1,404 research outputs found

    阿爾泰哈巴河群的沉積時代及其構造背景

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    Habahe Group mainly consists of elastic sediments, which widely distribute in the Chinese Altai and can provide important constraints on the tectonic evolution of the Central Asian Orogenic Belt (CAOB). However, there are different opinions about its deposition time and tectonic background. Previous studies suggested that the Habahe Group formed in Sinian to Mid-Ordovician or Mid- to Late Ordovician in a passive continental margin. On the other hand, recent geological investigations reveal a long lasting subduction-related setting in the Chinese Altai at least since Cambrian. The current geochronological study for detrital zircons from the Habahe Group reveals that the detrital zircons of individual samples, irrespective of their lithological and metamorphic differences, all show similar age patterns, with the early Paleozoic ( 206Pb/ 238U age = 463 ± 542Ma) grains predominating. The youngest detrital zircons from different samples display similar ages (ca. 470Ma), which may reflect the maximum deposition time of the Habahe Group. Dating of growth rim of detrital zircons from migmatite yielded a Mid-Devonian age (384 ± 6Ma), which was coeval with intrusion of Early to Mid-Devonian granitic plutons in the area and clearly indicates the minimum deposition time of the Hababe Group. Therefore, the deposition time of the Habahe Group can be constrained to be Mid-Ordovician to Early Devonian. Zircon U Pb dating results indicate that the detrital zircons of the Habahe Group are dominated by early Paleozoic grains, with small proportion formed in Precambrian. The early Paleozoic detrital zircons are mostly magmatic in origin, and their less rounded shapes indicate a limited transportation. The age and morphological characteristics of the detrital zircons are consistent with those of detrital zircons in active tectonic settings and indicate that the Chinese Altai was under an active continental margin environment during the Early Paleozoic. 北疆阿爾泰造山帶的哈巴河群變質碎屑巖分布廣泛,其沉積時代和構造環境對于認識中亞造山帶的演化歷史有重要意義。早期研究認為哈巴河群沉積于震旦紀—中奧陶世時期,形成于被動大陸邊緣構造環境。而最近有學者根據中亞造山帶的地質演化背景提出,阿爾泰形成于活動陸緣構造環境。對哈巴河群中碎屑鋯石的年代學研究表明,不同巖性或變質程度不同的樣品碎屑鋯石主要類群具有相似的年齡分布特征,其206Pb/238U 年齡主要介于463~542Ma 之間。在這些樣品中, 最年輕的碎屑鋯石年齡均集中于470Ma 左右,代表了碎屑沉積的時代下限。而哈巴河群混合巖樣品中碎屑鋯石增生邊形成于中泥盆世晚期(384±6Ma),與侵入該群的早古生代花崗巖的年齡十分接近,大致反映了哈巴河群碎屑巖沉積時代的上限,因此哈巴河群的沉積時代應在早泥盆世—中奧陶世之間。鋯石的形態和內部結構特征顯示哈巴河群的年輕碎屑鋯石類群(463~542Ma)主要為巖漿鋯石,其磨圓度較差,而且在比例上遠高于前寒武紀碎屑鋯石。上述特點與活動大陸邊緣碎屑鋯石類群分布特征完全一致,反映阿爾泰在中奧陶世至早泥盆世可能處于活動大陸邊緣構造環境。postprin

    A dynamic and continuous allowances allocation methodology for the prevention of carbon leakage: Emission control coefficients

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    © 2018 Elsevier Ltd Carbon leakage has become the core issue of emission trading systems. Using data from Hubei Province, this paper identifies the drawbacks of the prevailing methods for preventing carbon leakage and proposes a new methodology to overcome them, namely, Emission Control Coefficients. In contrast to the common tiered structure method, the Emission Control Coefficients generate a dynamic and continuous emission control coefficient for each industry which will improve the effectiveness and fairness of allowance allocation, set aside sufficient time for the low carbon transformation of industries, and balance the needs to protect competitiveness and decarbonize and are particularly suitable for the emission trading systems of developing counties. This paper makes three main academic contributions: Firstly, it proposes a new indicator, the abatement potential for more effective determining allowance allocation than the prevailing method. Secondly, it better distinguishes industrial differences. Thirdly, it can better respond to the problem of excess allowances that is due to technological advances and trade pattern changes

    Lead-free multilayer piezoelectric transformer

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    Author name used in this publication: K. H. LamAuthor name used in this publication: S. WangAuthor name used in this publication: C. L. SunAuthor name used in this publication: X. Z. Zhao2006-2007 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

    Deformation of the Fermi surface in the extended Hubbard model

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    The deformation of the Fermi surface induced by Coulomb interactions is investigated in the t-t'-Hubbard model. The interplay of the local U and extended V interactions is analyzed. It is found that exchange interactions V enhance small anisotropies producing deformations of the Fermi surface which break the point group symmetry of the square lattice at the Van Hove filling. This Pomeranchuck instability competes with ferromagnetism and is suppressed at a critical value of U(V). The interaction V renormalizes the t' parameter to smaller values what favours nesting. It also induces changes on the topology of the Fermi surface which can go from hole to electron-like what may explain recent ARPES experiments.Comment: 5 pages, 4 ps figure

    Design, synthesis and biological characterization of novel inhibitors of CD38

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    Human CD38 is a novel multi-functional protein that acts not only as an antigen for B-lymphocyte activation, but also as an enzyme catalyzing the synthesis of a Ca 2+ messenger molecule, cyclic ADP-ribose, from NAD +. It is well established that this novel Ca 2+ signaling enzyme is responsible for regulating a wide range of physiological functions. Based on the crystal structure of the CD38/NAD + complex, we synthesized a series of simplified N-substituted nicotinamide derivatives (Compound1-14). A number of these compounds exhibited moderate inhibition of the NAD + utilizing activity of CD38, with Compound4 showing the highest potency. The crystal structure of CD38/Compound4 complex and computer simulation of Compound7 docking to CD38 show a significant role of the nicotinamide moiety and the distal aromatic group of the compounds for substrate recognition by the active site of CD38. Biologically, we showed that both Compounds4 and 7 effectively relaxed the agonist-induced contraction of muscle preparations from rats and guinea pigs. This study is a rational design of inhibitors for CD38 that exhibit important physiological effects, and can serve as a model for future drug development. © 2011 The Royal Society of Chemistry.postprin

    Solvothermal Synthesis of Ternary Sulfides of Sb2 − xBixS3(x = 0.4, 1) with 3D Flower-Like Architectures

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    Flower-like nanostructures of Sb2 − xBixS3(x = 0.4, 1.0) were successfully prepared using both antimony diethyldithiocarbamate [Sb(DDTC)3] and bismuth diethyldithiocarbamate [Bi(DDTC)3] as precursors under solvothermal conditions at 180 °C. The prepared Sb2 − xBixS3 with flower-like 3D architectures were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray spectrometry (EDS), high-resolution transmission electron microscopy (HRTEM), and selected area electron diffraction (SAED). The flower-like architectures, with an average diameter of ~4 μm, were composed of single-crystalline nanorods with orthorhombic structures. The optical absorption properties of the Sb2 − xBixS3 nanostructures were investigated by UV–Visible spectroscopy, and the results indicate that the Sb2 − xBixS3 compounds are semiconducting with direct band gaps of 1.32 and 1.30 eV for x = 0.4 and 1.0, respectively. On the basis of the experimental results, a possible growth mechanism for the flower-like Sb2 − xBixS3 nanostructures is suggested

    Geochemical characteristics and 40Ar- 39Ar ages of the amphibolites and gabbros in Tarlang area: Implications for tectonic evolution of the Chinese Altai

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    Amphibolitic and gabbroic rocks occur in Tarlang area in Chinese Altay. Amphibolites are metamorphosed products of mafic magmatic rocks (SiO 2 = 45.42% - 52.96%) and contain high Al 2O 3 (13.14% - 17.92%), Fe 2O 3 T (9.08% - 16.88%) and TiO 2 (0.82% - 3.23%) contents. The amphibolite samples show relatively flat REE patterns, without significant fractionations of REEs (La/Yb N = 1.53 - 1.79). These samples are depleted in HFSEs slightly, with slightly Ti-Nb-Ta negative anomalies, which suggest a subtle relation to subduction-related environment. The gabbroic samples (SiO 2 = 46.96% - 49.86%) have intermediate TiO 2 (0.38% - 1.89%) and relatively low K 2 O contents (K 2 O = 0.34% - 1.03%), belonging to subalkali rocks (Na 2 O > K 2 O). They have relatively high Al 2O 3 (15.0% - 20.81%), CaO (10.13% - 11.60%) and moderate MgO (7.3% - 8.3% ) contents. The gabbroic samples show two types of REE patterns. One is characterized by slight fractionation of REEs (La/Yb N = 1.10 - 1.67) and weak Eu anomalies (δEu = 1.03 - 1.10), while the other is enriched in LREE s (La/Yb N = 5.97 - 6.39), with significantly positive Eu anomalies (δEu = 1.31 - 1.44), which may reflect accumulation of plagioclase in the magma chamber. These gabbroic rocks all exhibit Ti-Nb-Ta troughs and Pb-Sr spikes, also implying a subduction-related origin. The 40Ar/ 39Ar spectrum of the gabbroic sample is simple and flat (plateau age of 266.9 ± 4.2Ma; isochron age of 261 ± 23Ma), indicating that its K-Ar isotopic system was not seriously disturbed by subsequent thermal events and may reflect the intrusion time of the gabbro. However, 40Ar- 39Ar analysis of the amphibolite give rise to a saddle-like spectrum, and its youngest plateau (297.3 ± 6.1Ma) probably reflects the last metamorphic event. The difference on age and geochemistry between the amphibolitic and gabbroic rocks implies that they probably represent different mafic magma. The protolith of amphibolites probably formed in a seamount near a subduction zone and subsequently accreated to the Altai. The gabbro exhibits subduction-releted characteristics and was coeval with transtensional movement in the Chinese Altai, probably reflecting a tectonic transition in the Permian.阿爾泰塔爾浪地區出露一些斜長角閃巖和輝長巖。其中,斜長角閃巖為基性巖漿巖變質的產物,SiO_2含量為45.42%~52.96%,具有較高的Al_2O_3(13.14%~17.92%)、Fe_2O_3~T(9.08%~16.88%)和TiO_2(0.82%~3.23%)含量。斜長角閃巖樣品稀土元素曲線比較平坦,輕重稀土元素分餾不明顯(La/Yb_N=1.53~1.79),無明顯的Nb和Ta虧損。通過野外產狀及地球化學特征分析,認為該斜長角閃巖形成于海山的構造環境。輝長巖SiO_2(46.96%~49.86%)含量稍低,TiO_2(0.38%~1.89%)變化較大,并富Al_2O_3(15.0%~20.81%)、CaO(10.13%~11.60%),具有中等至較高MgO含量(7.3%~8.3%)和相對較低的鉀含量(K_2O=0.34%~1.03%),屬亞堿性巖石系列(Na_2O>K_2O)。輝長巖呈現兩種稀土元素組成特征。一種輕重稀土分餾不明顯,配分曲線比較平坦(La/Yb_N=1.10~1.67),具有輕微的Eu正異常(δEu=1.03~1.10);另一種輕重稀土元素分餾較明顯(La/Yb_N=5.97~...published_or_final_versio

    Continuous Regional Arterial Infusion with Fluorouracil and Octreotide Attenuates Severe Acute Pancreatitis in a Canine Model

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    Aim: To investigate the therapeutic effects of fluorouracil (5-Fu) and octreotide (Oct) continuous regional arterial infusion (CRAI,) alone or in combination, was administered in a canine model of severe acute pancreatitis (SAP). Materials and Methods: The animals were divided into five groups; group A (Sham), group B (SAP), group C (SAP and 5-Fu), group D (SAP and Oct), and group E (SAP and 5-Fu + Oct). Levels of amylase, alpha-tumor necrosis factor (TNF-alpha), blood urea nitrogen (BUN), creatinine, thromboxane B2 and 6-keto-prostaglandin F1 alpha were measured both before and after the induction of SAP. Pathologic examination of the pancreas and kidneys was performed after termination of the study. Results: Pathologic changes noted in the pancreas in SAP significantly improved following CRAI with either single or combined administration of 5-Fu and Oct, where combination therapy demonstrated the lowest injury score. All treatment groups had significantly lower levels of serum TNF-alpha and amylase activity (P<0.05), though only groups D and E had a lower BUN level as compared to group B. The plasma thromboxane B-2 level increased in SAP, but the ratio of thromboxane B-2/6-keto-prostaglandin F-1 alpha decreased in the treatment groups, with the combination therapy (group E) demonstrating the lowest ratio as compared to the other 3 experimental groups (P<0.05). Conclusions: The findings in the present study demonstrate an attenuation of SAP in a canine model following CRAI administration with 5-Fu or Oct, alone or in combination

    Gene and protein expression of glucose transporter 1 and glucose transporter 3 in human laryngeal cancer—the relationship with regulatory hypoxia-inducible factor-1α expression, tumor invasiveness, and patient prognosis

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    Increased glucose uptake mediated by glucose transporters and reliance on glycolysis are common features of malignant cells. Hypoxia-inducible factor-1α supports the adaptation of hypoxic cells by inducing genes related to glucose metabolism. The contribution of glucose transporter (GLUT) and hypoxia-inducible factor-1α (HIF-1α) activity to tumor behavior and their prognostic value in head and neck cancers remains unclear. The aim of this study was to examine the predictive value of GLUT1, GLUT3, and HIF-1α messenger RNA (mRNA)/protein expression as markers of tumor aggressiveness and prognosis in laryngeal cancer. The level of hypoxia/metabolic marker genes was determined in 106 squamous cell laryngeal cancer (SCC) and 73 noncancerous matched mucosa (NCM) controls using quantitative realtime PCR. The related protein levels were analyzed by Western blot. Positive expression of SLC2A1, SLC2A3, and HIF-1α genes was noted in 83.9, 82.1, and 71.7 % of SCC specimens and in 34.4, 59.4, and 62.5 % of laryngeal cancer samples. Higher levels of mRNA/protein for GLUT1 and HIF-1α were noted in SCC compared to NCM (p<0.05). SLC2A1 was found to have a positive relationship with grade, tumor front grading (TFG) score, and depth and mode of invasion (p<0.05). SLC2A3 was related to grade and invasion type (p<0.05). There were also relationships of HIF-1α with pTNM, TFG scale, invasion depth and mode, tumor recurrences, and overall survival (p<0.05). In addition, more advanced tumors were found to be more likely to demonstrate positive expression of these proteins. In conclusion, the hypoxia/metabolic markers studied could be used as molecular markers of tumor invasiveness in laryngeal cancer.This work was supported, in part, by the statutory fund of the Department of Cytobiochemistry, University of Łódź, Poland (506/811), and by grant fromtheNational Science Council, Poland (N403 043 32/2326)

    Greening China naturally

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    Author Posting. © The Author(s), 2011. This is the author's version of the work. It is posted here by permission of Springer for personal use, not for redistribution. The definitive version was published in AMBIO: A Journal of the Human Environment 40 (2011): 828-831, doi:10.1007/s13280-011-0150-8.China leads the world in afforestation, and is one of the few countries whose forested area is increasing. However, this massive ‘‘greening’’ effort has been less effective than expected; afforestation has sometimes produced unintended environmental, ecological, and socioeconomic consequences, and has failed to achieve the desired ecological benefits. Where afforestation has succeeded, the approach was tailored to local environmental conditions. Using the right plant species or species composition for the site and considering alternatives such as grassland restoration have been important success factors. To expand this success, government policy should shift from a forest-based approach to a results-based approach. In addition, long-term monitoring must be implemented to provide the data needed to develop a cost-effective, scientifically informed restoration policy.This work was supported by the Fundamental Research Funds for the Central Universities (HJ2010-3) and the CAS/ SAFEA International Partnership Program for Creative Research Teams of ‘‘Ecosystem Processes and Services’’
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