298 research outputs found
Age Differences in Attributions of Causality: Implications for Intellectual Assessment
The present investigation was designed to test the hypothesis that failure experienced by the individual in a testing situation is moderated by causal attributions and these attributions influence subsequent test measures. The effect of manipulating cause (lack of effort or Lack of ability) to response-independent failure and its relationship to scores on the Reasoning, Hidden Patterns, and Paper Folding Test, in younger an older person\u27s was investigated. The same measures were assessed in a group that experienced the same response-independent-failure but with no explanation offered as to the cause for the failure, a group that was not given any information concerning the outcome, and a control group that did not experience the response-independent-failure.
Analysis of results indicated that younger subjects obtained significantly higher scores than one subjects on all three subtests. A significant age by condition effect in results from the Paper Folding Test was also found. The failure-ability group showed lower scores than the failure-effort group for both age categories. The two non manipulated-attribution groups were lower than the failure-effort group for the elderly, and were higher than the failure-ability group for younger subjects. The results supported the hypothesis that elderly individuals may demonstrate lower cognitive scores in part, due to influences that are extraneous to cognitive assessment. Implications of the results for elderly cognitive assessment were discussed
MC ICP-MS δ 34SVCDT measurement of dissolved sulfate in environmental aqueous samples after matrix separation by means of an anion exchange membrane
Health Policy Development: Health Promotion and Illness Prevention Among Older Adults in Illinois
This paper offers recommendations for health promotion and illness prevention for older adults in Illinois and offers a structure for policy development. It is based on the premise that policy development should consider the experiences of older adults, family members, and health care providers delivering direct services. Personal experiences and expert analyses were examined in the context of strategies to promote health. This example of policy development is discussed in terms of its application to alternative methods of social and health change and identifies roles for the sociological practitioner
Interaction of Protein C Inhibitor with the Type II Transmembrane Serine Protease Enteropeptidase
The serine protease inhibitor protein C inhibitor (PCI) is expressed in many human tissues and exhibits broad protease reactivity. PCI binds glycosaminoglycans and certain phospholipids, which modulate its inhibitory activity. Enteropeptidase (EP) is a type II transmembrane serine protease mainly found on the brush border membrane of epithelial cells in the duodenum, where it activates trypsinogen to initiate the digestion of food proteins. Some active EP is also present in duodenal fluid and has been made responsible for causing pancreatitis in case of duodeno-pancreatic reflux. Together with its substrate trypsinogen, EP is furthermore present in the epidermis and in some cancer cells. In this report, we show that PCI inhibited EP with an apparent 2nd order rate constant of 4.48×104 M−1 s−1. Low molecular weight (LMWH) and unfractionated heparin (UFH) slightly reduced the inhibitory effect of PCI. The SI (stoichiometry of inhibition) value for the inhibition of EP by PCI was 10.8 in the absence and 17.9 in the presence of UFH (10 U/ml). By inhibiting trypsin, chymotrypsin, and additionally EP, PCI might play a role in the protection of the pancreas from autodigestion. Furthermore the interaction of PCI with EP may influence the regulation of epithelial differentiation
Opportunities and challenges for digital morphology
Advances in digital data acquisition, analysis, and storage have revolutionized the work in many biological disciplines such as genomics, molecular phylogenetics, and structural biology, but have not yet found satisfactory acceptance in morphology. Improvements in non-invasive imaging and three-dimensional visualization techniques, however, permit high-throughput analyses also of whole biological specimens, including museum material. These developments pave the way towards a digital era in morphology. Using sea urchins (Echinodermata: Echinoidea), we provide examples illustrating the power of these techniques. However, remote visualization, the creation of a specialized database, and the implementation of standardized, world-wide accepted data deposition practices prior to publication are essential to cope with the foreseeable exponential increase in digital morphological data
Does Place Matter When Understanding Loneliness and Social Isolation?
Physical distancing and restriction of movements as measures to prevent the spread of Covid-19 required people to change their work, home and social lives. Loneliness and social isolation have emerged as key public health issues during the pandemic. Traditionally when considering loneliness the focus is often on individual factors rather than within the context of structural and environmental dimensions. This paper will utilise data from the Coping with Loneliness, Isolation and Covid-19 global online survey which had over 20, 000 global responses from people aged 18+ in 2020. Analysis will use the lens of ‘place’ and the 5-item UCLA scale and 6-item Lubben social network scale to understand the social and demographic characteristics and structural and environmental factors associated with those experiencing loneliness and/or social isolation in rural and urban areas both before and during the pandemic. The paper will conclude with key messages from a public health perspective
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