26-G needle-assisted sutureless glueless intrascleral haptic fixation for secondary ciliary sulcus implantation of three-piece polymethylmethacrylate intraocular lens during penetrating keratoplasty

AbstractAfter tenotomy adjoining 3 o'clock and 9 o'clock limbus, 3-mm-wide partial-thickness scleral tunnels are created at these two diametrically opposite points 3 mm from the limbus such that they reach up to a distance of 1.5 mm from the limbus. Two ab externo sclerotomies are created using 26-G needles on the bed of these partial-thickness scleral tunnels. Precaution is taken to ensure that the positions of the sclerotomies are diagonally opposite each other. A scleral niche is made using a 26-G needle to accommodate the intraocular lens (IOL) haptic later. A 7.5-mm trephine is used to excise the corneal button, and anterior vitrectomy is performed. The haptic of a three-piece polymethylmethacrylate IOL is docked in a bent 26-G needle. It is then pulled out under the partial-thickness scleral tunnel and placed securely in the scleral niche opposite to the haptic. An 8-mm donor corneal button is sutured in place using 16 equidistantly placed 10-0 nylon interrupted sutures

Physico-chemical attributes and organoleptic assessment of guava (Psidium guajava L.) cultivars grown in eastern Uttar Pradesh

A study was conducted to evaluate the different guava cultivars for their physico-chemical composition and organoleptic assessment during the year 2012-2013. Results of study indicated that Gorakh Bilas Pasand cultivar proved to be superior on the basis of physical characters (Length-7.64 cm, Breadth-7.79 cm , Weight-240.60 g, Number of seeds per fruit-251 etc.) followed by Lucknow-49. However, Lucknow-49 was found noteworthy in respect of chemical composition (TSS-13.00 oBrix, Acidity-0.50%, pH-5.86, Vitamin C-300.36 mg/100g etc). In organoleptic assessment, it was found that ‘liked very much’ rating was provided by consumer to Lucknow-49. On the basis of overall findings, it was concluded that ‘Lucknow-49’ was superior in most of characters studied and might be one of the promising cultivars for quality fruits under eastern Uttar Pradesh conditions

On q-series and continued fractions

In this paper we have established interesting results involving continued fraction. Special cases of the result established herein have also been discussed

G x E evaluation for feed barley genotypes evaluated in country by AMMI analysis

AMMI analysis of feed barley genotypes exhibited highly significant effects of environments, genotypes and interactions for both the years. The major portion of the total variance was described by the environmental effects up to 45.6% and 42.3% in respective years. The genotypes effects contributed marginally as of only 8.6% and 6.9% of total variation. The significant interaction effects were partitioned into IPCA1, IPCA2 , IPCA3 and IPCA4; which explained upto 42.4, 18.3, 9.7 and 8.1% of the first year and 32.2, 20.3, 15.6 and 10.5% for second year. The cumulative effect of first two interaction principal components comes out to 60.7% and 52.3% respectively. Maximum genotype yield during study period varied from 49.8 to 48 whereas the lowest yield ranged from 37 to 36.4 q/ha. AMMI stability index identified genotypes G9(BH 972), G15(JB 274) for former and G23(DWRB 109) & G2(KB 1205) for latter year. AMMI distance marked G15(JB 274) & G7(NDB 1561) for first and genotypes G26(UPB 1034) & G23(DWRB 109) for the second year. Desirable genotypes for selection would be G11(PL 871), G27(PL 872) and G23(DWRB 109), G20(BH 946) for respective years a per the GSI score. Genotypes with IPCA-1 scores close to zero identified G1(PL 751), G9(BH 972) and G27(PL 872 ) for first year and G5(RD 2786), G4(NDB 1554) and G24 (UPB 1036) for second year would have wider adaptation to the tested environments as per AMMI graphical plots

Posterior migration of Ahmed glaucoma valve tube in a patient with Reiger anomaly: a case report

BACKGROUND: To describe, a yet non-documented complication of GDI surgery (glaucoma drainage incision surgery) - anterior to posterior segment migration of Ahmed Glaucoma Valve (AGV) tube. CASE PRESENTATION: We report a young 9 year old boy, diagnosed with refractory glaucoma with Reiger anomaly. History included of poor vision in both eyes, left more than right with glare since childhood. He underwent GDI surgery with AGV implantation following which he developed posterior migration of AGV tube. The detailed ocular history, ophthalmic findings, clinical course, surgical management and development of the posterior tube migration is discussed. CONCLUSION: Posterior Migration of AGV tube has yet not been described. Also there is a role of expectant management of the complication in this case as evidenced by the benign course of events

Operational Challenges in Diagnosing Multi-Drug Resistant TB and Initiating Treatment in Andhra Pradesh, India

Revised National TB Control Programme (RNTCP), Andhra Pradesh, India. There is limited information on whether MDR-TB suspects are identified, undergo diagnostic assessment and are initiated on treatment according to the programme guidelines.To assess i) using the programme definition, the number and proportion of MDR-TB suspects in a large cohort of TB patients on first-line treatment under RNTCP ii) the proportion of these MDR-TB suspects who underwent diagnosis for MDR-TB and iii) the number and proportion of those diagnosed as MDR-TB who were successfully initiated on treatment.A retrospective cohort analysis, by reviewing RNTCP records and reports, was conducted in four districts of Andhra Pradesh, India, among patients registered for first line treatment during October 2008 to December 2009.Among 23,999 TB patients registered for treatment there were 559 (2%) MDR-TB suspects (according to programme definition) of which 307 (55%) underwent diagnosis and amongst these 169 (55%) were found to be MDR-TB. Of the MDR-TB patients, 112 (66%) were successfully initiated on treatment. Amongst those eligible for MDR-TB services, significant proportions are lost during the diagnostic and treatment initiation pathway due to a variety of operational challenges. The programme needs to urgently address these challenges for effective delivery and utilisation of the MDR-TB services

Development and Validation of UV-Visible Spectrophotometric Baseline Manipulation Method for Simultaneous Quantitation of Tenofovir Disoproxil Fumarate and Emtricitabine in Pharmaceutical Dosage Form

A simple, economical, precise, and accurate new UV-visible spectrophotometric baseline manipulation method for simultaneous determination of tenofovir disoproxil fumarate (TE) and emtricitabine (EM) in combined tablet dosage form has been developed. e method is based on baseline manipulation (difference) spectroscopy where amplitudes at 261 and 289.9 nm were selected to determine TE and EM, respectively, in combined formulation, and distilled water was used as solvent. Both drugs obey Beer's law in the concentration ranges of 4-20 g/mL for TE and 6-30 g/mL for EM. e results of analysis have been validated statistically, and recovery studies con�rmed the accuracy of the proposed method which was carried out by following the ICH guidelines

Calibration of VELC detectors on-board Aditya-L1 mission

Aditya-L1 is the first Indian space mission to explore the Sun and solar atmosphere with seven multi-wavelength payloads, with Visible Emission Line Coronagraph (VELC) being the prime payload. It is an internally occulted coronagraph with four channels to image the Sun at 5000 \AA~ in the field of view 1.05 - 3 \rsun, and to pursue spectroscopy at 5303 \AA, 7892 \AA~ and 10747 \AA~ channels in the FOV (1.05 - 1.5 \rsun). In addition, spectropolarimetry is planned at 10747 \AA~ channel. Therefore, VELC has three sCMOS detectors and one InGaAs detector. In this article, we aim to describe the technical details and specifications of the detectors achieved by way of thermo-vacuum calibration at the CREST campus of the Indian Institute of Astrophysics, Bangalore, India. Furthermore, we report the estimated conversion gain, full-well capacity, and readout noise at different temperatures. Based on the numbers, it is thus concluded that it is essential to operate the sCMOS detectors and InGaAs detectors at $-5^{\circ}$ and $-17^{\circ}$ C, respectively, at the spacecraft level.Comment: Accepted for publication in Experimental Astronomy; 13 Pages, 5 Figures and 8 Table

Quantifying tropical cyclone's effect on the biogeochemical processes using profiling float observations in the Bay of Bengal

Physical and biogeochemical observations from an autonomous profiling Argo float in the Bay of Bengal show significant changes in upper ocean structure during the passage of Tropical Cyclone (TC) Hudhud (7–14 October 2014). TC Hudhud mixed water from a depth of about 50 m into the surface layers through a combination of upwelling and turbulent mixing. Mixing was extended into the depth of nutricline, the oxycline and the subsurface‐chlorophyll‐maximum; thus had a strong impact on the biogeochemistry of the upper ocean. Before the storm, the near‐surface layer was nutrient depleted and was thus oligotrophic with the chlorophyll‐a concentration of less than 0.15 mg m‐3. Storm mixing initially increased the chlorophyll by 1.4 mg m‐3, increased the surface nitrate concentration to about 6.6 μM kg‐1, and decreased the sub‐surface dissolved oxygen (30–35 m) to 31 % of saturation (140 μM). These conditions were favorable for phytoplankton growth resulting in an estimated increase in primary productivity averaging 1.5 g C m‐2 day‐1 over 15 days. During this bloom, chlorophyll‐a increased by 3.6 mg m‐3, and dissolved oxygen increased from 111 % to 123 % of saturation. Similar observations during TC Vardah (6–12 December 2016) showed much less mixing. Our analysis suggests that relatively small (high) translation speed and presence of cold (warm) core eddy leads to strong (weak) oceanic response during TC Hudhud (TC Vardah). Thus, although cyclones can cause strong biogeochemical responses in the Bay of Bengal, the strength of response depends on the properties of the storm and the prevailing upper ocean structure such as presence of mesoscale eddies