An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans

none24noneS. BONASSI; A. ZNAOR; M. CEPPI; C. LANDO; W.P. CHANG; N. HOLLAND; M. KIRSCH-VOLDERS; E. ZEIGER; S. BAN; R. BARALE; M.P. BIGATTI; C. BOLOGNESI; A. CEBULSKA-WASILEWSKA; E. FABIANOVA; A. FUCIC; L. HAGMAR; G. JOKSIC; A. MARTELLI; L. MIGLIORE; E. MIRKOVA; M.R. SCARFI; A. ZIJNO; H. NORPPA; M. FENECHS., Bonassi; A., Znaor; M., Ceppi; C., Lando; W. P., Chang; N., Holland; M., KIRSCH VOLDERS; E., Zeiger; S., Ban; R., Barale; M. P., Bigatti; C., Bolognesi; A., CEBULSKA WASILEWSKA; E., Fabianova; A., Fucic; L., Hagmar; G., Joksic; Martelli, ANTONIETTA MARIA; L., Migliore; E., Mirkova; M. R., Scarfi; A., Zijno; H., Norppa; M., Fenec

HUman MicroNucleus Project: International Database

stituto Nazionale per la Ricerca sul Molecular Toxicology Laboratory, Third Military Medical University, Chong Qing, China Laboratorio Dosimetria Biologica, Autoridad Regulatoria Nuclear, Buenos Aires, Argentina Auckland Cancer Society Research Centre, Auckland, New Zealand Institute for Medical Research end Occupational Health, Zagreb, Croatia Centro de Proteccion e Higiene de las Radiaciones, Havana, Cuba Department of Pharmacology, University of Bologna, Bologna, Italy Cell Biology Division, Bhabha Atomic Research Center, Mumbai, India Department of Radiation Oncology, Leo Jenkins Cancer Center, East Carolina University School of Medicine, Greenville, North Carolina Institute of Genetics and Cytology, Belarus Academy of Sciences, Minsk, Belarus Nacional Center of Hygiene, Medical Ecology and Nutrition, Sofia, Bulgaria Dipartimento di Agrobiologia e Agrochimica, Universita della Tuscia, Viterbo, Italy Institute fur Medizinische Strahlenbiologie,

Health Literacy in Taiwan: A Population-Based Study

Data on health literacy (HL) in the population is limited for Asian countries. This study aimed to test the validity of the Mandarin version of the European Health Literacy Survey Questionnaire (HLS-EU-Q) for use in the general public in Taiwan. Multistage stratification random sampling resulted in a sample of 2989 people aged 15 years and above. The HLS-EU-Q was validated by confirmatory factor analysis with excellent model data fit indices. The general HL of the Taiwanese population was 34.4 ± 6.6 on a scale of 50. Multivariate regression analysis showed that higher general HL is significantly associated with the higher ability to pay for medication, higher self-perceived social status, higher frequency of watching health-related TV, and community involvement but associated with younger age. HL is also associated with health status, health behaviors, and health care accessibility and use. The HLS-EU-Q was found to be a useful tool to assess HL and its associated factors in the general population

Work-related fatigue among medical personnel in Taiwan

Work-related fatigue among medical personnel is a major concern for patient safety, however heavy on-call duty is common in many hospitals. The purpose of this study was to investigate the prevalence of self-reported work-related fatigue and its associated factors. Methods: A cross-sectional survey of 1833 participants was conducted in two hospitals in Taipei City, Taiwan, using a self-administered questionnaire. Participants reported their demographic characteristics, health-related behavior, health status and symptoms, and work-related fatigue during the past 3 months. Results: The prevalence of work-related fatigue among the 1833 participants was 30.9%. Younger participants (20–29 years old) were more likely to report work-related fatigue than older participants (40–65 years old) [adjusted odds ratio (aOR) = 1.55, 95% confidence interval (CI) = 1.18–2.01]. Physicians, nurses, and medical technicians were more likely to report work-related fatigue symptoms than administrative personnel (aOR = 2.30, 95% CI = 1.57–2.79; aOR = 2.83, 95% CI = 1.87–3.99; and aOR = 2.01, 95% CI = 1.12–3.06, respectively). Those who drank coffee more than five times a week were more likely to report work-related fatigue than those who did not drink coffee at all (aOR = 2.53, 95% CI = 1.25–1.93). Participants with poor and very poor self-reported health were more likely to report work-related fatigue (aOR = 1.80, 95% CI = 1.26–2.38) than those who reported that their health was fair, good, or very good. Conclusion: We identified factors associated with work-related fatigue among hospital workers in Taipei City. These findings can be applied toward on-the-job training and the development of preventive measures for occupational safety in general hospitals

Health-related behaviors moderate the association between age and self-reported health literacy among Taiwanese women

The role of health-related behaviors in the association between age and health literacy has not been well-elucidated. The present cross-sectional study evaluated the interactions between age and health-related behaviors in 942 women in Taiwan between February and October 2013. Women aged 18-78 years were randomly sampled and recruited from the national administrative system. Self-reported health literacy was measured by the European Health Literacy Survey Questionnaire (HLS-EU-Q47) in Mandarin, asking about sociodemographics and essential health-related behaviors (watching health-related television, community involvement). The interviews were conducted confidentially by well-trained interviewers after having participants' consent. In multiple linear regression models adjusted for education attainment, self-perceived social status, ability to pay for medication, and health-related behaviors, health literacy was significantly negatively related to age (unstandardized regression coefficient, B = -0.04; 95% confidence interval [CI] = (-0.07; 0.00); p = .03). The lower health literacy among older women was significantly modified by watching health-related television programs (from "rarely/not-at-all", B = -0.08 (-0.12, -0.04), p < .001 to "often"; B = 0.10 (0.07, 0.12); p < .001) and community involvement (from "rarely/not-at-all", B = -0.06 (-0.10, -0.03); p = .001 to "often", B = 0.06 (0.03, 0.08); p < .001). Specific health behaviors were protective of older women's health literacy and likely their health