365 research outputs found
Energy-Efficient Optimization for Wireless Information and Power Transfer in Large-Scale MIMO Systems Employing Energy Beamforming
In this letter, we consider a large-scale multiple-input multiple-output
(MIMO) system where the receiver should harvest energy from the transmitter by
wireless power transfer to support its wireless information transmission. The
energy beamforming in the large-scale MIMO system is utilized to address the
challenging problem of long-distance wireless power transfer. Furthermore,
considering the limitation of the power in such a system, this letter focuses
on the maximization of the energy efficiency of information transmission (bit
per Joule) while satisfying the quality-of-service (QoS) requirement, i.e.
delay constraint, by jointly optimizing transfer duration and transmit power.
By solving the optimization problem, we derive an energy-efficient resource
allocation scheme. Numerical results validate the effectiveness of the proposed
scheme.Comment: 4 pages, 3 figures. IEEE Wireless Communications Letters 201
Demand Shaping to Achieve Steady Electricity Consumption with Load Balancing in a Smart Grid
The purpose of this paper is to study conflicting objectives between the grid
operator and consumers in a future smart grid. Traditionally, customers in
electricity grids have different demand profiles and it is generally assumed
that the grid has to match and satisfy the demand profiles of all its users.
However, for system operators and electricity producers, it is usually most
desirable, convenient and cost effective to keep electricity production at a
constant rate. The temporal variability of electricity demand forces power
generators, especially load following and peaking plants to constantly
manipulate electricity production away from a steady operating point
Protective effect of astragalus injection against myocardial injury in septic young rats via inhibition of JAK/STAT signal pathway and regulation of inflammation
Purpose: To investigate the protective effect of astragalus injection against myocardial injury in septic young rats, and the underlying mechanism of action.
Methods: Seventy-two healthy Sprague Dawley (SD) rats were randomly selected and used to establish a young rat model of sepsis. The young rats were randomly divided into 3 groups: sham, model and astragalus injection groups. Each group had 24 young rats. Serum cardiac troponin I (cTnI), IL-10, IL-6, JAK2 and STAT3 were measured after op.
Results: Compared with sham group, serum cTnI level in the model group was significantly higher, while serum cTnI level of the drug group was significantly lower than that of the model group (p < 0.05). Compared with model group, the level of IL-10 in the myocardial tissue of the drug group was significantly elevated, while IL-6 level was lower (p < 0.05). Relative to sham rats, myocardial JAK2 and STAT3 protein levels in model rats were high. However, myocardial JAK2 and STAT3 proteins in the drug-treated rats were significantly downregulated, relative to model rats (p < 0.05).
Conclusion: Astragalus injection upregulates IL-10 and IL-6 in rats by inhibiting the activation of JAK/STAT signal pathway, and via maintenance of pro-inflammation/anti-inflammation balance. Thus, astragalus exerts protective effect against myocardial injury in sepsis, and can potentially be developed for use as such in clinical practice.
Keywords: Astragalus injection, JAK/STAT signal pathway, Pro-inflammatory/anti-inflammatory imbalance, Sepsis, Myocardial injur
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