kinematic peculiarities resulted most likely from the gravitational interaction with NGC 7465. The velocity field of the ionized gas of NGC 7463 turned out typical for spiral galaxies with a bar, and the bending of outer parts of its disk could arise owing to the close encounter with one of galaxies of the environment.Comment: 20 pages, 6 figure

Modern microwave methods in solid state inorganic materials chemistry: from fundamentals to manufacturing

No abstract available

Prospects for the use of mobile learning in the preparation of specialists in the field of commerce

Рассматриваются социально-экономические условия становления специалиста сферы коммерции в вузе и формирования его профессиональной культуры на основе компетентностного подхода с использованием современных информационных технологий. Приведены возможности внедрения мобильных технологий обучения в образовательный процесс при подготовке специалистов сферы коммерции в высшей школе. Анализируются достоинства мобильного обучения, даются практические советы для организации изучения курса товароведения с применением современных средств свзязи, таких как смартфоны и планшетные компьютеры. Описываются недостатки и сложности внедрения мобильной технологии, а также возможные пути решения возникающих проблем.We consider the socio-economic conditions of development of the specialist areas of commerce in high school and the formation of its professional culture based on competence-based approach with the use of modern information technology. Given the possibility of the introduction of mobile learning technologies in the educational process in the preparation of specialists in the sphere of commerce in high school. Analyzes the advantages of mobile learning, practical advice for the organization of the study course of merchandising with the use of modern svzyazi such as smartphones and tablet computers. Describes the pitfalls and difficulties of implementation of mobile techno-logy, as well as possible solutions to problems

Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane.

Hepatitis B virus (HBV) infection is a major health threat causing 880,000 deaths each year. Available therapies control viral replication, but do not cure HBV leaving patients at risk to develop hepatocellular carcinoma. Here we show that HBV envelope proteins (HBs) - besides their integration into endosomal membranes - become embedded in the plasma membrane where they can be targeted by redirected T-cells. HBs was detected on the surface of HBV-infected cells, in livers of mice replicating HBV and in HBV-induced hepatocellular carcinoma. Staining with HBs-specific recombinant antibody MoMab recognizing a conformational epitope indicated that membrane-associated HBs remains correctly folded in HBV-replicating cells in cell culture and in livers of HBV-transgenic mice in vivo. MoMab coated onto superparamagnetic iron oxide nanoparticles allowed to detect membrane-associated HBs after HBV infection by electron microscopy in distinct stretches of the hepatocyte plasma membrane. Last not least we demonstrate that HBs located to the cell surface allows therapeutic targeting of HBV-positive cells by T-cells either engrafted with a chimeric antigen receptor or redirected by bispecific, T-cell engager antibodies. This article is protected by copyright. All rights reserved