443 research outputs found
An sTGC Prototype Readout System for ATLAS New-Small-Wheel Upgrade
This paper presents a readout system designed for testing the prototype of
Small-Strip Thin Gap Chamber (sTGC), which is one of the main detector
technologies used for ATLAS New-Small-Wheel Upgrade. This readout system aims
at testing one full-size sTGC quadruplet with cosmic muon triggers
Additive Manufacturing Of SiC-Sialon Refractory With Excellent Properties By Direct Ink Writing
Additive manufacturing of SiC-Sialon refractory with complex geometries was achieved using direct ink writing processes, followed by pressure less sintering under nitrogen. The effects of particle size of SiC powders, solid content of slurries and additives on the rheology, thixotropy and viscoelasticity of ceramic slurries were investigated. The optimal slurry with a high solid content was composed of 81 wt% SiC (3.5 µm+0.65 µm), Al2O3 and SiO2 powders, 0.2 wt% dispersant, and 2.8 wt% binder. Furthermore, the accuracy of the structure of specimens was improved via adjustment of the printing parameters, including nozzle size, extrusion pressure, and layer height. The density and flexural strength of the printed SiC-Sialon refractory sintered at 1600 °C were 2.43 g/cm3 and 85 MPa, respectively. In addition, the printed SiC-Sialon crucible demonstrated excellent corrosion resistance to iron slag. Compared to the printed crucible bottom, the crucible side wall was minimally affected by molten slag
Socio-Economic Factors of Empowerment in Developing Countries
The study is carried to identify the main socio economic cultural and political view determinants of women empowerment in the developing countries. The highest determination of the study is to analyze and identify the variables through which the process of women empowerment can be measured. This study is based on secondary data and reported to analyze the empowerment factor of women in 124 developing countries, the data was ordinal in nature and randomly selected from the population. The main investigation of this research study to analyzed the relationship of women fertility, socio-economic and political factor on the women empowerment. After conducting a cross sectional study for the most recent period, the findings of study show that the main deterrents towards women disempowerment are attributed as high fertility rates, high maternal mortality, gender inequality, lack of female’s access towards education, health and economic opportunities, lack of leadership and decision making qualities. It is found that a patriarchal culture is equally responsible for women in sufferings and disempowerment. However, democracy and democratic culture can contribute well in upgrading the process of women empowerment in developing countries
Research on Trust Propagation Models in Reputation Management Systems
Feedback based reputation systems continue to gain popularity in eCommerce and social media systems today and reputation management in large social networks needs to manage cold start and sparseness in terms of feedback. Trust propagation has been widely recognized as an effective mechanism to handle these problems. In this paper we study the characterization of trust propagation models in the context of attack resilience. We characterize trust propagation models along three dimensions: (i) uniform propagation and conditional propagation, (ii) jump strategies for breaking unwanted cliques, and (iii) decay factors for differentiating recent trust history from remote past history. We formally and experimentally show that feedback similarity is a critical measure for countering colluding attacks in reputation systems. Without feedback similarity guided control, trust propagations are vulnerable to different types of colluding attacks
Resveratrol protects against sepsis induced acute kidney injury in mice by inducing Klotho mediated apoptosis inhibition
Purpose: To investigate the mechanism of resveratrol protection against sepsis-induced acute kidney injury in mice.
Methods: A sepsis-induced acute kidney injury model was established in mice by cecal ligation and puncture (CLP). Sixty healthy male ICR mice were randomly divided into the sham operation (sham) group, sepsis-induced acute kidney injury model (CLP) group, CLP + low-dose (20 mg/kg) resveratrol treatment (CLP + ResL) group, CLP + high-dose (40 mg/kg) resveratrol treatment (CLP + ResH) group and CLP + Klotho (0.01 mg/kg) treatment (CLP + Klotho) group. All mice were administered treatment on the day after surgery and once every 24 h for 3 days. Various serum biochemical parameters and protein expressions were evaluated.
Results: After CLP, the levels of serum creatinine (Scr) and blood urea nitrogen (BUN) increased and the pathology was exacerbated. The protein and mRNA expression levels of Klotho and Bcl-2 decreased, while those of Bax and Caspase-3 increased (p < 0.05). After resveratrol and Klotho protein intervention, Scr and BUN levels recovered, and pathological changes were alleviated. The protein and mRNA expression levels of Klotho and Bcl-2 increased, while those of Bax and Caspase-3 decreased. The conditions of the mice in CLP + ResH group and the CLP + Klotho group improved more significantly than those of the mice in the CLP + ResL group (p < 0.05).
Conclusion: Resveratrol upregulates the expression of endogenous Klotho to exert its antiapoptotic effects, which can protect the kidneys of mice against sepsis-induced acute kidney injury. Thus, the compound has potentials for development for protection against acute kidney injury
FM-DBEM Simulation of 3D Microvoid and Microcrack Graphite Models
The graphite is porous medium, and the geometry and size distribution of its structural deficiencies such as microcracks and microvoids at different oxidation degrees have a great influence on the overall performance. In this paper, we adopt the FM-DBEM to study 3D models which contain spheroidal microvoids and circular microcracks. The accuracy of this method is tested by a comparison to the theoretical solution to the problem of 2D microcrack and microvoid interaction problem. Two simulations are conducted: the simulation of graphite model containing a large number of randomly distributed microcracks and microvoids and the simulation of graphite model containing microcracks and growing microvoids. The simulations investigate the effective moduli versus the two microstructures’ density and the effect of microvoid’s growth on the SIF of microcrack
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