666 research outputs found

    Strenghtening Protections for Survivors of Domestic Violence: The Case of Washington, D.C.

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    Certain minimal varieties are set-theoretic complete intersections

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    We present a class of homogeneous ideals which are generated by monomials and binomials of degree two and are set-theoretic complete intersections. This class includes certain reducible varieties of minimal degree and, in particular, the presentation ideals of the fiber cone algebras of monomial varieties of codimension two

    Peer choice in CEO compensation

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    Current research shows that firms are more likely to benchmark against peers that pay their Chief Executive Officers (CEOs) higher compensation, reflecting self serving behavior. We propose an alternative explanation: the choice of highly paid peers represents a reward for unobserved CEO talent. We test this hypothesis by decomposing the effect of peer selection into talent and self serving components. Consistent with our prediction, we find that the association between a firm's selection of highly paid peers and CEO pay mostly represents compensation for CEO talent

    Ultra-Stable and Robust Response to X-Rays in 2D Layered Perovskite Micro-Crystalline Films Directly Deposited on Flexible Substrate

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    2D layered hybrid perovskites have recently attracted an increasing interest as active layers in LEDs and UV–Vis photodetectors. 2D perovskites crystallize in a natural self-assembled quantum well-like structure and possess several interesting features among which low-temperature (<100 °C) synthesis and low defect density. Here are presented solid-state ionizing radiation direct detectors based on the 2D layered hybrid perovskite PEA2PbBr4 (PEA = C6H5C2H4NH3+) deposited from solution using scalable techniques and directly integrated onto a pre-patterned flexible substrate in the form of micro-crystalline films displaying crystal-like behavior, as evidenced by the ultra-fast (sub-microsecond) and good detection performances under UV light. The effective detection of X-rays (up to 150 kVp) is demonstrated with sensitivity values up to 806 ”C Gy−1 cm−2 and Limit of Detection of 42 nGy s−1, thus combining the excellent performance for two relevant figures of merit for solid-state detectors. Additionally, the tested devices exhibit exceptionally stable response under constant irradiation and bias, assessing the material robustness and the intimate electrical contact with the electrodes. PEA2PbBr4 micro-crystalline films directly grown on flexible pre-patterned substrate open the way for large-area solid-state detectors working at low radiation flux for ultra-fast X-ray imaging and dosimetry

    A role for NRAGE in NF-ÎșB activation through the non-canonical BMP pathway

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    <p>Abstract</p> <p>Background</p> <p>Previous studies have linked neurotrophin receptor-interacting MAGE protein to the bone morphogenic protein signaling pathway and its effect on p38 mediated apoptosis of neural progenitor cells via the XIAP-Tak1-Tab1 complex. Its effect on NF-ÎșB has yet to be explored.</p> <p>Results</p> <p>Herein we report that NRAGE, via the same XIAP-Tak1-Tab1 complex, is required for the phosphorylation of IKK -α/ÎČ and subsequent transcriptional activation of the p65 subunit of NF-ÎșB. Ablation of endogenous NRAGE by siRNA inhibited NF-ÎșB pathway activation, while ablation of Tak1 and Tab1 by morpholino inhibited overexpression of NRAGE from activating NF-ÎșB. Finally, cytokine profiling of an NRAGE over-expressing stable line revealed the expression of macrophage migration inhibitory factor.</p> <p>Conclusion</p> <p>Modulation of NRAGE expression revealed novel roles in regulating NF-ÎșB activity in the non-canonical bone morphogenic protein signaling pathway. The expression of macrophage migration inhibitory factor by bone morphogenic protein -4 reveals novel crosstalk between an immune cytokine and a developmental pathway.</p

    Rendimento e características agronÎmicas de soja em sistemas de produção com integração lavoura-pecuåria e diferentes manejos de solo.

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    Analisis Liabilitas dan Ekuitas terhadap Laba Operasional pada PT AlloBank Indonesia, Tbk

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    This research was conducted with the aim of analyzing whether the Liability and Equity factors affect Operational Profit at PT.Allo Bank Indonesia. In this analysis, using a quantitative approach which uses secondary data collected from the quarterly financial reports of PT. AlloBank Indonesia, Tbk. from 2015 to 2022. The data was analyzed using descriptive analysis techniques, multiple linear regression analysis, classical assumption tests, and hypothesis testing. The results of the study show that partially Liabilities do not have a significant effect while Equity has a positive relationship and has a significant effect on Operating Income. Taken together, the Liability and Equity Variables have a significant impact on operating profit with an adjusted R square of 10.3%. However, this study has limitations on the representativeness of the secondary data which will affect the results of the analysis so that for future researchers, it is advisable to use more complete data and consider the measurement of relevant additional variables. &nbsp
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