Advantages and Limitations of Anticipating Laboratory Test Results from Regression- and Tree-Based Rules Derived from Electronic Health-Record Data

Laboratory testing is the single highest-volume medical activity, making it useful to ask how well one can anticipate whether a given test result will be high, low, or within the reference interval (“normal”). We analyzed 10 years of electronic health records—a total of 69.4 million blood tests—to see how well standard rule-mining techniques can anticipate test results based on patient age and gender, recent diagnoses, and recent laboratory test results. We evaluated rules according to their positive and negative predictive value (PPV and NPV) and area under the receiver-operator characteristic curve (ROC AUCs). Using a stringent cutoff of PPV and/or NPV≥0.95, standard techniques yield few rules for sendout tests but several for in-house tests, mostly for repeat laboratory tests that are part of the complete blood count and basic metabolic panel. Most rules were clinically and pathophysiologically plausible, and several seemed clinically useful for informing pre-test probability of a given result. But overall, rules were unlikely to be able to function as a general substitute for actually ordering a test. Improving laboratory utilization will likely require different input data and/or alternative methods

A Note on the Geometry of CHL Heterotic Strings

We present a few remarks on disconnected components of the moduli space of heterotic string compactifications on $T_2$. We show in particular how the eight dimensional CHL heterotic string can be understood in terms of topologically non-trivial $E_8\times E_8$ and \Spin(32)/Z_2 vector bundles over the torus, and that the respective moduli spaces coincide

Universal Features of Holographic Anomalies

We study the mechanism by which gravitational actions reproduce the trace anomalies of the holographically related conformal field theories. Two universal features emerge: a) the ratios of type B trace anomalies in any even dimension are independent of the gravitational action, being uniquely determined by the underlying algebraic structure b) the normalization of the type A and the overall normalization of the type B anomalies are given by action dependent expressions with the dimension dependence completely fixed.Comment: 17 pages, harvma

Avaliação técnico-econômica do controle de gramíneas em milho em área de várzea.

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Efeitos de extratos pirolenhosos utilizados como tratamento de sementes sobre doenças da fase Inicial e crescimento de plântulas de Soja.

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Ação de regulador do metabolismo de etileno sobre a produtividade de soja cultivada em terras baixas.

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Cultivo de soja em terras baixas em ano de El-niño.

bitstream/CPACT-2010/12314/1/soja-giovani.pdfPublicado em: site Portal do Agronegócio, em 4/11/09; e Jornal Diário da Manhã, em 5/11/09

Manejo da cultura da soja em terras baixas em safras com El-Niño.

bitstream/CPACT-2010/13003/1/folder-manejo-elnino.pdfResponsáveis técnicos: Giovani Theisen; Francisco de Jesus Vernetti Júnior; Júlio José Centeno da Silva (CPACT)