Spontaneous Carotid Artery Dissection Presenting as Trigeminal Neuralgia in the Emergency Department

Introduction: Carotid artery dissection (CAD) is a critical diagnosis in the emergency department (ED). Trigeminal neuralgia, while not uncommon, may cause the patient significant discomfort but generally is not attributed to severe morbidity and mortality.Case Report: We present a case of spontaneous CAD presenting with the classic intermittent “lightning-like” jaw and head pain suggestive of trigeminal neuralgia that was ultimately diagnosed utilizing computed tomography angiogram after multiple visits to the ED.Discussion: Coincidentally the patient had been started on anticoagulation a few days prior and no additional intervention was required.Conclusion: This case report discusses current recommendations for diagnosis, treatment, and long-term prognosis of CAD

Konsumentenbefragungen zum Thema "Fair Trade" und "Bio" an Hochschulen in Nordrhein-Westfalen

Im Rahmen des 2013 gegründeten "Regionalen Forums für verantwortungsvolles Wirtschaften im Bereich Lebensmittel" wurde an der Hochschule Bonn-Rhein-Sieg und der Fachhochschule Köln eine Befragung zum Bekanntheitsgrad und zur Glaubwürdigkeit der Labels für "Fair Trade" und "Bio" durchgeführt. Zudem wurde die generelle Einstellung zu sowie die Kaufbereitschaft für fair gehandelte Produkte erfragt. Die Resultate konnten unter verschiedenen Aspekten (Stellung im Beruf und Einkommenshöhe, Alterskategorien, Geschlecht) differenziert analysiert werden. Im vorliegenden Beitrag werden ausgewählte Ergebnisse der Befragung vorgestellt

Hesitations and Aspirations of Farmers in Nature-Protected Areas

Pursuant to Sustainable Development Goal (SDG) 15 of the 2030 Agenda for Sustainable Development of the United Nations, one pivotal target is to halt biodiversity loss. This paper’s objective is to analyze why and how German farmers hesitate to implement more than the prescriptive measures with regard to cross compliance and direct payments under the European Common Agricultural Policy (CAP) and what their aspirations are for possible incentives to bring biodiversity into focus. By applying a mixed methods approach, we investigate the experience of individual farmers by means of a qualitative approach followed by a quantitative study. This analysis sheds light on how farmers perceive indirect influencing factors and how these factors play a non-negligible role in farmers´ commitment to biodiversity. Economy, policy and society are intertwined and need to be considered from a multi-faceted perspective. In addition, an in-depth analysis is conducted based on online focus group discussions to determine whether farmers accept financial support, focusing on both action- and success-oriented payments. Our results highlight the importance of paying attention to the heterogeneity of farmers, their locations and, consequently, farmers’ different views on indirect drivers influencing agricultural processes, showing the complexity of the problem. Although farmers’ expectations can be met with financial allocations, other aspects must also be taken into account

Influence of epidermal growth factor on long-term potentiation in the hippocampal slice.

Rat hippocampal slices were perfused with epidermal growth factor (EGF) at a concentration of 10−8 M. EGF is a well known mitogen which exhibits neurotrophic action on neurons of the CNS. During extra- and intracellular recordings in the pyramidal cell body layer of the CA1-region no influence of EGF on evoked potentials was seen if single-pulse or paired-pulse stimulation was used. Furthermore EGF has no influence on the resting membrane potential of the cells investigated. However after tetanic stimulation a significant increase in the magnitude of long-term potentiation was observed. Therefore it is concluded, that EGF might be involved in modulation of neuronal plasticity

Block of Shaker K+ channels by ĸ-conotoxin PVIIA is state dependent

Journal Articleĸ-conotoxin PVIIA is the first conotoxin known to interact with voltage-gated potassium channels by inhibiting Shaker-mediated currents. We studied the mechanism of inhibition and concluded that PVIIA blocks the ion pore with a 1:1 stoichiometry and that binding to open or closed channels is very different. Open-channel properties are revealed by relaxations of partial block during step depolarizations, whereas double-pulse protocols characterize the slower reequilibration of closed-channel binding

Insect-Friendly Path Margins and Diverse Stakeholder Perspectives - A Dialogue And Communication Strategy For The Agricultural Landscape On The Left Bank Of Rhine-Sieg District, Germany

In intensively used agricultural landscapes, path margins are one of the few refuges and nurseries for wildlife. They provide e. g. food sources and overwintering opportunities for many insects, serve as migration corridors for animals, protect soil from erosion, increase its water-holding capacity, and increase soil organic carbon, contributing thus directly to biodiversity conservation and climate change mitigation. Path margins are often municipally owned but used and managed by agriculture. For a path margin to be functional, certain conditions must be fulfilled, such as the width, the botanical composition, and how it is managed through the seasons. Therefore, it must be managed under specific requirements. A multifunctional path margin can be achieved only through the commitment of all stakeholders (e.g., farmers, municipalities, conservationists, and civil society)

Institutional Settings Surrounding Agriculture and Biodiversity: Challenges, Potentials and Obstacles of a Contract-based Nature Protection Scheme in the Rhine-Sieg District of Germany

Contract-based nature protection schemes are a voluntary mechanism, with a limited contract duration, that aim to raise the acceptance of biodiversity conservation practices in agriculture among farmers and other land users. The purpose of this paper is to analyse the institutional settings of contract-based nature protection based on the– “Institutions of Sustainability” (IoS) framework in the German Rhine-Sieg district, and to outline the way in which policy measures should be designed to encourage farmers to participate in contract-based nature protection programmes. This was achieved by answering research questions to identify the challenges, potentials and obstacles of a contract-based nature protection scheme in different “sub-arenas” as defined in the IoS framework. Qualitative research methods were used as the methodology. The analysis shows that main constraints for sufficient implementation of contract-based nature protection schemes are the limited consideration of the impact of climate change during the contract period, the limited consideration of regional conditions as regards the measures taken on the ground and an inflexible contract duration