Morbidity Pattern Among Out-Patients Attending Urban Health Training Centre in Srinagar

The current study was designed to identify the morbidity pattern of out-patients attending Urban Health Training Centre in an urban area of a medical college in Srinagar, Pauri Garhwal district, Uttarakhand, North India. The present study record-based retrospective study was conducted among the out-patients attending the regular clinic at the Urban Health Training Centre, of a medical college in Srinagar city of Uttarakhand State of North India during the study period of one year in 2014. Data was retrieved from the OPD registers maintained at the clinic. Data was collected pertaining to socio-demographic profile, morbidity details and treatment pattern. Diseases were identified using the International Classification of Diseases (ICD-10) code. Descriptive analysis was done. During the study period, a total of 9343 subjects attended the OPD. Among them, majority of them (60%) were females. More than half (56 %) belonged to the age group of 35-65 year age-group. The association of disease classification was found to be statistically significant with respect to gender. The leading morbidity of communicable disease was found to be certain infectious and parasitic diseases especially Typhoid whereas musculoskeletal system and connective tissue disorders were the most common cause among morbidity due to NCDs. Out of all, typhoid was found to cause maximum of morbidity among the subjects. The present study highlights the morbidity pattern of communicable and NCDs among the population of hilly areas of Garhwal, Uttarakhand India. Priority should be preferred for the regular tracking of diseases in terms of preventive and promotive aspects. Morbidity in the out- door clinics reflects the emerging trend of mixed disease spectrum burden comprising communicable and non-communicable diseases

Artificial Immune System based Firefly Approach for Web Page Classification

WWW is now a famous medium by which people all around the world can spread and gather the information of all kinds. But web pages of various sites that are generated dynamically contain undesired information also. This information is called noisy or irrelevant content. Web publishing techniques create numerous information sources published as HTML pages. Navigation panels, Table of content, advertisements, copyright statements, service catalogs, privacy policies etc. on web pages are considered as relevant and irrelevant content. This paper discusses various methods for web pages classification and a new approach for content extraction based on firefly feature extraction method with danger theory for web pages classification

Drug utilization study in patients of COPD in TB and Chest department in a tertiary care teaching hospital

Background: Chronic Obstructive Pulmonary Disease (COPD) is a major cause of chronic morbidity and mortality throughout the world. It is the fourth leading cause of death in the world, and further increase in its prevalence and mortality can be predicted in the coming decades. Many people die prematurely from it or its complications. Total deaths from COPD are projected to increase by more than 30% in the next 10 years unless urgent action is taken to reduce the underlying risk factors, especially tobacco use. Estimates show that in 2020 COPD will become the third leading cause of death worldwide. A wide range of drugs are prescribed for COPD but not strictly according to established guidelines.Methods: A prospective observational study of drugs prescribed in COPD was conducted in outdoor patients at TB and Chest department at Sheth L. G. General Hospital.Results: Total 90 prescriptions of COPD patient were collected and studied for drug utilization. The results revealed that the ratio of prevalence in males was higher than females, which was 73% and 27% respectively. Theophylline (93.3%) and chlorpheniramine (71.1%) were most prescribed drugs.Conclusions: According to the results, prevalence was higher in males than females and was higher in smokers than nonsmokers and most common prescribed class of drug was methylxanthine

TransEdge: Supporting Efficient Read Queries Across Untrusted Edge Nodes

We propose Transactional Edge (TransEdge), a distributed transaction processing system for untrusted environments such as edge computing systems. What distinguishes TransEdge is its focus on efficient support for read-only transactions. TransEdge allows reading from different partitions consistently using one round in most cases and no more than two rounds in the worst case. TransEdge design is centered around this dependency tracking scheme including the consensus and transaction processing protocols. Our performance evaluation shows that TransEdge's snapshot read-only transactions achieve an 9-24x speedup compared to current byzantine systems

Green Manufacturing: Case Study using AHP and Grey Relation

Green manufacturing is cooperative manufacturing based on various hierarchy resources. Its important to get the optimum Cooperative enterprise scheme by analyzing, arranging and evaluating the manufacturing capabilities of Industries for Green manufacturing. The paper analyzes correlation between five industries in the context of green manufacturing, with the help of relation matrix which is based on grey relation theory and AHP method. The paper analyses the environmental actions according to Green product design, Green design of raw material, Green process, Green Technology, Green packaging Material and Green Packaging design

Mesenchymal stromal cells, metabolism, and mitochondrial transfer in bone marrow normal and malignant hematopoiesis

Hematopoietic stem cell (HSC) transplantation-based treatments are in different phases of clinical development, ranging from current therapies to a promise in the repair and regeneration of diseased tissues and organs. Mesenchymal stromal/stem cells (MSCs), which are fibroblast-like heterogeneous progenitors with multilineage differentiation (osteogenic, chondrogenic, and adipogenic) and self-renewal potential, and exist in the bone marrow (BM), adipose, and synovium, among other tissues, represent one of the most widely used sources of stem cells in regenerative medicine. MSCs derived from bone marrow (BM-MSCs) exhibit a variety of traits, including the potential to drive HSC fate and anti-inflammatory and immunosuppressive capabilities via paracrine activities and interactions with the innate and adaptive immune systems. The role of BM-MSC-derived adipocytes is more controversial and may act as positive or negative regulators of benign or malignant hematopoiesis based on their anatomical location and functional crosstalk with surrounding cells in the BM microenvironment. This review highlights the most recent clinical and pre-clinical findings on how BM-MSCs interact with the surrounding HSCs, progenitors, and immune cells, and address some recent insights on the mechanisms that mediate MSCs and adipocyte metabolic control through a metabolic crosstalk between BM microenvironment cells and intercellular mitochondrial transfer in normal and malignant hematopoiesis