Wideband high efficiency optical modulator Final report, 15 Feb. 1966 - 15 Mar. 1967

Design of wideband high efficiency optical modulation system tested over 100-MHz ban

Letter from Thomas W. Bicknell to John Muir, 1896 Jul 9.

Linekin, Maine, July 9, 1896.My dear Sir:-I have mailed you a circular of our new Magazine, Suecess , to be published in August, in which I think you will be deeply interested. Its aims appeal to all friends of American youth for their sympathetic support, and a careful reading of the Foreword will give its scope and field of work.On behalf of its management, I take pleasure in inviting you to be a contributor to its pages, by one or more articles during the current year, for which we shall pay as generously as our Treasury will allow. I shall be glad to receive also a word of encouragement that we can use in our first number.Hoping to hear by very early mail of your willingness to contribute of your valuable thought and life experiences for the benefit of our young men and women,I am, most truly, Summer Home

The fish fauna of the Iwokrama Forest

Fishes were collected from the rivers in and around the Iwokrama Forest during January-February and November-December 1997. Four hundred species of fish were recorded from forty families in ten orders. Many of these fishes are newly recorded from Guyana and several are thought to be endemic. The number of species recorded for the area is surprising given the low level of effort and suggests that this area may be particularly important from a fish diversity perspective. This paper focuses on species of particular interest from a management perspective including those considered economically important, rare or endangered. The paper is also the basis for developing fisheries management systems in the Iwokrama Forest and Rupununi Wetlands

A remark on the trace-map for the Silver mean sequence

In this work we study the Silver mean sequence based on substitution rules by means of a transfer-matrix approach. Using transfer-matrix method we find a recurrence relation for the traces of general transfer-matrices which characterizes electronic properties of the quasicrystal in question. We also find an invariant of the trace-map.Comment: 5 pages, minor improvements in style and presentation of calculation

1863-02-14 Adjutant Bicknell recommends William Fenderson for promotion

https://digitalmaine.com/cw_me_5th_regiment_corr/1495/thumbnail.jp

Spatially Resolved Far-Ultraviolet Spectroscopy of the Nuclear Region of NGC 1068

We carry out high-resolution FUSE spectroscopy of the nuclear region of NGC 1068. The first set of spectra was obtained with a 30" square aperture that collects all emission from the narrow-line region. The data reveal a strong broad OVI component of FWHM ~3500 kms-1 and two narrow OVI 1031/1037 components of ~350 kms-1. The CIII 977 and NIII 991 emission lines in this spectrum can be fitted with a narrow component of FWHM ~1000 kms-1 and a broad one of ~2500 kms-1. Another set of seven spatially resolved spectra were made using a long slit of 1.25" X 20", at steps of ~1" along the axis of the emission-line cone. We find that (1) Major emission lines in the FUSE wavelength range consist of a broad and a narrow component; (2) There is a gradient in the velocity field for the narrow OVI component of ~200 kms-1 from ~2" southwest of the nucleus to ~4" northeast. A similar pattern is also observed with the broad OVI component, with a gradient of ~3000 kms-1. These are consistent with the HST/STIS findings and suggest a biconical structure in which the velocity field is mainly radial outflow; (3) A major portion of the CIII and NIII line flux is produced in the compact core. They are therefore not effective temperature diagnostics for the conical region; and (4) The best-fitted UV continuum suggests virtually no reddening, and the HeII 1085/1640 ratio suggests a consistently low extinction factor across the cone.Comment: To appear in the Astrophysical Journal. 37 pages with 12 figure

Equation of state and transport processes in self--similar spheres

We study the effect of transport processes (diffusion and free--streaming) on a collapsing spherically symmetric distribution of matter in a self--similar space--time. A very simple solution shows interesting features when it is matched with the Vaidya exterior solution. In the mixed case (diffusion and free--streaming), we find a barotropic equation of state in the stationary regime. In the diffusion approximation the gravitational potential at the surface is always constant; if we perturb the stationary state, the system is very stable, recovering the barotropic equation of state as time progresses. In the free--streaming case the self--similar evolution is stationary but with a non--barotropic equation of state.Comment: 9 pages, 2 figure

Gene signatures in wound tissue as evidenced by molecular profiling in the chick embryo model

<p>Abstract</p> <p>Background</p> <p>Modern functional genomic approaches may help to better understand the molecular events involved in tissue morphogenesis and to identify molecular signatures and pathways. We have recently applied transcriptomic profiling to evidence molecular signatures in the development of the normal chicken chorioallantoic membrane (CAM) and in tumor engrafted on the CAM. We have now extended our studies by performing a transcriptome analysis in the "wound model" of the chicken CAM, which is another relevant model of tissue morphogenesis.</p> <p>Results</p> <p>To induce granulation tissue (GT) formation, we performed wounding of the chicken CAM and compared gene expression to normal CAM at the same stage of development. Matched control samples from the same individual were used. We observed a total of 282 genes up-regulated and 44 genes down-regulated assuming a false-discovery rate at 5% and a fold change > 2. Furthermore, bioinformatics analysis lead to the identification of several categories that are associated to organismal injury, tissue morphology, cellular movement, inflammatory disease, development and immune system. Endothelial cell data filtering leads to the identification of several new genes with an endothelial cell signature.</p> <p>Conclusions</p> <p>The chick chorioallantoic wound model allows the identification of gene signatures and pathways involved in GT formation and neoangiogenesis. This may constitute a fertile ground for further studies.</p

A relativistic model of the radio jets in NGC 315

We apply our intrinsically symmetrical, decelerating relativistic jet model to deep VLA imaging of the inner 140 arcsec of the giant low-luminosity radio galaxy NGC 315. An optimized model accurately fits the data in both total intensity and linear polarization. We infer that the velocity, emissivity and field structure in NGC 315 are very similar to those of the other low-luminosity sources we have modelled, but that all of the physical scales are larger by a factor of about 5. We derive an inclination to the line of sight of 38 degrees for the jets. Where they first brighten, their on-axis velocity is approximately v/c = 0.9. They decelerate to v/c = 0.4 between 8 and 18 kpc from the nucleus and the velocity thereafter remains constant. The speed at the edge of the jet is roughly 0.6 of the on-axis value where it is best constrained, but the transverse velocity profile may deviate systematically from the Gaussian form we assume. The proper emissivity profile is split into three power-law regions separated by shorter transition zones. In the first of these, at 3 kpc (the flaring point) the jets expand rapidly at constant emissivity, leading to a large increase in the observed brightness on the approaching side. At 10 kpc, the emissivity drops abruptly by a factor of 2. Where the jets are well resolved their rest-frame emission is centre-brightened. The magnetic field is modelled as random on small scales but anisotropic and we rule out a globally ordered helical configuration. To a first approximation, the field evolves from a mixture of longitudinal and toroidal components to predominantly toroidal, but it also shows variations in structure along and across the jets, with a significant radial component in places. Simple adiabatic models fail to fit the emissivity variations.Comment: 20 pages, 17 figures, MNRAS (in press

Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression

Vascular endothelial growth factor (VEGF) is an important factor mediating tumour angiogenesis. VEGF mRNA is differentially expressed in bladder cancer with high expression in superficial tumours (stage pTaand pT1) contrasting with low expression in muscle invasive tumours (stage ≥ pT2). To investigate mechanisms regulating VEGF expression in bladder cancer, VEGF mRNA and protein were measured in normal bladder (n = 12) and primary bladder cancers (n = 57). VEGF protein levels correlated with mRNA expression in normal bladder (r = 0.68, P = 0.02) and bladder cancer (r = 0.46, P = 0.0007). Whilst VEGF mRNA expression was threefold higher in superficial compared to muscle invasive bladder cancers (P = 0.0001) there was no difference in VEGF protein (P = 0.81). Accordingly, the median protein:mRNA ratios increased more than 15-fold with increasing tumour stage (P< 0.0001) suggesting translational regulation. Expression of the eukaryotic initiation factor-4E (eIF-4E), a factor implicated in the translational regulation of VEGF, was greater in tumours than normal bladder (P< 0.0001) and correlated with VEGF protein:mRNA ratios (n = 43, r = 0.54, P = 0.0004) pointing to its role in the regulation of VEGF. In superficial tumours (n = 37) high expression of eIF-4E was associated with a poor prognosis and reduced stage progression-free survival (P = 0.04, Cox proportional hazards model). The study demonstrates that eIF-4E may be involved in translational regulation of VEGF in bladder cancer and might have a role as a prognostic factor in bladder cancer. © 2000 Cancer Research Campaig