PEDİATRİK HASTADA UNİLATERAL KONDİL KIRIĞI TEDAVİSİ: OLGU SUNUMU

Pediatrik hastada mandibula kondil kırıkları ciddi komplikasyonlara neden olabilen maksillofasiyal yaralanmalardır. Kondil kırıkları, mandibulanın en sık görülen kırıklarıdır. Tedavide açık ve kapalı yöntemler kullanılmaktadır. Özellikle pediatrik hastalarda kapalı yöntem, açık yönteme oranla daha çok tercih edilmektedir. Bu olgu sunumunun amacı, travma sonucu unilateral kondil kırığı olan hastanın kapalı yaklaşımla tedavi öncesi ve sonrası erken dönem klinik ve radyolojik bulgularının değerlendirilmesidir. Bu olgu sunumunda, masadan düşme sonucu kliniğimize başvuran ( 2, ♂ ) hastada unilateral kondil kırığının alt çeneye uygulanan oklüzyonu yükseltilmiş sert plak ve Barton bandajıyla tedavisi ele alındı. Haftalık yapılan kontroller sonucu 1.ay sonunda semptomlarda iyileşme ve kırık bölgesinde kallus oluşumu izlendi. Anahtar Kelimeler: Kondil kırığı, Mandibula, Pediatrik Hast

Treatment selection for de Quervain's tenosynovitis based on the Michigan’s Hand Questionnaire

Objective: De Quervain's disease is a stenosing tenosynovitis of the first dorsal compartment. Treatment options include conservative measures, injections, and surgery. The main purpose of this study is to eliminate uncertainty in the choice of treatment and to recommend the appropriate treatment to the patient based on Michigan hand questionnaire. Material and Methods: The age, sex, and treatment modality of the patients were recorded retrospectively. Patients' Michigan outcomes were assessed, and patients were divided into three groups: Patients who benefited from conservative treatments (Group 1), from injections (Group 2), and from surgery (Group 3). Statistical analysis of the data was performed. Results: The mean age of the 56 patients (54 women, 2 men) was 35.1±11.4 years. There was a difference between all groups in total hand function and pain scores (p 0.05). Conclusion: Various methods have been described for De Quervain's tenosynovitis’s treatment. Choosing the right therapeutic steps for the right patients is important. It is possible to select treatment options by assessing overall hand function and activities of daily living with the Michigan Hand Outcome Questionnair

Increased fat graft survival with mesenchymal stem cell recruiting effect of PRP: in vitro and in vivo study of application techniques

Aim: Adding platelet-rich plasm (PRP) or mesenchymal stem cells are the most accepted methods to increase fat graft’s permanence. However, there is no consensus on timing and whether the effect of stem cells or PRP is observed more in the recipient area or in the donor area. It is aimed to present the application method and localization of PRP to be combined with fat graft to increase the survival. Material and Methods: in vitro part: Fat grafts were kept in a medium containing PRP. Cell output from the fat graft to the Petri dishes was examined every day. The time to recruit the maximum number of stem cells to the medium was determined (day 10). in vivo part: Eight group of rats were received PRP in different concentrations either to recipient or donor areas of fat grafts. After ten days, fat grafts were transferred to the recipient area. Ninety days after the transfer, histopathological examination and immunohistochemical staining were performed. Results: The group which had received the full-dose PRP to the recipient area showed the highest cellular integrity and vascularity (p< 0.05). Vascularity was superior in the half-dose PRP group compared to the control group (p< 0.05); cellular integrity did not increase. Donor site groups did not show increase in cellular integrity. Conclusion: Although PRP starts to increase fat graft permanence by increasing vascularity, it acts by preserving the cellular integrity of the fat cells as the concentrations increase. The PRP injection to the recipient area 10 days before fat grafting may provide higher survival rates

DMEM ve HAMS F-12 sıvıları ile deri grefti yaşayabilirliğinin araştırılması

Klasik bir bilgi olarak deri greftleri izotonik serum içinde saklanmakta ve gerek otogreft, gerekse allogreft olarak kullanılabilmektedir. Saklanan bu greftlerin hücre yaşayabilirliğinin maksimum düzeyde tutulması klinik başarıyı artıracaktır. Ayrıca greft total keratinosit sayısını gündeme getirerek önemli bir parametre çalışıldı. Yaşlan 25-35 arasında değişen 26 hastaya ait pannükülektomi materyalleri steril şartlarda elde edilmiştir. 6 materyal mantar kontaminasyonu sebebiyle çalışmaya dahil edilmedi. 36 ml'ye bir (1) cm2 parça gelecek şekilde ve DMEM, Ham's F-12 solüsyonları içinde +4 °C'ye sabitlenmiş buzdolabına konularak 3 hafta saklanmıştır. DMEM ve Ham's F-12 solüsyonları dokular için besleyici özelliğe sahip sıvılardır. Bu sürenin sonunda materyaller PBS ile yıkanarak Tripsin EDTA ile muamele edildi. Epidermis dermişten ayrılarak manyetik karıştırıcı ile karıştırıldı. Bu süspansiyona tripan blue boyası ile viabilite testi yapıldı. DMEM ve Ham's F-12 ile elde edilen sonuçlar birbirine yakın ancak izotonik seruma göre oldukça yüksek bulunmuştur. Bu çalışma ile allogreft ve oto greft saklanmasında viabilitenin yeri olduğu ve başarılı olarak kullanılabileceği gösterilmiş oldu.Storage of the skin graft in serum physiologic is an routine application and these grafts may be used as an otograft or allograft. Better clinical results can be obtained by having maximum viability levels of the skin grafts. In this study graft keratinocytes quantity was emphasized that is an important parameter for the storage. Skin grafts were prepared from panniculectomi materials of 26 patients which were between 25-35 years old under steril conditions. Six (6) samples were excepted from the study because of fungal contamination. Each 1 cm2 skin grafts put into 36 ml. DMEM and Ham's F-12 mediums and preserved at +4 °C for 3 weeks. DMEM and Ham's F-12 fluids are nutrient mediums for the tissues. After 3 weeks storage period the skin grafts washed with PBS and transfered to Tripsin EDTA. Epidermis was separeted from dermis by mechanically and homogenized with magnetic mixer. Viability was measured after trypan blue application to the samples. The results of the viability which was obtained with DMEM and Ham's F-12 were almost the same but both were better than serum physiologic. This study indicated that viability assesment is an important part for the storage of the skin otograft and allograft and may be applicated successfully

Winer's Nodular Calcinosis Mimicking Squamous Cell Carcinoma On The Ear

Winer nodüler kalsinozis, doğumda ya da erken çocukluk çağı döneminde görülen asemptomatik, sert, sarı ya da beyaz renkte nodüler tarzda görülen, idiopatik kalsinozis kutisin bir alt formudur. Winer nodüler kalsinozis üzerinde ülserasyon gelişimi oldukça nadirdir. Ulaşılabilen Türkçe ya da İngilizce literatürde bugüne kadar Winer nodüler kalsinozis ile karişabilecek malign cilt lezyonundan bahseden benzer yazı ya da vakaya rastlanılmamıştır. Bu yazıda, sol kulak heliksinde beyaz renkte, üzeri ülsere, 3x2 mm boyutlarında nodüler lezyon şikayetiyle ailesi tarafından kliniğimize getirilen üç yaşında çocuk olgu sunuldu. Lezyonun ülsere olması, makroskobik görüntüsü ve güneş maruziyetinin en sık olduğu kulak heliksinde yerleşimi nedeniyle ön tanı olarak skuamöz hücreli karsinom düşünüldü.Winer's nodular calcinosis, presenting as an asymptomatic, firm, white, or yellow nodule at birth or during early childhood, is a form of idiopathic calcinosis cutis. Ulceration on Winer's nodular calcinosis is rarely seen. Till date, there is no report in the literature regarding the malignant skin lesion confused with Winer's nodular calcinosis. No similar case or article has been encountered in the Turkish or English literature regarding the malignant skin lesion that might be confused with Winer's nodular calcinosis. The case of a 3-year-old girl with a 3&times;2 mm, white, ulcerated, nodular lesion on the helix of the left ear is presented here. The lesion was thought to be a squamous cell carcinoma due to the ulceration and appearance, and it was located on the ear, which is frequently exposed to the sun

Rhabdomyosarcoma in an adult hand

Rhabdomyosarcoma (RMS) is a malign tumour which arises from cells committed to a skeletal muscle lineage. It constitutes 4%–8% of all childhood malignancies but is rare in adults. The rare pleomorphic subtype occurs almost exclusively in adults and most often involves the extremities. RMS of the hand or foot comprise a minority of extremity cases. An adult patient with rhabdomyosarcoma in the hand, which is very rare, is presented in this article. General characteristics of the tumour and the treatment strategies are discussed

Novel pthalocyanines bearing 4-ferrocenylphenoxy substituents and their electrochemistry

Biyiklioglu, Zekeriya/0000-0001-5138-214XWOS: 000327939000040The synthesis, spectroscopic and electrochemical properties of the tetra-(4-ferrocenylphenoxy) substituted metal-free, zinc(II) and cobalt(II) phthalocyanines reported for the first time. Metal-free, zinc(II) and cobalt(II) phthalocyanines were synthesized from 4-(ferrocenylphenoxy)phthalonitrile 3 which was obtained from 4-ferrocenylphenol 1 and 4-nitrophthalonitrile 2. The compounds have been characterized by IR, UV-Vis, H-1 NMR, C-13 NMR, MALDI-TOF mass spectral data. The electrochemical properties of the phthalocyanines were also investigated by cyclic and square wave voltammetry techniques. Cyclic and square wave voltammetric studies show that phthalocyanines have reversible/quasi-reversible redox processes, which are the main requirement for the technological usage of these compounds. (C) 2013 Elsevier B. V. All rights reserved.Research Fund of Karadeniz Technical University (Trabzon-Turkey)Karadeniz Teknik University [8660]This study was supported by the Research Fund of Karadeniz Technical University, project no: 8660, (Trabzon-Turkey)