117 research outputs found

    Contextual constraints on noun distributions to some English verbs by children and adults

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    The cloze procedure was used to obtain noun distributions for subjects and objects of 36 common English transitive verbs in active and passive sentence frames. For third and sixth grade and college students, the subject nouns selected were more human and animate than object nouns, linguistic selectional rules correctly predicted relative animacy, humanness, and informational uncertainty for each function, and subject-object interacted on all these properties with active-passive. Distributions obtained from adults contained more inanimate nouns (where permissible), more information uncertainty, and had smaller intersections with each other than complementary distributions obtained from children.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/34162/1/0000450.pd

    Political parties and democratic consolidation in post-communist societies

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    Political parties have a central role to play in democratic consolidation, yet we know comparatively little about how effectively they represent social cleavages in newly emerging democracies. Using the Lipset–Rokkan framework, this article examines the role of parties in articulating social cleavages in 14 established and 6 emerging democracies using the Comparative Study of Electoral Systems datasets. The results show that the social cleavages in the emerging democracies are similar to those of the established democracies, with religion and class predominating. Parties appear to be less effective in representing social cleavages in the emerging than in the established democracies

    Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism.

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    BACKGROUND: The use of levothyroxine to treat subclinical hypothyroidism is controversial. We aimed to determine whether levothyroxine provided clinical benefits in older persons with this condition. METHODS: We conducted a double-blind, randomized, placebo-controlled, parallel-group trial involving 737 adults who were at least 65 years of age and who had persisting subclinical hypothyroidism (thyrotropin level, 4.60 to 19.99 mIU per liter; free thyroxine level within the reference range). A total of 368 patients were assigned to receive levothyroxine (at a starting dose of 50 μg daily, or 25 μg if the body weight was <50 kg or the patient had coronary heart disease), with dose adjustment according to the thyrotropin level; 369 patients were assigned to receive placebo with mock dose adjustment. The two primary outcomes were the change in the Hypothyroid Symptoms score and Tiredness score on a thyroid-related quality-of-life questionnaire at 1 year (range of each scale is 0 to 100, with higher scores indicating more symptoms or tiredness, respectively; minimum clinically important difference, 9 points). RESULTS: The mean age of the patients was 74.4 years, and 396 patients (53.7%) were women. The mean (±SD) thyrotropin level was 6.40±2.01 mIU per liter at baseline; at 1 year, this level had decreased to 5.48 mIU per liter in the placebo group, as compared with 3.63 mIU per liter in the levothyroxine group (P<0.001), at a median dose of 50 μg. We found no differences in the mean change at 1 year in the Hypothyroid Symptoms score (0.2±15.3 in the placebo group and 0.2±14.4 in the levothyroxine group; between-group difference, 0.0; 95% confidence interval [CI], -2.0 to 2.1) or the Tiredness score (3.2±17.7 and 3.8±18.4, respectively; between-group difference, 0.4; 95% CI, -2.1 to 2.9). No beneficial effects of levothyroxine were seen on secondary-outcome measures. There was no significant excess of serious adverse events prespecified as being of special interest. CONCLUSIONS: Levothyroxine provided no apparent benefits in older persons with subclinical hypothyroidism. (Funded by European Union FP7 and others; TRUST ClinicalTrials.gov number, NCT01660126 .)
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