A new way to determine the neutrino mass hierarchy at reactors

The determination of the neutrino mass ordering is currently pursued by several experiments and proposals. A very challenging one is its evaluation from reactor experiments based on the tiny interference effect between the $\Delta m^2_{31}$ and $\Delta m^2_{32}$ oscillations. Current analyses require several years of data taking and an extreme energy resolution to achieve anyhow less than 5 $\sigma$. Referring to the JUNO experimental conditions we developed a completely new technique that would provide a robust 5 $\sigma$ measurement in less than six years of running. The two orderings could be discriminated at the price of allowing for two different values of $\Delta m^2_{31}$. This degeneracy on $\Delta m^2_{31}$ (around $12\times 10^{-5}$ eV$^2$) can however be measured at an unprecedented accuracy of much less than 1\%, i.e. $10^{-5}$ eV$^2$, within the same analysis. Analogies with the usual $\chi^2$ analysis, where the $\Delta m^2_{31}$ degeneracy is much more important, are discussed. Evaluation and inclusion of systematic errors and backgrounds have been performed, the most relevant among them being the addition of the two remote reactor plants 250 km away. Baselines of each contributing reactor core and its spatial resolution have been taken into account. Possible results after two years of running and the foreseen initially-reduced available reactor power have been studied, too. These results confirm the very positive perspectives for JUNO to determine the mass ordering in a vacuum-oscillation dominated region.Comment: 37 pages, 22 figures, in this version added one more appendix about Chi^2, formal foundation of F as optimal estimator, submitted to JHE

I nidi domiciliari nelle Marche: una nuova realt\ue0 educativa

Il contributo ha l'obiettivo di definire uno dei servizi integrativi innovativi per la prima infanzia, ossia quello dei nidi domiciliari. Tale realt\ue0 educativa, infatti, si sta diffondendo anche in Italia, grazie pure alla promozione e agli investimenti di molte regioni. In particolare, \ue8 stata esaminata la legislazione di riferimento della Regione Marche, unitamente al profilo professionale dell'operatrice di nido domiciliare e alla sua formazione. Infine, attraverso la somministrazione di un questionario, rivolto sia alle educatrici di nido domiciliare, sia ai genitori dei bambini frequentanti il servizio, si \ue8 riusciti a definire, per le prime, un quadro su chi opera in questo campo, sulla motivazione a svolgere tale professione, sulle difficolt\ue0 incontrate e sulle scelte operative, mentre ai genitori \ue8 stato chiesto come e perch\ue9 si siano orientati verso una scelta cos\uec particolare, permettendo anche di confermare la loro piena soddisfazione

Spontaneous sealing of a type Ia endoleak after ovation stent graft implantation in a patient with on-label aortic neck anatomy

We report a case of an early type Ia endoleak after endovascular aneurysm repair (EVAR) of an abdominal aortic aneurysm by Ovation Stent Graft implantation and spontaneously resolved without further reintervention. The patient presents a conical aortic neck, but EVAR was performed within the instruction for use proposed by manufactory. At completion angiography, a low-flow type Ia endoleak was present and left untreated. Computed tomographic angiography performed on the third postoperative day showed infolding of the 2 sealing rings. The patient was dismissed without further treatment. At 3-month follow-up, the leak appeared spontaneously sealed with partial expansion of the 2 rings.We report a case of an early type Ia endoleak after endovascular aneurysm repair (EVAR) of an abdominal aortic aneurysm by Ovation Stent Graft implantation and spontaneously resolved without further reintervention. The patient presents a conical aortic neck, but EVAR was performed within the instruction for use proposed by manufactory. At completion angiography, a low-flow type Ia endoleak was present and left untreated. Computed tomographic angiography performed on the third postoperative day showed infolding of the 2 sealing rings. The patient was dismissed without further treatment. At 3-month follow-up, the leak appeared spontaneously sealed with partial expansion of the 2 rings

NI-DPU ASW v1.3.8 Test Plan and Test Report

The objective of this document is to provide the test plan carried out on v1.3.8 of the DPU ASW and to report the test results. All tests were done at system level. This document is focused on the ASW test phase carried out on DPU AVM at TAS premises in Turin after its qualification to validate the applicative before installing it on DPU FM unit

Zero Bias Configuration - validation test using the NI-PLM setup

The validation of the ZBC procedure applied to the NISP flight hardware is describe

DPU-ASW Management of the DCU ERROR REG content with possible off-line recovery actions

A new strategy is defined for the management of the errors in the DCU science interface dedicated to the scientific data acquisitio

N-Heterocyclic Carbene (NHC) Silver Complexes as Versatile Chemotherapeutic Agents Targeting Human Topoisomerases and Actin

In recent years, the number of people suffering from cancer has risen rapidly and the World Health Organization and U.S. and European governments have identified this pathology as a priority issue. It is known that most bioactive anticancer molecules do not target a single protein but exert pleiotropic effects, simultaneously affecting multiple pathways. In our study, we designed and synthesized a new series of silver N-heterocyclic carbene (NHC) complexes [(NHC)(2)Ag](+)[AgX2](-) (X=iodide or acetate). The new complexes were active against two human breast cancer cell lines, MCF-7 and MDA-MB-231. These compounds showed multiple target actions as anticancer, by inhibiting in vitro the activity of the human topoisomerases I and II and interfering with the cytoskeleton dynamic, as also confirmed by in silico studies. Moreover, the antimicrobial activity of these silver complexes was studied against Gram-positive/negative bacteria. These dual properties provide a two-tiered approach, making these compounds of interest to be further deepened for the development of new chemotherapeutic agents

Nuclear emulsion techniques for muography

Nuclear emulsions are currently being used in the field of muography, more specifically muon radiography of volcanic edifices and fault regions. The peculiar features of such detector for cosmic muons demand appropriate data processing and analysis techniques. The paper shows the current development status of readout devices and analysis techniques developed by some research groups that established a collaborative network in Italy and Japan. An overview is given of nuclear emulsion-based detectors, from the detection principles to detector operation and set-up techniques, in connection with the expectations in terms of geophysics information. Two systems for readout are presented, one developed in the first decade of the 21st century and one that is entering duty now. The evolution in terms of data quality and speed is discussed. Finally, the most relevant data processing steps that allow working out muon absorption maps from nuclear emulsion data are described