QUALITATIVE REVIEW OF ANTIBIOTIC USE FOR NEONATAL SEPSIS

Objective: The aim of this study is to evaluate the antibiotic use in neonates with sepsis.Methods: An observational retrospective study was conducted using medical records of neonates diagnosed with early-/late-onset sepsis who wereprescribed antibiotics and who were treated in the neonatal intensive care unit (NICU) at the Dr. Cipto Mangunkusumo Hospital between January 1 andDecember 31, 2015. Patient records were screened for antibiotic use; qualitative analyses were performed using the Gyssens algorithm. Concordanceof empirical antibiotic prescriptions with subsequent blood culture and sensitivity tests was evaluated.Results: A total of 176 sepsis cases included 80 and 96 neonates with normal and low birth weights (LBWs), respectively. Ampicillinsulbactam+gentamycin, which is indicated in local guidelines as the first-line antibiotic combination for neonatal sepsis, was most frequentlyprescribed. In the normal birth weight group, appropriate antibiotic use (Gyssens Category I) was found in 89.7% of cases, whereas Gyssens Category V(no indication) was found in 4.54% of cases. In the LBW group, 88.1% and 6.2% of cases were included in Gyssens Categories I and V, respectively.Only 17.5% and 13.5% cultured blood specimens from normal and LBW groups, respectively, yielded positive results; the most commonly identifiedbacteria were Acinetobacter baumannii and Klebsiella pneumonia. All isolates were resistant to ampicillin-sulbactam; only 7.4% were sensitive togentamicin.Conclusion: Antibiotic use for neonatal sepsis in NICU in this study can be considered appropriate, suggesting proper implementation of antimicrobialguidelines. However, high rates of resistance to the first-line antibiotics for neonatal sepsis are concerning

Penyuluhan Vitamin dan Supplemen yang Dibutuhkan Tubuh Lansia di Kelurahan Tidung, Pulau Seribu 17-19 Juni 2022

Pandemic COVID-19 (coronavirus) menyebabkan banyak perubahan dalam kehidupan sehari-hari. Gizi yang baik, sangat penting sebelum, selama dan setelah infeksi. Kecukupan gizi terutama vitamin dan mineral sangat diperlukan dalam mempertahankan sistem kekebalan tubuh yang optimal, sayuran dan buah- buahan merupakan sumber terbaik berbagai vitamin, mineral dan serat. Menurut World Health Organization (WHO), lansia adalah seseorang yang telah memasuki usia 60 tahun ke atas. Di Indonesia mengalami peningkatan jumlah penduduk lansia 18 juta jiwa (7,56 %) pada tahun 2010 menjadi 25,9 juta jiwa (9,7%) pada tahun 2019 dan dapat diperkirakan akan terus meningkat dimana tahun 2035 menjadi 48,2 juta jiwa (15,77%). Lansia memerlukan berbagai macam makanan untuk menjaga keseimbangan gizi, salah satunya untuk menghindari penyakit menular (misal infeksi) dan penyakit tidak menular (misal hipertensi). Lansia secara prinsip sangat memerlukan perlindungan dan pemberian informasi yang benar pada masa pandemik, terutama terkait penjagaan kesehatan mental dan fisik. Menurut data statistik daerah kabupaten kepulauan seribu tahun 2021 terdiri dari 2 kecamatan dan 6 kelurahan. Selama kurun waktu 1 tahun (2019 – 2020), penduduk Kepulauan Seribu mengalami kenaikkan 1,56 persen. Jika dilihat dari penduduk menurut kelompok umur terlihat bahwa komposisi usia produktif (15-64 tahun) hampir dua kali lipat usia tidak produktif ( > 64 tahun/ lansia) yaitu sebesar 66,82 persen. Oleh karena itu, pada kegiatan pengabdian kepada masyarakat (PKM), kami ingin melakukan Penyuluhan Vitamin dan Supplemen Makanan yang dibutuhkan tubuh untuk Lansia (usia diatas 60 Tahun) di Kelurahan P. Tidung, Pulau Seribu pada tanggal 17-19 Juni 2022. Kata Kunci : Pengabdian kepada Masyarakat, Vitamin dan Supplemen, Lansia, Pandemic Covid-19. / The COVID-19 (coronavirus) pandemic has caused many changes in daily life. Good nutrition is very important before, during and after infection. Adequate nutrition, especially vitamins and minerals, is needed in maintaining an optimal immune system, vegetables and fruits are the best sources of various vitamins, minerals and fiber. According to the World Health Organization (WHO), the elderly is someone who has entered the age of 60 years and over. In Indonesia, the number of elderly people increased from 18 million people (7.56%) in 2010 to 25.9 million people (9.7%) in 2019 and can be expected to continue to increase where in 2035 to 48.2 million people (15,77%). The elderly need a variety of foods to maintain a nutritional balance, one of which is to avoid infectious diseases (eg infections) and non-communicable diseases (eg hypertension). In principle, the elderly really need protection and the provision of correct information during a pandemic, especially regarding mental and physical health care. According to statistical data, the Thousand Islands Regency in 2021 consists of 2 sub-districts and 6 urban villages. During the period of 1 year (2019 – 2020), the population of the Thousand Islands experienced an increase of 1.56 percent. If we look at the population by age group, it can be seen that the composition of productive age (15-64 years) is almost double the unproductive age (> 64 years/elderly) which is 66.82 percent. Therefore, in community service activities (PKM), we want to do Vitamin and Food Supplement Counseling for the elderly (over 60 years old) in P. Tidung Village, Pulau Seribu on 17-19 June 2022. Keywords: Community Service; Vitamin and Supplement; elderly; The Covid-19 Pandemic