Data synthesis for crop variety evaluation. A review

Crop varieties should fulfill multiple requirements, including agronomic performance and product quality. Variety evaluations depend on data generated from field trials and sensory analyses, performed with different levels of participation from farmers and consumers. Such multi-faceted variety evaluation is expensive and time-consuming; hence, any use of these data should be optimized. Data synthesis can help to take advantage of existing and new data, combining data from different sources and combining it with expert knowledge to produce new information and understanding that supports decision-making. Data synthesis for crop variety evaluation can partly build on extant experiences and methods, but it also requires methodological innovation. We review the elements required to achieve data synthesis for crop variety evaluation, including (1) data types required for crop variety evaluation, (2) main challenges in data management and integration, (3) main global initiatives aiming to solve those challenges, (4) current statistical approaches to combine data for crop variety evaluation and (5) existing data synthesis methods used in evaluation of varieties to combine different datasets from multiple data sources. We conclude that currently available methods have the potential to overcome existing barriers to data synthesis and could set in motion a virtuous cycle that will encourage researchers to share data and collaborate on data-driven research

Gender-Disaggregated Seasonal and Daily Calendars of Farmers in Uganda and Tanzania

This report discusses the agricultural activities (seasonal, weekly, and daily) that take place in a typical year to provide insight into men’s and women’s perceptions of the seasons, agricultural activities, crops grown, and sex-disaggregated division of labor related to those crops and activities performed during specific times in a day or week in selected regions of Uganda and Tanzania. Qualitative data were collected from 38 sex-disaggregated focus group discussions (FGDs) conducted with a total of 341 participants. Sixteen FGDs consisted of men only and 22 consisted of women only

Gender and trait preferences for banana cultivation and use in Sub-Saharan Africa: A literature review

Understanding trait preferences of different actors in the banana value chain may facilitate the selection and adoption of new cultivars. We systematically reviewed the scholarly and gray literature on banana trait preferences, with specific attention to studies that document gender-differentiated traits. Of 44 publications reviewed, only four reported gender-specific trait preferences, indicating a significant gap in the literature. The review found that banana farmers, irrespective of gender, value similar characteristics that are related to production constraints, income enhancement, consumption, and cultural or ritual uses. Farmers (as producers, processors, and consumers) often prefer traditional cultivars because of their superior consumption attributes, even if new cultivars have better agronomic and host plant resistance characteristics. Potential differences between trait preferences of farmers and other actors in the value chain should be accounted for to enhance marketing potential. Gender-specific research along the banana value chain and engaging users at the initial stages of breeding can ensure that new cultivars are acceptable to users and may improve adoption. Interdisciplinary teamwork is essential for an efficient and effective breeding program

Benefit of adjuvant chemotherapy on recurrence free survival per consensus molecular subtype in stage III colon cancer

The consensus molecular subtype (CMS) classification divides colon tumors into four subtypes holding promise as a predictive biomarker. However, the effect of adjuvant chemotherapy on recurrence free survival (RFS) per CMS in stage III patients remains inadequately explored. With this intention, we selected stage III colon cancer (CC) patients from the MATCH cohort (n = 575) and RadboudUMC (n = 276) diagnosed between 2005 and 2018. Patients treated with and without adjuvant chemotherapy were matched based on tumor location, T- and N-stage (n = 522). Tumor material was available for 464 patients, with successful RNA extraction and CMS subtyping achieved in 390 patients (surgery alone group: 192, adjuvant chemotherapy group: 198). In the overall cohort, CMS4 was associated with poorest prognosis (HR 1.55; p =.03). Multivariate analysis revealed favorable RFS for the adjuvant chemotherapy group in CMS1, CMS2, and CMS4 tumors (HR 0.19; p =.01, HR 0.27; p &lt;.01, HR 0.19; p &lt;.01, respectively), while no significant difference between treatment groups was observed within CMS3 (HR 0.68; p =.51). CMS subtyping in this non-randomized cohort identified patients with poor prognosis and patients who may not benefit significantly from adjuvant chemotherapy.</p

Gender-Disaggregated Seasonal and Daily Calendars of Farmers in Uganda and Tanzania

This report discusses the agricultural activities (seasonal, weekly, and daily) that take place in a typical year to provide insight into men’s and women’s perceptions of the seasons, agricultural activities, crops grown, and sex-disaggregated division of labor related to those crops and activities performed during specific times in a day or week in selected regions of Uganda and Tanzania. Qualitative data were collected from 38 sex-disaggregated focus group discussions (FGDs) conducted with a total of 341 participants. Sixteen FGDs consisted of men only and 22 consisted of women only. Research was conducted in two districts in Uganda (Luweero in the Central Region and Mbarara in the Western Region) and four districts in Tanzania – Meru in Arusha Region, Moshi in Kilimanjaro (Northeastern zone), Rungwe in Mbeya Region (Southern Highland zone), and Bukoba in Kagera Region (Northwestern zone). Agriculture was the main occupation for the participants in both countries. The ten most commonly grown crops across all districts included banana, maize, beans, coffee, sweet potatoes, cassava, groundnuts, and vegetables (including leafy greens), with banana being ranked as the most important crop in both countries. Maize and beans were mostly emphasized by women as important food and cash crops. The ranking of crop importance provides insight into what participants viewed as important for meeting household subsistence needs as well as providing cash income. The month of March was reported as the start of the farming season by most FGDs, with peak rainfall occurring in April and November. Peak sunshine occurred in July and January/ February. There were also some slight seasonal variations across the different districts in the timing and types of cropping activities. For instance, most sweet potato activity takes place during the rainy season, while for beans and banana, two peaks of activities occur, one in the rainy season and one in the dry season. Coffee activities increase and decrease when bean and banana activities decrease and increase, respectively, indicating when labor can be transferred between these crops. The division of labor by men and women showed that cropping activities for banana were mostly done by men as they spent more labor on banana than on other crops. As such, banana was regarded as a men’s crop. These activities, which include land preparation, procuring planting material, and digging holes and trenches, were not specific to a banana usage type (e.g., dessert, cooking, beer). Similar to banana, coffee was considered a cash and men’s crop, as men undertake most (72%) of the cultivation activities. Maize production activities were undertaken by 59% women and 41% men, while women undertook most (81%) of the bean production activities. The types of activities done over a week in busy and quiet months, for instance, home activities, child care, and farm work, occurred consistently across the week. Some activities took place on specific days of the week such as worship in mosques or churches. Sunday was reported as a specific rest day. Home, farming, and livestock activities occur throughout the year regardless of the season. Daily activities such as those done around the home (e.g., food preparation) were consistently undertaken regardless of the season (busy or quiet). Daily activities differed between men and women. While men reported more time spent bresting and socializing than women on both busy and quiet days, women reported more time in food preparation, child care, and home activities (which include cleaning but also making handicrafts or other income-generating activities

Gender-disaggregated seasonal and daily calendars of farmers in Uganda and Tanzania

This report discusses the agricultural activities (seasonal, weekly, and daily) that take place in a typical year to provide insight into men’s and women’s perceptions of the seasons, agricultural activities, crops grown, and sex-disaggregated division of labor related to those crops and activities performed during specific times in a day or week in selected regions of Uganda and Tanzania. Qualitative data were collected from 38 sex-disaggregated focus group discussions (FGDs) conducted with a total of 341 participants. Sixteen FGDs consisted of men only and 22 consisted of women only

Symptomatic Skeletal Events and the Use of Bone Health Agents in a Real-World Treated Metastatic Castration Resistant Prostate Cancer Population:Results From the CAPRI-Study in the Netherlands

Background: Patients with metastatic castration resistant prostate cancer (mCRPC) are at risk of symptomatic skeletal events (SSE). Bone health agents (BHA, ie bisphosphonates and denosumab) and new life-prolonging drugs (LPDs) can delay SSEs. The aim of this study is to investigate the use of BHAs in relation to SSEs in treated real-world mCRPC population. Patients and Methods: We included patients from the CAPRI registry who were treated with at least one LPD and diagnosed with bone metastases prior to the start of first LPD (LPD1). Outcomes were SSEs (external beam radiation therapy (EBRT) to the bone, orthopedic surgery, pathologic fracture or spinal cord compression) and SSE-free survival (SSE-FS) since LPD1. Results: One-thousand nine hundred and twenty-three patients were included with a median follow-up from LPD1 of 16.7 months. Fifty-two percent (n = 996) started BHA prior or within 4 weeks after the start of LPD1 (early BHA). In total, 41% experienced at least one SSE. SSE incidence rate was 0.29 per patient year for patients without BHA and 0.27 for patients with early BHA. Median SSE-FS from LPD1 was 12.9 months. SSE-FS was longer in patients who started BHA early versus patients without BHA (13.2 vs. 11.0 months, P =.001). Conclusion: In a real-world population we observed an undertreatment with BHAs, although patients with early BHA use had lower incidence rates of SSEs and longer SSE-FS. This finding was irrespective of type of SSE and presence of risk factors. In addition to LPD treatment, timely initiation of BHAs is recommended in bone metastatic CRPC-patients with both pain and/or opioid use and prior SSE

Post-harvest use of banana in Uganda and Tanzania: Product characteristics and cultivar preferences of male and female farmers.

Understanding user preferred traits is important for the successful development and adoption of improved banana cultivars. This article provides an overview of different banana products, cultivars used to make those products and the preferred characteristics as reported by men and women farmers in different regions of Uganda and Tanzania. Qualitative data from 23 focus group discussions (FGDs) conducted in six districts (Mbarara and Luwero in Uganda; and Bukoba, Meru, Moshi and Rungwe in Tanzania) were coded and analysed. Results show that farmers process banana to make a range of products that include staple foods such as steamed matooke, mbalaga and machalari; alcoholic beverages and snacks. Different cultivars are preferred for an assortment of products. There are minimal differences in the cultivar preferences for specific products and product utilization patterns by men and women farmers. Differences only occurred when men and women described reasons why products are important or preferred, and in the roles of men, women and children in the preparation and processing of products from different banana types. Both men and women mentioned socio-economic, cultural, consumption and health-related attributes of the different products. However, women (73% of women only FGDs) specifically highlighted health benefits attached to women, for example after giving birth, during pregnancy, during lactation and for children; compared to 44% for men. Men pointed out more the socio-cultural importance of the products and provided detailed descriptions on market-related traits and the corresponding value chain actors (88.9% of men only FGDs). A myriad of factors that include variety of products, cultivar attributes before processing, characteristics of the processed product and location differences are identified, highlighting the need for further assessments and physicochemical characterisation of the traits to gauge the feasibility of considering this valuable information in the product development process. Some of the products and attributes of cultivars cited by farmers are generalized descriptions lacking sufficient detail (e.g. ‘tastes nice’, ‘good flavour’, ‘long shelf life’). Farmers have tacit knowledge of these attributes. Hence, researchers need to probe further and use a range of methods to extract this knowledge. There is a need for social scientists to collect data on trait prioritisation and for food scientists to do biochemical analyses to ensure information collected is well defined, comprehensive, quantifiable and measurable to effectively guide breeding and other agricultural research and development