16,304 research outputs found
Reserve Size And Fragmentation Alter Community Assembly, Diversity, And Dynamics
Researchers have disputed whether a single large habitat reserve will support more species than many small reserves. However, relatively little is known from a theoretical perspective about how reserve size affects competitive communities structured by spatial abiotic gradients. We investigate how reserve size affects theoretical communities whose assembly is governed by dispersal limitation, abiotic niche differentiation, and source-sink dynamics. Simulations were conducted with varying scales of dispersal across landscapes with variable environmental spatial autocorrelation. Landscapes were inhabited by simulated trees with seedling and adult stages. For a fixed total area in reserves, we found that small reserve systems increased the distance between environments dominated by different species, diminishing the effects of source-sink dynamics. As reserve size decreased, environmental limitations to community assembly became stronger, species richness decreased, and richness increased. When dispersal occurred across short distances, a large reserve strategy caused greater stochastic community variation, greater richness, and lower richness than in small reserve systems. We found that reserve size variation trades off between preserving different aspects of natural communities, including diversity versus diversity. Optimal reserve size will depend on the importance of source-sink dynamics and the value placed on different characteristics of natural communities. Anthropogenic changes to the size and separation of remnant habitats can have far-reaching effects on community structure and assembly.Integrative Biolog
DNA methylation and DNA methyltransferases
The prevailing views as to the form, function, and regulation of genomic methylation patterns have their origin many years in the past, at a time when the structure of the mammalian genome was only dimly perceived, when the number of protein-encoding mammalian genes was believed to be at least five times greater than the actual number, and when it was not understood that only ~10% of the genome is under selective pressure and likely to have biological function. We use more recent findings from genome biology and whole-genome methylation profiling to provide a reappraisal of the shape of genomic methylation patterns and the nature of the changes that they undergo during gametogenesis and early development. We observe that the sequences that undergo deep changes in methylation status during early development are largely sequences without regulatory function. We also discuss recent findings that begin to explain the remarkable fidelity of maintenance methylation. Rather than a general overview of DNA methylation in mammals (which has been the subject of many reviews), we present a new analysis of the distribution of methylated CpG dinucleotides across the multiple sequence compartments that make up the mammalian genome, and we offer an updated interpretation of the nature of the changes in methylation patterns that occur in germ cells and early embryos. We discuss the cues that might designate specific sequences for demethylation or de novo methylation during development, and we summarize recent findings on mechanisms that maintain methylation patterns in mammalian genomes. We also describe the several human disorders, each very different from the other, that are caused by mutations in DNA methyltransferase genes
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Cutaneous endometriosis.
Cutaneous endometriosis is a disorder that primarily affects women of reproductive age. The disorder is most commonly associated with cyclical pain during menses, but it can be difficult to diagnose in the absence of these symptoms and requires biopsy testing for a definitive diagnosis. We report on a case of a 41-year-old patient undergoing hormonal therapy for infertility who presented with a painful firm subcutaneous nodule in the umbilicus. She was ultimately diagnosed with cutaneous endometriosis and underwent surgical excision. In this report, we discuss the differential diagnosis and comment on treatment options, including surgical excision with wide margins or treatment with hormonal agents, such as danazol or leuprolide. Finally, we discuss whether patients with cutaneous endometriosis should receive an additional evaluation for pelvic endometriosis
Reduced density matrix hybrid approach: Application to electronic energy transfer
Electronic energy transfer in the condensed phase, such as that occurring in
photosynthetic complexes, frequently occurs in regimes where the energy scales
of the system and environment are similar. This situation provides a challenge
to theoretical investigation since most approaches are accurate only when a
certain energetic parameter is small compared to others in the problem. Here we
show that in these difficult regimes, the Ehrenfest approach provides a good
starting point for a dynamical description of the energy transfer process due
to its ability to accurately treat coupling to slow environmental modes. To
further improve on the accuracy of the Ehrenfest approach, we use our reduced
density matrix hybrid framework to treat the faster environmental modes quantum
mechanically, at the level of a perturbative master equation. This combined
approach is shown to provide an efficient and quantitative description of
electronic energy transfer in a model dimer and the Fenna-Matthews-Olson
complex and is used to investigate the effect of environmental preparation on
the resulting dynamics.Comment: 11 pages, 8 figure
Telling the tale of the first stars
HE 0107-5240 is a star in more than once sense of the word. Chemically, it is
the most primitive object yet discovered, and it is at the centre of debate
about the origins of the first elements in the Universe.Comment: 3 pages, 0 figures, published in Nature "News and Views," Apr. 24,
200
Report of the ultraviolet and visible sensors panel
In order to meet the science objectives of the Astrotech 21 mission set the Ultraviolet (UV) and Visible Sensors Panel made a number of recommendations. In the UV wavelength range of 0.01 to 0.3 micro-m the focus is on the need for large format high quantum efficiency, radiation hard 'solar-blind' detectors. Options recommended for support include Si and non-Si charge coupled devices (CCDs) as well as photocathodes with improved microchannel plate readouts. For the 0.3 to 0.9 micro-m range, it was felt that Si CCDs offer the best option for high quantum efficiencies at these wavelengths. In the 0.9 to 2.5 micro-m the panel recommended support for the investigation of monolithic arrays. Finally, the panel noted that the implementation of very large arrays will require new data transmission, data recording, and data handling technologies
Derivation of the Planck Spectrum for Relativistic Classical Scalar Radiation from Thermal Equilibrium in an Accelerating Frame
The Planck spectrum of thermal scalar radiation is derived suggestively
within classical physics by the use of an accelerating coordinate frame. The
derivation has an analogue in Boltzmann's derivation of the Maxwell velocity
distribution for thermal particle velocities by considering the thermal
equilibrium of noninteracting particles in a uniform gravitational field. For
the case of radiation, the gravitational field is provided by the acceleration
of a Rindler frame through Minkowski spacetime. Classical zero-point radiation
and relativistic physics enter in an essential way in the derivation which is
based upon the behavior of free radiation fields and the assumption that the
field correlation functions contain but a single correlation time in thermal
equilibrium. The work has connections with the thermal effects of acceleration
found in relativistic quantum field theory.Comment: 23 page
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