Structural behaviour and strain distribution of the long bones of the human lower limbs

n/

Use of embedded strain gages for the in-vitro study of proximal tibial cancellous bone deformation during knee flexion-extension movement: development, reproducibility and preliminary results of feasibility after frontal low femoral osteotomy

<p>Abstract</p> <p>Background</p> <p>This paper reports the development of an in-vitro technique allowing quantification of relative (not absolute) deformations measured at the level of the cancellous bone of the tibial proximal epiphysis (CB_TPE) during knee flexion-extension. This method has been developed to allow a future study of the effects of low femoral osteotomies consequence on the CB_TPE.</p> <p>Methods</p> <p>Six strain gages were encapsulated in an epoxy resin solution to form, after resin polymerisation, six measurement elements (ME). The latter were inserted into the CB_TPEof six unembalmed specimens, just below the tibial plateau. Knee motion data were collected by three-dimensional (3D) electrogoniometry during several cycles of knee flexion-extension. Intra- and inter-observer reproducibility was estimated on one specimen for all MEs. Intra-specimen repeatability was calculated to determine specimen's variability and the error of measurement. A varum and valgum chirurgical procedure was realised on another specimen to observed CB_TPEdeformation after these kind of procedure.</p> <p>Results</p> <p>Average intra-observer variation of the deformation ranged from 8% to 9% (mean coefficient of variation, MCV) respectively for extension and flexion movement. The coefficient of multiple correlations (CMC) ranged from 0.93 to 0.96 for flexion and extension. No phase shift of maximum strain peaks was observed. Inter-observer MCV averaged 23% and 28% for flexion and extension. The CMC were 0.82 and 0.87 respectively for extension and flexion. For the intra-specimen repeatability, the average of mean RMS difference and the mean ICC were calculated only for flexion movement. The mean RMS variability ranged from 7 to 10% and the mean ICC was 0.98 (0.95 - 0.99). A Pearson's correlation coefficient was calculated showing that RMS was independent of signal intensity. For the chirurgical procedure, valgum and varum deviation seems be in agree with the frontal misalignment theory.</p> <p>Conclusions</p> <p>Results show that the methodology is reproducible within a range of 10%. This method has been developed to allow analysis the indirect reflect of deformation variations in CB_TPEbefore and after distal femoral osteotomies. The first results of the valgum and varum deformation show that our methodology allows this kind of measurement and are encourageant for latter studies. It will therefore allow quantification and enhance the understanding of the effects of this kind of surgery on the CB_TPEloading.</p

Advanced data customization pipeline for motion analysis and modeling

0info:eu-repo/semantics/publishe

The Virtual Physiological Human Network of Excellence (VPH-NoE)

info:eu-repo/semantics/publishe

Technical Report on Registration for Animated Models

info:eu-repo/semantics/publishe

Pedagogical Validation of Multimodal Display

info:eu-repo/semantics/publishe

Final Report

info:eu-repo/semantics/publishe

Towards an advanced clinical expert system for patient-specific modelling and musculo-skeletal (MS) analysis?

info:eu-repo/semantics/publishe

Modelling of the musculoskeletal system and its physiology :scientific and clinical applications

info:eu-repo/semantics/publishe

Participation à l’écriture d’un « Roadmap » pour la Commission Européenne dans le cadre de l’appel à projets (Programme-cadre 7): « Seeding the EuroPhysiome :a Roadmap to the Physiological Physiological Human »

Téléchargeable à partir de http://www.europhysiome.org/info:eu-repo/semantics/publishe