Properties of anti-corrosive ferrite pigment synthesized with the use of production waste

© 2018, International Multidisciplinary Scientific Geoconference. All rights reserved. Pigments of the inhibitory type are the active principle of most primers used to protect metals from corrosion. Developers of anticorrosive paint and varnish materials seek to replace chromium-containing pigments, which widely used until recently due to their toxicity, with more environmentally appropriate choices. These include ferrite pigments. It is known, that the most spread method for the synthesis of ferrites, which are complex oxides or salts of ferrous acid, is the joint calcination of iron oxides with oxides having basic properties. The aim of this work is an expansion of the raw material base to produce ferritic pigments by using as one of the initial components an aspiration dust (content of iron oxide exceeds 70 %) formed as a waste in steel-casting plants. Crushed brucite (natural magnesium oxide) was used as the second component. After their thorough mixing, the resulting mixture was calcined at the reaction temperature: MgО + Fe2O3 → MgFe2O4 (1) 6MgО + 4Fe3O4 + О2 → 6MgFe2O4 (2) with obtaining of magnesium ferrite. The course of the reaction was controlled by thermogravimetry and differential thermal analysis. Ferritic-magnetite structure formation was recorded by X-ray diffraction analysis. The variation of the synthesis’s temperature-time conditions made it possible to find the optimal parameters for obtaining ferrite. The synthesized ferrite was ground on a planetary mill. The studying of the painting and technical properties of the grinding product showed that it can be used as a pigment in the production of paints and varnishes. The results of electrochemical studies of steel in contact with the aqueous extract of ferritic pigment containing 3% of sodium chloride led to the conclusion of the high ability of the resulting product to inhibit the corrosion processes

The study of functional properties of drinking water «Evolet» on 3rd year students of medical and preventive faculty of the Ural state medical university

The purpose of the study is to analyze the influence of drinking water «Evolet» on the state of organism of 3-year students of medical and preventive faculty of USMU.Цель исследования. Проанализировать влияние питьевой воды «Evolet» на состояние организма студентов 3 курса медико- профилактического факультета УГМУ

Psychosocial components of patient compliance

This literature review reflects the current understanding of patient compliance as a general medical problem. The main psychosocial factors that improve or worsen compliance considered using examples of specific nosological forms. It shown that it is precisely in the satisfaction of the patient's motives that the key moment of the “doctor-patient” system consistency lies, without which it is impossible to build an adequate patient compliance to treatmentВ представленном литературном обзоре отражены современные представления о пациентском комплаенсе как общемедицинской проблеме. Рассмотрены основные психосоциальные факторы, улучшающие либо ухудшающие комплаенс, с приведением примеров конкретных нозологических форм. Показано, что именно в удовлетворении мотивов пациента лежит ключевой момент конгруэнтности системы «врач-пациент», без чего невозможно построение адекватного медикаментозного пациентского комплаенс

Eribulin-trastuzumab combination in HER2-positive metastatic breast cancer: updated results from a Russian observational study

Introduction. The standard of 1st line treatment of HER2+ metastatic breast cancer (mBC) is double blockade with trastuzumab and pertuzumab + taxane, 2nd line – Trastuzumab-emtazine. There are no standards for further treatment, as well as the optimal drug sequence. Expansion of the arsenal of therapeutic possibilities and the use of new combinations will certainly improve the results of treatment of this category of patients and increase their life expectancy.Aim. We sought to describe treatment patterns of  eribulin  and clinical outcomes of  metastatic HER2-positive breast cancer treated with eribulin  plus trastuzumab combination in  academic institutions and community oncology practices across the Russian Federation.Materials and methods. Patients treated with eribulin anytime between Jan, 2014 and Sep, 2019 with a diagnosis of MBC were identified by 23 providers from Russia. Providers retrospectively reviewed the health records and abstracted selected data points into an electronic case report form for each eligible patient.Results. 100 HER2-positive pts received eribulin in combination with trastuzumab. Median age was 55 (31–80) yrs and ECOG status 0–3. 67% pts had visceral metastases. Eribulin was administered as 1st and 2nd line to 23 (23%) pts, 3rd line to 31 (31%) pts, 4th line and later to 46 (46%). Median number of cycles was 5 (2–27). ORR was 12%, SD – 72%, SD > 6 months – 23%, PD – 16%. Clinical efficacy rate achieved in 35%. Median PFS was 5.07 months (95% CI 4.021–6.119). According to the ER-status the response to eribulin and trastuzumab was different. ORR was 18.8%, SD 72.9% in pts with ER-positive MBC (n = 48) and 5.8% and 71.2% respectively in ER-negative MBC (n = 52). Median PFS was 6.97 months (95% CI 3.924–10.016) in pts with ER-positive MBC and 4.67 months (95% CI 3.841–5.499) in ER-negative MBC (р = 0.3). The combination was well tolerated: dose reductions were required in 12% pts, withdrawal due to toxicity in 4% pts. The most common type of toxicity was hematological with neutropenia Gr III-IV in 14 (14%) pts. Peripheral neuropathy Gr III was observed in 5 (5%) pts. No cardiotoxicity was detected.Conclusions. This is the real-life data of clinical outcomes for patients receiving eribulin plus trastuzumab for HER2-positive MBC throughout the Russian Federation. Our experience with eribulin plus trastuzumab demonstrates that this combination may be a potential effective treatment option for HER-2 positive MBC patients

Integration Aspects of Using the ABC-method in Trade Organization

The recent crisis in Russia’s economy has resulted in noticeably decreased demand and increased competition. Under these conditions Russian companies were forced to pay closer attention to generation of management accounting information, the quality of which largely determines the effectiveness of their decisions. In its turn, improvement of the quality of information calls for modifying the standard methods or using the new methods of processing information such as “Activity-based costing” (ABC method). It should be noted that most articles describe the implementation of the ABC method by industrial enterprises, and only some papers focus on application of this method in trade. However, Western scientists consider the ABC method to be equally applicable to production and trade. Hence it becomes relevant to seek ways of implementing the ABC method in trade, taking into account its peculiarities, and what is more - to find the possibilities of integrating this method with the trade accounting data, which is the purpose of writing this article

Properties of anti-corrosive ferrite pigment synthesized with the use of production waste

© 2018, International Multidisciplinary Scientific Geoconference. All rights reserved. Pigments of the inhibitory type are the active principle of most primers used to protect metals from corrosion. Developers of anticorrosive paint and varnish materials seek to replace chromium-containing pigments, which widely used until recently due to their toxicity, with more environmentally appropriate choices. These include ferrite pigments. It is known, that the most spread method for the synthesis of ferrites, which are complex oxides or salts of ferrous acid, is the joint calcination of iron oxides with oxides having basic properties. The aim of this work is an expansion of the raw material base to produce ferritic pigments by using as one of the initial components an aspiration dust (content of iron oxide exceeds 70 %) formed as a waste in steel-casting plants. Crushed brucite (natural magnesium oxide) was used as the second component. After their thorough mixing, the resulting mixture was calcined at the reaction temperature: MgО + Fe2O3 → MgFe2O4 (1) 6MgО + 4Fe3O4 + О2 → 6MgFe2O4 (2) with obtaining of magnesium ferrite. The course of the reaction was controlled by thermogravimetry and differential thermal analysis. Ferritic-magnetite structure formation was recorded by X-ray diffraction analysis. The variation of the synthesis’s temperature-time conditions made it possible to find the optimal parameters for obtaining ferrite. The synthesized ferrite was ground on a planetary mill. The studying of the painting and technical properties of the grinding product showed that it can be used as a pigment in the production of paints and varnishes. The results of electrochemical studies of steel in contact with the aqueous extract of ferritic pigment containing 3% of sodium chloride led to the conclusion of the high ability of the resulting product to inhibit the corrosion processes

Non-linear M -sequences Generation Method

The article deals with a new method for modeling a pseudorandom number generator based on R-blocks. The gist of the method is the replacement of a multi digit XOR element by a stochastic adder in a parallel binary linear feedback shift register scheme

Intraformation Transformation of Heavy Oil by Mixed Fe(II, III) Oxides

© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Iron oxide (magnetite) particles are synthesized. Their effects on the transformation of high-molecular-mass components of Ashal'cha deposit heavy oil after simulating steam-heat action are studied. The contents of resinous asphaltenes are found to decrease if a catalyst is present in the oil. The viscosity decreases during hydrothermal catalytic action. Starting catalyst of mixed Fe(II, III) oxides and catalyst recovered from the oil were analyzed using x-ray structure analyses. Catalyst particle sizes were established using scanning electron microscopy