200 research outputs found
Effect of soil properties on pyroxasulfone bioactivity and field application rates
Non-Peer ReviewedThe relationship between pyroxasulfone bioactivity and soil properties has not been investigated in a wide range of soils typical of western Canada. In this study, 47 soils from Saskatchewan, Manitoba and Alberta, with varying organic matter content (1.5 to 22.1%), pH (5.0 to 7.9), and clay content (6.8 to 59.4%) were used to evaluate the effect of soil properties on pyroxasulfone bioactivity and its relevance to field application rates. Bioactivity was assessed by measuring the reduction of sugar beet shoot length after 7 days in response to 0, 92, 184, and 368 ÎĽg ai kg-1 pyroxasulfone concentration in soil. Multiple regression analysis showed that pyroxasulfone bioactivity was related to soil organic matter content, pH and clay content. Grouping the soils according to these properties allowed for a summarization of pyroxasulfone field application rates required to achieve bioactivity based on the magnitude of sugar beet shoot length inhibition (%). The estimated field application rates ranged from less than 120 to 480 g ai ha-1
Strong asymptotics for Cauchy biorthogonal polynomials with application to the Cauchy two--matrix model
We apply the nonlinear steepest descent method to a class of 3x3
Riemann-Hilbert problems introduced in connection with the Cauchy two-matrix
random model. The general case of two equilibrium measures supported on an
arbitrary number of intervals is considered. In this case, we solve the
Riemann-Hilbert problem for the outer parametrix in terms of sections of a
spinorial line bundle on a three-sheeted Riemann surface of arbitrary genus and
establish strong asymptotic results for the Cauchy biorthogonal polynomials.Comment: 31 pages, 12 figures. V2; typos corrected, added reference
Multipeakons and a theorem of Stieltjes
A closed form of the multi-peakon solutions of the Camassa-Holm equation is
found using a theorem of Stieltjes on continued fractions. An explicit formula
is obtained for the scattering shifts.Comment: 6 page
Assessment of Wild Mustard (Sinapis arvensis L.) Resistance to ALS-inhibiting Herbicides
There is an urgent need for rapid, accurate, and economical screening tests that can determine if weeds surviving a herbicide application are resistant. This chapter describes development and application of a simple root length bioassay technique for detection of wild mustard (Sinapis arvensis L.) resistance to ALS-inhibiting herbicides. This bioassay was performed in 2-oz WhirlPak® bags filled with 50 g of soil wetted to 100% moisture content at field capacity. Wild mustard seeds were pre-germinated in darkness in Petri dishes lined with moist filter paper for 2 days. Six seeds with well-developed radicles were planted in the non-treated soil and in soil with added herbicide, and plants were grown in a laboratory under fluorescent lights. After 4 days of growth, WhirlPak® bags were cut open, soil was washed away, intact plants were removed, and root length was measured with a ruler. The concentration of each herbicide in soil at which a significant root inhibition of susceptible biotype, but no root inhibition of a resistant biotype occurred was selected. Susceptibility/resistance of wild mustard populations was estimated by calculating the percentage of uninhibited roots of plants grown in the herbicide-treated soil as compared to the plants grown in the non-treated soil
Using electronic health records to support clinical trials: a report on stakeholder engagement for EHR4CR
Background. The conduct of clinical trials is increasingly challenging due to greater complexity and governance requirements as well as difficulties with recruitment and retention. Electronic Health Records for Clinical Research (EHR4CR) aims at improving the conduct of trials by using existing routinely collected data, but little is known about stakeholder views on data availability, information governance, and acceptable working practices. Methods. Senior figures in healthcare organisations across Europe were provided with a description of the project and structured interviews were subsequently conducted to elicit their views. Results. 37 structured interviewees in Germany, UK, Switzerland, and France indicated strong support for the proposed EHR4CR platform. All interviewees reported that using the platform for assessing feasibility would enhance the conduct of clinical trials and the majority also felt it would reduce workloads. Interviewees felt the platform could enhance trial recruitment and adverse event reporting but also felt it could raise either ethical or information governance concerns in their country. Conclusions. There was clear support for EHR4CR and a belief that it could reduce workloads and improve the conduct and quality of trials. However data security, privacy, and information governance issues would need to be carefully managed in the development of the platform
Moment determinants as isomonodromic tau functions
We consider a wide class of determinants whose entries are moments of the
so-called semiclassical functionals and we show that they are tau functions for
an appropriate isomonodromic family which depends on the parameters of the
symbols for the functionals. This shows that the vanishing of the tau-function
for those systems is the obstruction to the solvability of a Riemann-Hilbert
problem associated to certain classes of (multiple) orthogonal polynomials. The
determinants include Haenkel, Toeplitz and shifted-Toeplitz determinants as
well as determinants of bimoment functionals and the determinants arising in
the study of multiple orthogonality. Some of these determinants appear also as
partition functions of random matrix models, including an instance of a
two-matrix model.Comment: 24 page
Competition of IL-1 and IL-1ra determines lymphocyte response to delayed stimulation with PHA.
BACKGROUND: Human peripheral blood mononuclear cells (PBMC) left in microcultures for 24h without mitogen do not respond to subsequent stimulation with PHA. They regain reactivity if the native culture medium is absorbed with other party lymphocytes or partially replaced with the medium from a PHA-stimulated culture. The observations suggest that, during the incubation, some inhibitory agent had accumulated in the culture medium. AIM: The study was performed to determine the nature of the observed phenomenon in respect of the possible role of monocytes and their products IL-1 and IL-1 receptor antagonist (IL-1ra), and to test for immunodiagnostic purposes the significance of quantifying the lymphocyte response to delayed stimulation with PHA in patients suffering from inflammatory prosesses. METHODS: Lymphocyte response to delayed stimulation with PHA, calculated as the lymphocyte-monokine interaction (LM) index, was determined in the microcultures of PBMC isolated from the blood of healthy donors or of patients with acute tonsilitis. The values of LM indices were compared with the ratios of IL-1ra/IL-1beta concentration estimated by enzyme-linked immunosorbent assay method in the culture supernatants. The influences of exogenous IL-1beta, IL-1ra, anti-IL1ra antibodies and antibiotic cefaclor on the monokine concentrations and on the values of LM index were tested. RESULTS AND CONCLUSIONS: The results show that the level of lymphocyte response to delayed stimulation with PHA (LM index) is inversely proportional to the ratio of IL-1ra/IL-1beta concentration in the culture. The low LM values at high IL-1ra/IL-1beta ratios in PBMC cultures from healthy donors, reversed proportions found in patients' PBMC (acute tonsilitis), and the cefaclor-induced reduction of LM value with correlated increase of the IL-1ra/IL-1beta ratio suggest that the LM assay may prove to be useful for immunodiagnostic purposes
Characterization of polar organosulfates in secondary organic aerosol from the unsaturated aldehydes 2-E-pentenal, 2-E-hexenal, and 3-Z-hexenal
We show in the present study that the unsaturated aldehydes 2-E-pentenal, 2-E-hexenal, and 3-Z-hexenal are biogenic volatile organic compound (BVOC) precursors for polar organosulfates with molecular weights (MWs) 230 and 214, which are also present in ambient fine aerosol from a forested site, i.e., K-puszta, Hungary. These results complement those obtained in a previous study showing that the green leaf aldehyde 3-Z-hexenal serves as a precursor for MW 226 organosulfates. Thus, in addition to isoprene, the green leaf volatiles (GLVs) 2-E-hexenal and 3-Z-hexenal, emitted due to plant stress (mechanical wounding or insect attack), and 2-E-pentenal, a photolysis product of 3-Z-hexenal, should be taken into account for secondary organic aerosol and organosulfate formation. Polar organosulfates are of climatic relevance because of their hydrophilic properties and cloud effects. Extensive use was made of organic mass spectrometry (MS) and detailed interpretation of MS data (i.e., ion trap MS and accurate mass measurements) to elucidate the chemical structures of the MW 230, 214 and 170 organosulfates formed from 2-E-pentenal and indirectly from 2-E-hexenal and 3-Z-hexenal. In addition, quantum chemical calculations were performed to explain the different mass spectral behavior of 2,3-dihydroxypentanoic acid sulfate derivatives, where only the isomer with the sulfate group at C-3 results in the loss of SO3. The MW 214 organosulfates formed from 2-E-pentenal are explained by epoxidation of the double bond in the gas phase and sulfation of the epoxy group with sulfuric acid in the particle phase through the same pathway as that proposed for 3-sulfooxy-2-hydroxy-2-methylpropanoic acid from the isoprene-related alpha,beta-unsaturated aldehyde methacrolein in previous work (Lin et al., 2013). The MW 230 organosulfates formed from 2-E-pentenal are tentatively explained by a novel pathway, which bears features of the latter pathway but introduces an additional hydroxyl group at the C-4 position. Evidence is also presented that the MW 214 positional isomer, 2-sulfooxy-3-hydroxypentanoic acid, is unstable and decarboxylates, giving rise to 1-sulfooxy-2-hydroxybutane, a MW 170 organosulfate. Furthermore, evidence is obtained that lactic acid sulfate is generated from 2-E-pentenal. This chemistry could be important on a regional and local scale where GLV emissions such as from grasses and cereal crops are substantial
Inverse problems associated with integrable equations of Camassa-Holm type; explicit formulas on the real axis, I
The inverse problem which arises in the Camassa--Holm equation is revisited
for the class of discrete densities. The method of solution relies on the use
of orthogonal polynomials. The explicit formulas are obtained directly from the
analysis on the real axis without any additional transformation to a "string"
type boundary value problem known from prior works
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