29 research outputs found
Moral-psychological attitudes student
This article analyzes the moral attitudes of students in vocational educationСтатья посвящена анализу морально-психологических установок студентов в учреждениях профессионального образовани
Communicative competence
This article explains the concept of communicative competence, discusses the process and stages of its development, and performance criteria. Particular attention is paid to the use of information and communication technologies in the educational process as an important factor in successful communication between student and teacherВ данной статье раскрывается понятие коммуникативной компетентности, рассматривается процесс и этапы её развития, критерии эффективности. Особое внимание уделено использованию информационно-коммуникационных технологий в образовательном процессе как важного фактора успешности коммуникации между студентом и преподавателе
Principles and norms of morality manager
In the article are considered some of the norms and principles of ethical behavior of the manager with which you can achieve success in a career. Under the norms and principles mean what behaviour during ethically acceptable and what is not. These rules are related first of all, how and on what basis are given instruction in the governance process, what is the service discipline, defines business communicationВ статье рассмотрены некоторые нормы и принципы нравственного поведения менеджера, с которыми можно достичь успеха в карьере. Под нормами и принципами имеется в виду то, какое поведение на службе этически приемлемо, а какое - нет. Эти нормы касаются прежде всего, как и на основе чего отдаются распоряжения в процессе управления, в чем выражается служебная дисциплина, определяющая деловое общени
The main features of the service sector and ways of its improvement on the example of the city Magnitogorsk
В данной статье рассмотрены основные проблемы и трудности, связанные на сегодняшний день со сферой услуг и торговли.This article describes the main problems and difficulties to date with the scope of services and trade
Particularly of education service
В статье рассмотрены особенности образовательного сервиса, которые учитываются в практике обучения студентов вуза.In the article the peculiarities of education services, which a taken into account in the learning process of students
Two-tape finite automata with quantum and classical states
{\it Two-way finite automata with quantum and classical states} (2QCFA) were
introduced by Ambainis and Watrous, and {\it two-way two-tape deterministic
finite automata} (2TFA) were introduced by Rabin and Scott. In this paper we
study 2TFA and propose a new computing model called {\it two-way two-tape
finite automata with quantum and classical states} (2TQCFA). First, we give
efficient 2TFA algorithms for recognizing languages which can be recognized by
2QCFA. Second, we give efficient 2TQCFA algorithms to recognize several
languages whose status vis-a-vis 2QCFA have been posed as open questions, such
as . Third, we show that
can be recognized by {\it -tape
deterministic finite automata} (TFA). Finally, we introduce {\it
-tape automata with quantum and classical states} (TQCFA) and prove that
can be recognized by TQCFA.Comment: 25 page
Social visual attentional engagement and memory in Phelan-McDermid syndrome and autism spectrum disorder: a pilot eye tracking study
Background
The current study used eye tracking to investigate attention and recognition memory in Phelan-McDermid syndrome (PMS), a rare genetic disorder characterized by intellectual disability, motor delays, and a high likelihood of comorbid autism spectrum disorder (ASD). Social deficits represent a core feature of ASD, including decreased propensity to orient to or show preference for social stimuli.
Methods
We used a visual paired-comparison task with both social and non-social images, assessing looking behavior to a novel image versus a previously viewed familiar image to characterize social attention and recognition memory in PMS (n = 22), idiopathic ASD (iASD, n = 38), and typically developing (TD) controls (n = 26). The idiopathic ASD cohort was divided into subgroups with intellectual disabilities (ID; developmental quotient 70) and the PMS group into those with and without a co-morbid ASD diagnosis.
Results
On measures of attention, the PMS group with a comorbid ASD diagnosis spent less time viewing the social images compared to non-social images; the rate of looking back and forth between images was lowest in the iASD with ID group. Furthermore, while all groups demonstrated intact recognition memory when novel non-social stimuli were initially presented (pre-switch), participants with PMS showed no preference during the post-switch memory presentation. In iASD, the group without ID, but not the group with ID, showed a novelty preference for social stimuli. Across indices, individuals with PMS and ASD performed more similarly to PMS without ASD and less similarly to the iASD group.
Conclusion
These findings demonstrate further evidence of differences in attention and memory for social stimuli in ASD and provide contrasts between iASD and PMS
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Rapid and objective assessment of neural function in autism spectrum disorder using transient visual evoked potentials
OBJECTIVE:
There is a critical need to identify biomarkers and objective outcome measures that can be used to understand underlying neural mechanisms in autism spectrum disorder (ASD). Visual evoked potentials (VEPs) offer a noninvasive technique to evaluate the functional integrity of neural mechanisms, specifically visual pathways, while probing for disease pathophysiology.
METHODS:
Transient VEPs (tVEPs) were obtained from 96 unmedicated children, including 37 children with ASD, 36 typically developing (TD) children, and 23 unaffected siblings (SIBS). A conventional contrast-reversing checkerboard condition was compared to a novel short-duration condition, which was developed to enable objective data collection from severely affected populations who are often excluded from electroencephalographic (EEG) studies.
RESULTS:
Children with ASD showed significantly smaller amplitudes compared to TD children at two of the earliest critical VEP components, P60-N75 and N75-P100. SIBS showed intermediate responses relative to ASD and TD groups. There were no group differences in response latency. Frequency band analyses indicated significantly weaker responses for the ASD group in bands encompassing gamma-wave activity. Ninety-two percent of children with ASD were able to complete the short-duration condition compared to 68% for the standard condition.
CONCLUSIONS:
The current study establishes the utility of a short-duration tVEP test for use in children at varying levels of functioning and describes neural abnormalities in children with idiopathic ASD. Implications for excitatory/inhibitory balance as well as the potential application of VEP for use in clinical trials are discussed
Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder
We systematically analyzed postzygotic mutations (PZMs) in whole-exome sequences from the largest collection of trios (5,947) with autism spectrum disorder (ASD) available, including 282 unpublished trios, and performed resequencing using multiple independent technologies. We identified 7.5% of de novo mutations as PZMs, 83.3% of which were not described in previous studies. Damaging, nonsynonymous PZMs within critical exons of prenatally expressed genes were more common in ASD probands than controls (P < 1 Ã 10-6), and genes carrying these PZMs were enriched for expression in the amygdala (P = 5.4 Ã 10-3). Two genes (KLF16 and MSANTD2) were significantly enriched for PZMs genome-wide, and other PZMs involved genes (SCN2A, HNRNPU and SMARCA4) whose mutation is known to cause ASD or other neurodevelopmental disorders. PZMs constitute a significant proportion of de novo mutations and contribute importantly to ASD risk