Multidisciplinary Researches in Cultural Heritage Studies: An Approach on Akkale Cistern in Erdemli, Mersin

Conservation, reinforcement and restoration of architectural heritage requires multidisciplinary approaches which should be organised in precise steps that are similar to those used in medical science. Architectural conservation decisions must rely on full understanding of the historical, material, structural, geological and environmental information related to the building and its setting. The aim of this paper is to discuss phases of a multidisciplinary approach applied to develop a conservation project for the ancient cistern building, located in Akkale archaeological site in Mersin (Turkey). Firstly, architectural description of the ancient cistern building in the light of current information revealed by archeological excavations is presented. Then, methods and technics conducted by each expert group are discussed explaining the main results obtained from each study. Finally, organization of multidisciplinary studies and results gained from each step are displayed through a flow chart diagram showing process of research and data from one phase to another to develop architectural conservation program

Results on light dark matter particles with a low-threshold CRESST-II detector

The CRESST-II experiment uses cryogenic detectors to search for nuclear recoil events induced by the elastic scattering of dark matter particles in CaWO$_4$ crystals. Given the low energy threshold of our detectors in combination with light target nuclei, low mass dark matter particles can be probed with high sensitivity. In this letter we present the results from data of a single detector module corresponding to 52 kg live days. A blind analysis is carried out. With an energy threshold for nuclear recoils of 307 eV we substantially enhance the sensitivity for light dark matter. Thereby, we extend the reach of direct dark matter experiments to the sub-region and demonstrate that the energy threshold is the key parameter in the search for low mass dark matter particles.Comment: 8 pages, 8 figure

Comparison of local rosmarinic acid and topical dexpanthenol applications on wound healing in a rat experimental wound model

Background: The aim of the study was to compare the effects of rosmarinic acid and dexpanthenol in a rat experimental wound model.Materials and methods: Twenty-four Wistar albino rats weighing 200–250 g were randomly divided into three groups. After 2-cm full-thickness skin defects were created, the wounds were washed with sterile 0.9% NaCl solution. After washing, the control group was left untreated, the second group received 5% dexpanthenol cream, and the third group received 10% rosmarinic acid cream. Before excision, the skin was evaluated macroscopically by measuring the reduction in wound size; after excision, histological examination (epithelisation, inflammation, fibrosis, granulation) was performed.Results: Macroscopic comparison of the wound sizes showed that group 3 showed a statistically significant difference in wound size reduction compared to the other two groups. Histopathological examination showed that there was no statistically significant difference between the groups. We found that the rosmarinic acid group had greater wound size reduction than the other two groups. However, epithelialisation was detected in fewer cases.Conclusions: We believe that rosmarinic acid can be used as a topical cream for wound healing, as it leads to significant reduction in wound size, resulting in fewer scars

FARKLI TUTKALLARIN KAYIN ve SARIÇAM AĞAÇLARINDAKİ YAPIŞMA DİRENÇLERİNİN BELİRLENMESİ

Bu çalışmada, poliüretan esaslı Pu-Mon ve Pu-Ma, polivinilasetat esaslı PVAc-MA22, PVAc-MA35 ve PVAc-MA50 ile yapıştırılmış Doğu kayını (Fagus orientalis L.) ve sarıçam (Pinus Sylvestris L.) odunlarının yapışma direnci, TS EN 205 esaslarına göre belirlenmiştir. Deney sonuçlarına göre, en yüksek yapışma direnci Pu-Ma (16.01 N/mm2) ve PVAc-MA35 (15.12 N/mm2) ile yapıştırılmış kayın numunelerinde, en düşük yapışma direnci ise Pu-Mon (7.98 N/mm2) ve PVAc-MA35 (7.67 N/mm2) ile yapıştırılmış sarıçam numunelerinde tespit edilmiştir. 

Multidrug resistant Acinetobacter baumannii: a descriptive study in a city hospital

<p>Abstract</p> <p>Background</p> <p>Multidrug resistant <it>Acinetobacter baumannii</it>, (MRAB) is an important cause of hospital acquired infection. The purpose of this study is to determine the risk factors for MRAB in a city hospital patient population.</p> <p>Methods</p> <p>This study is a retrospective review of a city hospital epidemiology data base and includes 247 isolates of Acinetobacter baumannii (AB) from 164 patients. Multidrug resistant <it>Acinetobacter baumannii </it>was defined as resistance to more than three classes of antibiotics. Using the non-MRAB isolates as the control group, the risk factors for the acquisition of MRAB were determined.</p> <p>Results</p> <p>Of the 247 AB isolates 72% (177) were multidrug resistant. Fifty-eight percent (143/247) of isolates were highly resistant (resistant to imipenem, amikacin, and ampicillin-sulbactam). Of the 37 patients who died with Acinetobacter colonization/infection, 32 (86%) patients had the organism recovered from the respiratory tract. The factors which were found to be significantly associated (p ≤ 0.05) with multidrug resistance include the recovery of AB from multiple sites, mechanical ventilation, previous antibiotic exposure, and the presence of neurologic impairment. Multidrug resistant Acinetobacter was associated with significant mortality when compared with sensitive strains (p ≤ 0.01). When surgical patients (N = 75) were considered separately, mechanical ventilation and multiple isolates remained the factors significantly associated with the development of multidrug resistant Acinetobacter. Among surgical patients 46/75 (61%) grew a multidrug resistant strain of AB and 37/75 (40%) were resistant to all commonly used antibiotics including aminoglycosides, cephalosporins, carbepenems, extended spectrum penicillins, and quinolones. Thirty-five percent of the surgical patients had AB cultured from multiple sites and 57% of the Acinetobacter isolates were associated with a co-infecting organism, usually a Staphylococcus or Pseudomonas. As in medical patients, the isolation of Acinetobacter from multiple sites and the need for mechanical ventilation were significantly associated with the development of MRAB.</p> <p>Conclusions</p> <p>The factors significantly associated with MRAB in both the general patient population and surgical patients were mechanical ventilation and the recovery of Acinetobacter from multiple anatomic sites. Previous antibiotic use and neurologic impairment were significant factors in medical patients. Colonization or infection with MRAB is associated with increased mortality.</p

TES-Based Light Detectors for the CRESST Direct Dark Matter Search

The CRESST experiment uses cryogenic detectors based on transition-edge sensors to search for dark matter interactions. Each detector module consists of a scintillating CaWO₄ crystal and a silicon-on-sapphire (SOS) light detector which operate in coincidence (phonon-light technique). The 40-mm-diameter SOS disks (2 g mass) used in the data taking campaign of CRESST-II Phase 2 (2014–2016) reached absolute baseline resolutions of σ = 4–7 eV. This is the best performance reported for cryogenic light detectors of this size. Newly developed silicon beaker light detectors (4 cm height, 4 cm diameter, 6 g mass), which cover a large fraction of the target crystal surface, have achieved a baseline resolution of σ = 5.8 eV. First results of further improved light detectors developed for the ongoing low-threshold CRESST-III experiment are presented. Keywords: Transition-edge sensor; Cryogenic light detector; Direct dark matter searc