198 research outputs found
Level Crossing Rate and Average Fade Duration of the Multihop Rayleigh Fading Channel
We present a novel analytical framework for the evaluation of important
second order statistical parameters, as the level crossing rate (LCR) and the
average fade duration (AFD) of the amplify-and-forward multihop Rayleigh fading
channel. More specifically, motivated by the fact that this channel is a
cascaded one, which can be modelled as the product of N fading amplitudes, we
derive novel analytical expressions for the average LCR and AFD of the product
of N Rayleigh fading envelopes, or of the recently so-called N*Rayleigh
channel. Furthermore, we derive simple and efficient closed-form approximations
to the aforementioned parameters, using the multivariate Laplace approximation
theorem. It is shown that our general results reduce to the specific dual-hop
case, previously published. Numerical and computer simulation examples verify
the accuracy of the presented mathematical analysis and show the tightness of
the proposed approximations
An Accurate Approximation to the Distribution of the Sum of Equally Correlated Nakagami-m Envelopes and its Application in Equal Gain Diversity Receivers
We present a novel and accurate approximation for the distribution of the sum
of equally correlated Nakagami-m variates. Ascertaining on this result we study
the performance of Equal Gain Combining (EGC) receivers, operating over equally
correlating fading channels. Numerical results and simulations show the
accuracy of the proposed approximation and the validity of the mathematical
analysis
On the Second Order Statistics of the Multihop Rayleigh Fading Channel
Second order statistics provides a dynamic representation of a fading channel
and plays an important role in the evaluation and design of the wireless
communication systems. In this paper, we present a novel analytical framework
for the evaluation of important second order statistical parameters, as the
level crossing rate (LCR) and the average fade duration (AFD) of the
amplify-and-forward multihop Rayleigh fading channel. More specifically,
motivated by the fact that this channel is a cascaded one and can be modeled as
the product of N fading amplitudes, we derive novel analytical expressions for
the average LCR and the AFD of the product of N Rayleigh fading envelopes (or
of the recently so-called N*Rayleigh channel). Furthermore, we derive simple
and efficient closed-form approximations to the aforementioned parameters,
using the multivariate Laplace approximation theorem. It is shown that our
general results reduce to the corresponding ones of the specific dual-hop case,
previously published. Numerical and computer simulation examples verify the
accuracy of the presented mathematical analysis and show the tightness of the
proposed approximations
Wireless Networks with Energy Harvesting and Power Transfer: Joint Power and Time Allocation
In this paper, we consider wireless powered communication networks which
could operate perpetually, as the base station (BS) broadcasts energy to the
multiple energy harvesting (EH) information transmitters. These employ "harvest
then transmit" mechanism, as they spend all of their energy harvested during
the previous BS energy broadcast to transmit the information towards the BS.
Assuming time division multiple access (TDMA), we propose a novel transmission
scheme for jointly optimal allocation of the BS broadcasting power and time
sharing among the wireless nodes, which maximizes the overall network
throughput, under the constraint of average transmit power and maximum transmit
power at the BS. The proposed scheme significantly outperforms "state of the
art" schemes that employ only the optimal time allocation. If a single EH
transmitter is considered, we generalize the optimal solutions for the case of
fixed circuit power consumption, which refers to a much more practical
scenario.Comment: 5 pages, 2 figures in IEEE Signal Processing Letters, vol. 23, no. 1,
January 201
Level Crossing Rate and Average Fade Duration of the Double Nakagami-m Random Process and Application in MIMO Keyhole Fading Channels
We present novel exact expressions and accurate closed-form approximations
for the level crossing rate (LCR) and the average fade duration (AFD) of the
double Nakagami-m random process. These results are then used to study the
second order statistics of multiple input multiple output (MIMO) keyhole fading
channels with space-time block coding. Numerical and computer simulation
examples validate the accuracy of the presented mathematical analysis and show
the tightness of the proposed approximations
Cooperative Diversity with Mobile Nodes: Capacity Outage Rate and Duration
The outage probability is an important performance measure for cooperative
diversity schemes. However, in mobile environments, the outage probability does
not completely describe the behavior of cooperative diversity schemes since the
mobility of the involved nodes introduces variations in the channel gains. As a
result, the capacity outage events are correlated in time and second-order
statistical parameters of the achievable information-theoretic capacity such as
the average capacity outage rate (AOR) and the average capacity outage duration
(AOD) are required to obtain a more complete description of the properties of
cooperative diversity protocols. In this paper, assuming slow Rayleigh fading,
we derive exact expressions for the AOR and the AOD of three well-known
cooperative diversity protocols: variable-gain amplify-and-forward,
decode-and-forward, and selection decode-and-forward relaying. Furthermore, we
develop asymptotically tight high signal-to-noise ratio (SNR) approximations,
which offer important insights into the influence of various system and channel
parameters on the AOR and AOD. In particular, we show that on a
double-logarithmic scale, similar to the outage probability, the AOR
asymptotically decays with the SNR with a slope that depends on the diversity
gain of the cooperative protocol, whereas the AOD asymptotically decays with a
slope of -1/2 independent of the diversity gain.Comment: IEEE Transactions on Information Theory (2011
Traffic agents for improving QoS in mixed infrastructure and ad hoc modes wireless LAN
As an important complement to infrastructured wireless networks, mobile ad hoc networks (MANET) are more flexible in providing wireless access services, but more difficult in meeting different quality of service (QoS) requirements for mobile customers. Both infrastructure and ad hoc network structures are supported in wireless local area networks (WLAN), which can offer high data-rate wireless multimedia services to the mobile stations (MSs) in a limited geographical area. For those out-of-coverage MSs, how to effectively connect them to the access point (AP) and provide QoS support is a challenging issue. By mixing the infrastructure and the ad hoc modes in WLAN, we propose in this paper a new coverage improvement scheme that can identify suitable idle MSs in good service zones as traffic agents (TAs) to relay traffic from those out-of-coverage MSs to the AP. The service coverage area of WLAN is then expanded. The QoS requirements (e.g., bandwidth) of those MSs are considered in the selection process of corresponding TAs. Mathematical analysis, verified by computer simulations, shows that the proposed TA scheme can effectively reduce blocking probability when traffic load is light
Insights Into Patient Variability During Ivacaftor-Lumacaftor Therapy in Cystic Fibrosis
Background: The advent of cystic fibrosis transmembrane conductance regulator protein (CFTR) modulators like ivacaftor have revolutionised the treatment of cystic fibrosis (CF). However, due to the plethora of variances in disease manifestations in CF, there are inherent challenges in unified responses under CFTR modulator treatment arising from variability in patient outcomes. The pharmacokinetic (PK) data available for ivacaftor-lumacaftor cystic fibrosis (CF) transmembrane conductance regulator (CFTR) modulator drug combination is limited.
Methods: Secondary objectives were to identify (1) patient characteristics and (2) the interactions between ivacaftor-lumacaftor responsible for interindividual variability (IIV).
Results: Peak plasma concentrations (Cmax) of ivacaftor - lumacaftor were >10 fold lower than expected compared to label information. The one-way ANOVA indicated that the patient site had an effect on Cmax values of ivacaftor metabolites ivacaftor-M1, ivacaftor-M6, and lumacaftor (p < 0.001, p < 0.001, and p < 0.001, respectively). The Spearman’s rho test indicated that patient weight and age have an effect on the Cmax of lumacaftor (p = 0.003 and p < 0.001, respectively) and ivacaftor metabolite M1 (p = 0.020 and p < 0.001, respectively). Age (p < 0.001) was found to effect on Cmax of ivacaftor M6 and on Tmax of ivacaftor M1 (p = 0.026). A large impact of patient characteristics on the IIV of PK parameters Cmax and Tmax, was observed among the CF patients.
Conclusion: Understanding the many sources of variability can help reduce this individual patient variability and ensure consistent patient outcomes
Propagation of Neutron Cross Section, Fission Yield, and Decay Data Uncertainties in Depletion Calculations
Propagation of nuclear data uncertainties in reactor calculations is interesting for design purposes and libraries evaluation. Previous versions of the GRS XSUSA library propagated only neutron cross section uncertainties. We have extended XSUSA uncertainty assessment capabilities by including propagation of fission yields and decay data uncertainties due to the their relevance in depletion simulations. We apply this extended methodology to the UAM6 PWR Pin-Cell Burnup Benchmark, which involves uncertainty propagation through burnup
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