671 research outputs found
Non classical effects in planar waveguides
The quantum description of light propagation inside a planar waveguide is given. In particular, the description describes the behavior of the field inside a directions coupler. Nonclassical effects are presented and discussed
Properties of entangled photon pairs generated in one-dimensional nonlinear photonic-band-gap structures
We have developed a rigorous quantum model of spontaneous parametric
down-conversion in a nonlinear 1D photonic-band-gap structure based upon
expansion of the field into monochromatic plane waves. The model provides a
two-photon amplitude of a created photon pair. The spectra of the signal and
idler fields, their intensity profiles in the time domain, as well as the
coincidence-count interference pattern in a Hong-Ou-Mandel interferometer are
determined both for cw and pulsed pumping regimes in terms of the two-photon
amplitude. A broad range of parameters characterizing the emitted
down-converted fields can be used. As an example, a structure composed of 49
layers of GaN/AlN is analyzed as a suitable source of photon pairs having high
efficiency.Comment: 14 pages, 23 figure
EGF Receptor Signaling Is Essential for K-Ras Oncogene-Driven Pancreatic Ductal Adenocarcinoma
SummaryClinical evidence indicates that mutation/activation of EGF receptors (EGFRs) is mutually exclusive with the presence of K-RAS oncogenes in lung and colon tumors. We have validated these observations using genetically engineered mouse models. However, development of pancreatic ductal adenocarcinomas driven by K-Ras oncogenes are totally dependent on EGFR signaling. Similar results were obtained using human pancreatic tumor cell lines. EGFRs were also essential even in the context of pancreatic injury and absence of p16Ink4a/p19Arf. Only loss of p53 made pancreatic tumors independent of EGFR signaling. Additional inhibition of PI3K and STAT3 effectively prevented proliferation of explants derived from these p53-defective pancreatic tumors. These findings may provide the bases for more rational approaches to treat pancreatic tumors in the clinic
Squeezed-light generation in a nonlinear planar waveguide with a periodic corrugation
Two-mode nonlinear interaction (second-harmonic and second-subharmonic
generation) in a planar waveguide with a small periodic corrugation at the
surface is studied. Scattering of the interacting fields on the corrugation
leads to constructive interference that enhances the nonlinear process provided
that all the interactions are phase matched. Conditions for the overall phase
matching are found. Compared with a perfectly quasi-phase-matched waveguide,
better values of squeezing as well as higher intensities are reached under
these conditions. Procedure for finding optimum values of parameters for
squeezed-light generation is described.Comment: 14 pages, 14 figure
Thermal Physiology and Developmental Plasticity of Pigmentation in the Harlequin Bug (Hemiptera: Pentatomidae)
Traits that promote the maintenance of body temperatures within an optimal range provide advantages to ectothermic species. Pigmentation plasticity is found in many insects and enhances thermoregulatory potential as increased melanization can result in greater heat retention. The thermal melanism hypothesis predicts that species with developmental plasticity will have darker pigmentation in colder environments, which can be an important adaptation for temperate species experiencing seasonal variation in climate. The harlequin bug (Murgantia histrionica, Hemiptera: Pentatomidae, Hahn 1834) is a widespread invasive crop pest with variable patterning where developmental plasticity in melanization could affect performance. To investigate the impact of temperature and photoperiod on melanization and size, nymphs were reared under two temperatures and two photoperiods simulating summer and fall seasons. The size and degree of melanization of adults were quantified using digital imagery. To assess the effect of coloration on the amount of heat absorption, we monitored the temperature of adults in a heating experiment. Overall, our results supported the thermal melanism hypothesis and temperature had a comparatively larger effect on coloration and size than photoperiod. When heated, the body temperature of individuals with darker pigmentation increased more relative to the ambient air temperature than individuals with lighter pigmentation. These results suggest that colder temperatures experienced late in the season can induce developmental plasticity for a phenotype that improves thermoregulation in this species. Our work highlights environmental signals and consequences for individual performance due to thermal melanism in a common invasive species, where capacity to respond to changing environments is likely contributing to its spread
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