La producción científica sobre países latinoamericanos: una aproximación a su estudio desde la perspectiva bibliométrica y su relación con indicadores del contexto económico y social : PICT 2015-2744

Objetivos de la investigación - Contribuir al conocimiento de la configuración disciplinar y geográfica de la investigación sobre países de América Latina, producida tanto por países de la región como de otras regiones del mundo. - Contribuir al conocimiento de las prácticas de comunicación científica de la producción sobre países de la región latinoamericana a partir del estudio comparativo de la relación entre indicadores bibliométricos. - Contrastar los patrones encontrados en el estudio del caso argentino con los resultados obtenidos para el contexto latinoamericano. - Explorar relaciones entre Indicadores bibliométricos de la producción científica sobre países latinoamericanos e indicadores del contexto económico y social.Pósters presentadosDepartamento de Bibliotecologí

Informations diverses

Informations diverses. In: Comptes rendus des séances de l'Académie des Inscriptions et Belles-Lettres, 95ᵉ année, N. 1, 1951. p. 1

Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

Objectives: This study aimed to assess the real use of cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infective endocarditis (IE) in the Spanish National Endocarditis Database (GAMES) and to compare it with antistaphylococcal penicillin (ASP). Methods: Prospective cohort study with retrospective analysis of a cohort of MSSA IE treated with cloxacillin and/or cefazolin. Outcomes assessed were relapse; intra-hospital, overall, and endocarditis-related mortality; and adverse events. Risk of renal toxicity with each treatment was evaluated separately. Results: We included 631 IE episodes caused by MSSA treated with cloxacillin and/or cefazolin. Antibiotic treatment was cloxacillin, cefazolin, or both in 537 (85%), 57 (9%), and 37 (6%) episodes, respectively. Patients treated with cefazolin had significantly higher rates of comorbidities (median Charlson Index 7, P <0.01) and previous renal failure (57.9%, P <0.01). Patients treated with cloxacillin presented higher rates of septic shock (25%, P = 0.033) and new-onset or worsening renal failure (47.3%, P = 0.024) with significantly higher rates of in-hospital mortality (38.5%, P = 0.017). One-year IE-related mortality and rate of relapses were similar between treatment groups. None of the treatments were identified as risk or protective factors. Conclusion: Our results suggest that cefazolin is a valuable option for the treatment of MSSA IE, without differences in 1-year mortality or relapses compared with cloxacillin, and might be considered equally effective