769 research outputs found

    Novel D²T control for single-switch dual-output switching power converters

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    Author name used in this publication: C. K. TseAuthor name used in this publication: S. C. WongAuthor name used in this publication: K. C. TamRefereed conference paper2003-2004 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

    An improved wavelet approach for finding steady-state waveforms of power electronics circuits using discrete convolution

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    Author name used in this publication: Chi K. TseAuthor name used in this publication: Kam C. Tam2005-2006 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

    Spurious modulation on current-mode controlled dc/dc converters : an explanation for intermittent chaotic operation

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    Author name used in this publication: S. C. WongAuthor name used in this publication: C. K. TseAuthor name used in this publication: K. C. TamRefereed conference paper2003-2004 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

    Fast analytical approach to finding steady-state waveforms for power electronics circuits using orthogonal polynomial basis functions

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    Author name used in this publication: K. C. TamAuthor name used in this publication: S. C. WongAuthor name used in this publication: C. K. TseRefereed conference paper2005-2006 > Academic research: refereed > Refereed conference paperVersion of RecordPublishe

    Rheology And Dynamics Of Ph–Responsive Microgel Systems

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    The colloidal phenomenon of soft particles is an important field of research due to the growing interest in a variety of important systems found in biological science, such as vesicles, bi-layers, membranes, and living cells. Synthetic mono-dispersed colloida l suspensions in the nano to micron size range are increasingly becoming important model systems for the study of a variety of phenomena observed in soft condensed matter physics, such as glass transitions and crystal nucleation. In order to understand the behavior of these complex systems, we need to elucidate the relationship between the microscopic and macroscopic properties of these systems. In this presentation, we report on a study of a microgel system that offers us a platform to understand these relationships, and the physical forces that control their behavior. Please click Additional Files below to see the full abstract

    A sensor for parts inspection

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    This paper describes the development of a sensor which performs parts inspection by measuring the inertial properties of the part. The sensor comprises a platform supported on a column which is Used to a rigid base. The part under inspection is attached to the platform to form a single body. By measuring the static deflections of the column and the natural frequencies of vibration of the system, it is possible to determine the mass and the spatial location of the centre of mass of the part The information obtained is then used to distinguish defective parts from good ones.published_or_final_versio

    Metabolomics Analysis Reveals Specific Novel Tetrapeptide and Potential Anti-Inflammatory Metabolites in Pathogenic Aspergillus species

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    Infections related to Aspergillus species have emerged to become an important focus in infectious diseases, as a result of the increasing use of immunosuppressive agents and high fatality associated with invasive aspergillosis. However, laboratory diagnosis of Aspergillus infections remains difficult. In this study, by comparing the metabolomic profiles of the culture supernatants of 30 strains of six pathogenic Aspergillus species (A. fumigatus, A. flavus, A. niger, A. terreus, A. nomius and A. tamarii) and 31 strains of 10 non-Aspergillus fungi, eight compounds present in all strains of the six Aspergillus species but not in any strain of the non-Aspergillus fungi were observed. One of the eight compounds, Leu–Glu–Leu–Glu, is a novel tetrapeptide and represents the first linear tetrapeptide observed in Aspergillus species, which we propose to be named aspergitide. Two other closely related Aspergillus-specific compounds, hydroxy-(sulfooxy)benzoic acid and (sulfooxy)benzoic acid, may possess anti-inflammatory properties, as 2-(sulfooxy)benzoic acid possesses a structure similar to those of aspirin [2-(acetoxy)benzoic acid] and salicylic acid (2-hydroxybenzoic acid). Further studies to examine the potentials of these Aspergillus-specific compounds for laboratory diagnosis of aspergillosis are warranted and further experiments will reveal whether Leu–Glu–Leu–Glu, hydroxy-(sulfooxy)benzoic acid and (sulfooxy)benzoic acid are virulent factors of the pathogenic Aspergillus species. © 2015, MDPI AG. All rights Reserved.published_or_final_versio

    Coronary disease is not associated with robust alterations in inflammatory gene expression in human epicardial fat

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    Epicardial adipose tissue (EAT) is the visceral fat depot of the heart. Inflammation of EAT is thought to contribute to coronary artery disease (CAD). Therefore, we hypothesized that the EAT of patients with CAD would have increased inflammatory gene expression compared with controls without CAD. Cardiac surgery patients with (n = 13) or without CAD (n = 13) were consented, and samples of EAT and subcutaneous adipose tissue (SAT) were obtained. Transcriptomic analysis was performed using Affymetrix Human Gene 1.0 ST arrays. Differential expression was defined as a 1.5-fold change (ANOVA P \u3c 0.05). Six hundred ninety-three genes were differentially expressed between SAT and EAT in controls and 805 in cases. Expression of 326 genes was different between EAT of cases and controls; expression of 14 genes was increased in cases, while 312 were increased in controls. Quantitative reverse transcription PCR confirmed that there was no difference in expression of CCL2, CCR2, TNF-alpha, IL-6, IL-8, and PAI1 between groups. Immunohistochemistry showed more macrophages in EAT than SAT, but there was no difference in their number or activation state between groups. In contrast to prior studies, we did not find increased inflammatory gene expression in the EAT of patients with CAD. We conclude that the specific adipose tissue depot, rather than CAD status, is responsible for the majority of differential gene expression
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