Induction process of trainees in pathology residency

This article describes the evolution of the induction process of pathology residency at The Aga Khan University hospital. The Department of Postgraduate Medical Education was established in 1985. The induction process is an exhaustive exercise that includes an admission test held simultaneously in Karachi, Hyderabad, Lahore, and Rawalpindi, followed by an interview of the shortlisted candidates. The pathology residency program was started 25 years ago and since then the induction process has undergone major changes with the course of time

Tailored metabolic workup for urolithiasis – the debate continues

Abstract Urolithiasis is one of the commonest afflictions of the urinary tract. Stones are of various chemical compositions, some share some common etiology; but most are specific to the structure and composition of stone. In view of highly recurrent nature of this condition, it is logical to have strategies for prevention. However, due to multiple factors most patients receive no or fragmented information on prevention. The current controversy is to the extent of metabolic workup in adult first time stone former. This requires longitudinal studies to show benefit in prevention strategies. Patients at high risk can have recurrence in weeks to years, depending upon the composition and attending risk factor. They should be targeted with concentric and tailored prevention protocols. The major urological guidelines (EAU and AUA) recommend basic stone workup for all patients. However, indication for detailed workup are less well documented, so one potential solution is to tailor metaphylaxis strategies for individual patient

Determination of delay in burn around time (TAT) of stat tests and its causes: an AKUH experience.

Abstract Objective: To evaluate the delay and reasons of delay of turnaround time (TAT) of stat tests in the section of clinical chemistry of the clinical laboratory. Setting: Clinical Laboratory, Aga Khan University Hospital, Karachi. Patients and Methods: In our study turn around time (TAT) of stat tests were analyzed. Turn around time was specified as the time from receipt of the sample till the final verification of results (sample receipt time to result verification time). Delays were categorized into 15 minutes, 16-30 minutes, 31 to 60 minutes and \u3e60 minutes. It was also noted as to which time of the day was delay in reporting stat results occurred. Reasons for the delay were also looked ihto. Results: Total 20079 stat samples were received from August 2001 till October 2001. Four hundred eight (2.03%) samples were reported after the acceptable turnaround time. Cumulative analysis of the excess TAT of stat tests showed that 0-15 minutes delay was noted in 68 (16.7%) samples, 16-30 minutes delay in 80(19.6%) samples, 31-60 minutes delay in 76 (18.6%) samples and more than 60 minutes delay in 185 (45.3%) of samples. Most of the delay in reporting of stat test in three months time was surprisingly noted in the morning shift. Overall delay in reporting in morning shift was found to be of 242 (59.3 %) samples. In the evening and night shift 83 (20.3%) and 82 (20.1%) samples respectively were found to be delayed. Reasons for delay in TAT were as follows: n = 163 (40%) due to machine breakdown, n=147(36 %) due to delay in the maintenance of analyzers, n=73 (18 %) due to overlook of the staff during shift change (e.g. night shift to morning shift) and n= 25 (6%) due to computer shutdown. Conclusion: We conclude that most of the delay in TAT of stat tests in our laboratory occurred for more than 60 minutes and was frequently seen in the morning shift. It was also noticed that machine breakdown was the most common reason for this delay. Regular audit of such data helps in the evaluation of the efficiency of the laboratory and hence corrective measures taken accordingly would be helpful in providing better service to the physicians and patients (JPMA 53:65;2003)

Comparison of two methods (precipitation manual and fully automated enzymatic) for the analysis of HDL and LDL cholesterol

Objective: To compare accuracy and throughput time for the measurement of HDL and LDL cholesterol by manual precipitation and fully automated enzymatic methods. Methods: Fifty, serum samples collected over a 4 months period (February - May 2004) were analyzed for HDL and LDL cholesterol by two different methods i.e. precipitation manual and automatic enzymatic method in the section of chemical pathology, Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi Pakistan. Results: The mean standard deviation for HDL Cholesterol by precipitation method and automated method were 43.12 +/- 8.97mg/dl and 43.86 +/- 10.34mg/dl respectively (p-value = 0.301). The mean standard deviation for LDL cholesterol by precipitation method and automated method were 111.76 +/- 25.57mg/dl and 111.8 +/- 28.41mg/dl respectively (p-value = 0.981). The calculated t and F value for HDL-C was 0.0172 and 0.75 respectively, and calculated t and F values for LDL-C were 0.047 and 0.809 respectively. Average time for manual method was 45 minutes and automation 20 minutes. Conculsion: Both the precipitation (manual) method and the automated method provide reliable, precise and accurate results. In both the methods t and F values were less than critical. Automated method provide high throughput and are less labor intensive. The choice of method can depend on laboratory facilities and workloa

Impact of COVID-19 on laboratory professionals-A descriptive cross sectional survey at a clinical chemistry laboratory in a developing country

Background: The lab professionals at one end are at increased risk of contracting the infection while on the other end have to deal with the various challenges during the Coronavirus Disease 2019 (COVID-19) outbreak. This survey was undertaken to analyze the lab professionals\u27 perspectives, in terms of the challenges, financial implications, fears, motivation and satisfaction from organizational processes and policies adopted, amid the COVID-19 crisis.Material & methods: The study utilized a cross-sectional survey design. The survey was administered online via the google docs survey tool from medical laboratory professionals (n = 64) serving at the section of Clinical Chemistry, department of Pathology and Laboratory Medicine, the Aga Khan University (AKU), Pakistan from June 4th to 14th 2020. A team consisting of three Clinical Chemistry consultants serving as faculty at the section, designed the survey questionnaire. The responses were recorded on a five-point Likert Scale (1 = strongly disagree, 2 = disagree, 3 = neutral, 4 = agree and 5 = strongly agree). The statistical analysis was performed using the Microsoft Excel 2013. Frequency and percentages were calculated for gender, experience and designation while descriptive results based on the responses were also recorded.Results: The response rate was 78% (n = 50). 60% responded that the current lifestyle adopted during the pandemic was not better than the traditional one. The fear of employment termination and financial challenges were being faced by 42% and 78% respondents respectively. The quality of family life was improved in 54% cases while 96% were of the view that their social activities at work have suffered. Whereas, 22% were not satisfied by the measures taking by the management during the outbreak.Conclusion: The findings of this survey provide laboratorians\u27 perspective, in times of such crisis and provides us certain lessons to prepare for such unpredicted situations in future

People Without History

The West has become obsessed with Muslims, constantly classifying them as either 'moderate' or 'extreme'. Reacting against this dehumanising tendency, Jeremy Seabrook and Imran Ahmed Siddiqui show us the daily life of poor Muslims in India and sheds light on what lies behind India's 'economic miracle'. The authors examine life in Muslim communities in Kolkata, home to some of the most disadvantaged people in India, giving a voice to their views, values and feelings. We see that Muslims are no different from those of other faiths - work, family and survival are the overwhelming preoccupations of the vast majority. Although most are observant in their religion, there is no trace of the malevolence or poverty-fuelled extremism attributed to them. This enlightening and elegantly written book will be of great interest to students and practitioners of development and anyone who wants a more realistic picture of Muslim life and modern India

STRUCTURAL PROPERTIES OF NITROGEN DOPED ANATASE AND RUTILE TiO2 THIN FILMS

Anatase and rutile TiO2 thin films have been doped by N ion implantation. The effect of N doping on the structural changes of TiO2 thin films and its correlation to the optical and chemical properties of the films is investigated. The depth and concentration of the implanted N atoms is found not to exhibit substantial difference for anatase and rutile phases. The energy loss of the implanted N atoms correlates well to the energy gained by O and Ti atoms in the TiO2 lattice. An increased number of O vacancies are found to be generated as compared to Ti for both anatase and rutile phases. The energy loss mechanisms of the implanted N atoms together with the O vacancy generation are found to be the major driving forces for facilitating enhanced optical and chemical properties of the TiO2 thin films

Determination of Yearly Wind Energy Potential and Extraction of Wind Energy Using Wind Turbine for Coastal Cities of Baluchistan, Pakistan

04 March, 2019 Accepted: 24 April, 2019Abstract: Wind energy assessment of Ormara, Gwadar and Lasbela wind sites which are located in provinceBaluchistan is presented. The daily averaged wind speed data for the three sites is recorded for a period of four yearsfrom 2010-2013 at mast heights 7 m, 9.6 m and 23 m. Measured wind data are extrapolated to heights 60 m (Ormara),80 m (Gwadar) and 60 m (Lasbela). Yearly averaged wind speeds are modeled using a two parameters Weibullfunction whose shape (k) and scale (c) parameters are computed using seven well known numerical iterative methods.Reliability of the fitting process is assessed by employing three goodness-of-fit test statistics, namely, RMSE, R2 and χ2tests. Tests indicate that MLE, MLM and EPFM outperformed other Weibull parameter estimation methods for a betterfit behavior. Yearly Weibull pdf and cdf are obtained and Weibull wind characteristics are determined. Wind turbinesEcotecnia 60/1.67 MW and Nordex S77 1500 kW are used to extract wind energy on yearly basis. Estimated yearlyWeibull power densities are in the range 623.00 - 700.13 W/m2, 276.04 – 307.55 W/m2 and 66.85 – 75.93 W/m2 forOrmara, Gwadar and Lasbela respectively. Extracted wind energy values for Ormara and Gwadar using wind turbinesare reported as ca. 8623 kWh and ca. 4622 kWh, respectively