Sino-Iranian Legal Implication on Investment Cooperation

由于技术革新造成的快速发展，在经济上和日常生活中，经济合作已经是另一种的合作方式。在世界关系下，经济合作有了需要法律分析和兼容法制界限的特征。 对于两个有共同「友好」利益的国家，若符合双方的利益及现实上的要求，经济合作便是一件很正常的事。 在整个地区，制裁救济会允许中国公司在石油部门的贸易和投资已达到更大的利益。因为收到了石油，北京把伊朗市场从各阶层消费品特别是非石油部门，像建造业、制造业和交通业建立了良好的关系。 通过亚洲基础设施投资银行，中国赞助国际金融机构为了投资于基础设施项目在亚洲-太平洋地区、在陆基的「新丝绸之路」和「海上丝绸之路」，伊朗成为了合作国家其中一个很重要的国度。伊朗...Since the fast development due to technological innovations, economic cooperation is just another threshold in the economic space and daily reality, it becomes the most common features in World relations which simultaneously needs legal analyzes and compatible legal boundaries. For two ‘friendly’ countries, who share common values it is normal that there will also be an economic cooperation, if...学位：法学硕士院系专业：法学院_民商法学学号：1292014115448

The Impact of Pictorial Representations in Teaching Math Word Problems to a Child with Autism

The study used a single subject A-B-A research design because it used one subject, an 18-year old boy participant who was diagnosed with having higher spectrum Autism (Asperger). The investigator examined the effect of pictorial representations of math word problems on the participant’s performance in solving one step, two steps, and three steps math word problems. The investigator found that the use pictorial representations improved the participant’s math achievement in solving math word problems. The investigator also found that the participant had difficulty understanding words with mathematical connotations

Cross talk between gut microbiome and skeletal muscle mass

Dear Editor-in-ChiefThe topic of the interaction between gut microbiota and skeletal muscle and its influence on the regulation of muscle mass is new. There is evidence that the composition and diversity of gut microbiota plays a role in skeletal muscle metabolism and function, especially in catabolic (sarcopenia and cachexia) or anabolic (exercise or in athletes) situations. Signals generated by gut-microbiota interactions, such as microbial metabolites, gut peptides, lipopolysaccharides, and interleukins, modulate systemic inflammation and insulin sensitivity, which in turn regulate muscle function.Potential mechanisms by which the gut microbiota can affect muscle mass suggest that it can regulate the sensitivity of skeletal muscle to anabolic stimuli and contribute to the reduction or increase of muscle mass depending on the physiological state.In addition, the use of probiotic strategies to prevent muscle mass loss or promote muscle mass gain in catabolic or anabolic states may be helpful. Probiotics, particularly lactic acid bacteria and bifidobacteria, have shown potential in limiting sarcopenia, cachexia, or promoting muscle health and function in rodent studies. However, more research is needed to identify specific strains that can optimize muscle mass and performance in humans (Chew et al., 2023).Overall, this line of research suggests that a combination of strategies, including probiotics, personalized nutrition, and traditional supplementation, may be the best approach to maintaining muscle function in people of all ages. However, further studies are needed to better understand the role of gut microbiota in muscle metabolism and to identify optimal probiotic strategies for muscle health.Researchers in this field also discuss challenges in studying the effects of probiotics on muscle mass and function, including variations in study design, participant characteristics, and measurement methods. They suggest future research directions, such as investigating the use of strict anaerobic bacteria and a mixture of probiotics or fecal microbiota transplantation (FMT) to more efficiently colonize the host's microbial ecosystem. In addition, they suggest the combination of probiotic strains with other nutritional agents to optimize their effects on the microbiota and muscles (Gizard et al., 2020).Consequently, while probiotics have shown promising effects on muscle mass and performance in animal studies, their efficacy in humans remains unclear. Further research is needed to determine specific strains and protocols that can effectively modulate gut microbiota and improve muscle health in different populations

A comparative study on the influence of kinesio taping® and laser therapy on knee joint position sense, pain intensity, and function in individuals with knee osteoarthritis

زمینه و هدف: روش های توانبخشی محافظه کارانه بخش مهمی از درمان مبتلایان به استئوآرتریت زانو محسوب می شوند. هدف از این مطالعه بررسی تأثیر کینزیوتیپینگ و لیزر کم توان بر شدت درد، عملکرد و حس وضعیت زانو در این بیماران بود. روش بررسی: در این مطالعه نیمه تجربی، تعداد 26 بیمار (میانگین ± انحراف معیار سن: 6/4±5/48 سال) مرد مبتلا به استئوآرتریت یکطرفه زانو به صورت تصادفی به 2 گروه کینزیوتیپینگ (13 نفر) و لیزر کم توان (13 نفر) تقسیم شدند. هر 2 گروه در مدت زمان 10 جلسه علاوه بر درمان معمول فیزیوتراپی، پروتکل درمانی مخصوص به خود را دریافت نمودند. برای ارزیابی شدت درد، عملکرد و حس وضعیت زانو به ترتیب از مقیاس بصری سنجش درد، آزمون برخاستن و راه رفتن و روش بازسازی زاویه هدف در ابتدا و پس از اعمال مداخله درمانی استفاده شد. یافته ها: هر 2 روش به طور معنی داری باعث کاهش شدت درد، کاهش مدت زمان انجام آزمون برخاستن و راه رفتن و کاهش خطای بازسازی زاویه 60 درجه فلکشن زانو شدند (001/0P<). تغییرات میانگین خطای بازسازی زاویه هدف به طور معنی داری در گروه کینزیوتیپینگ بیشتر از گروه لیزر درمانی بود (001/0P<)، در حالی که تفاوت میانگین سایر متغیرها بین 2 گروه معنی دار نبود (05/0P>). نتیجه گیری: کینزیوتیپینگ و لیزر کم توان می توانند باعث بهبود درد، حس وضعیت زانو و عملکرد افراد مبتلا به استئوآرتریت زانو شوند؛ اگرچه اثر کینزیوتیپینگ در بهبود حس وضعیت زانو بیشتر است

Effects of exercise on reverse cholesterol transport: A systemized narrative review of animal studies

Reverse Cholesterol Transport (RCTr) is the mechanism by which excess cholesterol from peripheral tissues is transported to the liver for hepatobiliary excretion, thereby inhibiting foam cell formation and the development of atherosclerosis. Exercise affects RCTr, by influencing high-density lipoprotein cholesterol (HDL) through remodeling and by promoting hepatobiliary sterol excretion. The objectives of this systematized review of animal studies is to summarize the literature and provide an overview of the effects of chronic exercise (at least two weeks) on apolipoproteins (Apo A-I, Apo-E), Paraoxonase-1 (PON1), ATP-binding cassette transporters (ABCA1, ABCG1, ABCG4, ABCG5, ABCG8), scavenger receptor class B type I (SR-BI), cholesteryl ester transfer protein (CETP), low-density lipoprotein receptor (LDLr) and cholesterol 7 alpha-hydroxylase (CYP7A1) and Niemann-Pick C1-like 1 (NPC1L1). Three electronic databases (PubMed, Science Direct and Google Scholar) were searched for eligible studies conducted from the earliest available date to August 2018. Most of studies investigate the effects of low to moderate intensity aerobic training on RCTr elements. The majority were on exercised rats undertaking moderate intensity aerobic training. This review highlights that moderate intensity and longer-term training has a greater effect on RCTr elements than low intensity training. There a few studies examining high intensity training which warrants further investigation. [Abstract copyright: Copyright © 2019. Published by Elsevier Inc.

The effect of aerobic exercise training on the expression of genes involved in cardiac apoptosis (Caspase-3/-7) in rats with glioblastoma multiforme

Performing aerobic exercise in different disease conditions can regulate cardiac homeostasis and reduce cardiac apoptosis caused by the disease. In brain cancer, other tissues, including cardiac tissue, can also be affected. Since exercise training causes organ crosstalk, in this study, the effects of aerobic exercise training (AET) on cardiac apoptosis in Glioblastoma multiforme (GBM) rats are evaluated. Twenty-four male Wistar rats were divided into 3 groups (n=8 in each) of healthy control, GBM, and GBM+AET. Glioblastoma was injected into the frontal cortex of rats. The training group (AET) performed aerobic exercises on the treadmill for 4 weeks, 3 days a week at a speed of 18 meters per minute, for 25-40 minutes. In the end, the rats were sacrificed and caspase-3 and caspase-7 were analyzed from the myocardium by Real-time PCR method. Considering H&E image, the GBM group showed necrosis and apoptosis in cardiac tissue compared to the healthy group. Compared to the healthy control group, GBM significantly increased caspase-3 and caspase-7 mRNA in the myocardium (p<0.05). However, in contrast to the GBM group, the GBM+AET showed a significant decrease in caspase-3 and caspase-7 mRNA at the myocardium (p<0.05). Since tumor formation in the body can affect other distant tissues in an endocrine manner, it is suggested to prioritize aerobic exercise to control the damage caused by GBM on heart tissue. However, more studies are needed, especially on human samples

Effects of 8-Week Suspension Training Program on Physical Fitness, Biomechanical Lower Extremity Injury Risk Factors, Mental Health, and Work-Related Factors in Navy Personnel:Protocol for a Randomized Controlled Trial

Background: Military personnel need to be in optimal physical fitness and ready for action. Currently used physical training programs are mainly based on cardiovascular routines that do not fulfill all physical requirements. Feasible and easy-accessible training programs are needed to improve strength-related physical performance.Objectives: The current study aims to investigate the effectiveness of a suspension-training program with the total body resistance exercise band in physical fitness, biomechanical lower extremity injury risk factors, mental health, and work-related factors in navy personnel.Methods: To conduct this parallel-group randomized controlled trial, 50 young men aged 18 to 28 years will be recruited. The intervention group performs suspension training (three times a week for 8 weeks) in addition to their daily duties; however, the control group continues their daily duties. The primary outcome is physical performance. The secondary outcomes include biomechanical lower extremity injury risk factors, mental health, and work-related factors.Discussion: This study aims to evaluate the effectiveness of a randomized controlled trial of suspension training in performance, lower extremity frontal plane kinematics, job satisfaction, workability, and quality of life in navy personnel. This trial might provide new insights for various experts and military coaches and suspension-training programs can be used as new methods to meet all military personnel demands with minimum facilities

Exosomes and other extracellular vesicles in response to exercise intervention: Organ crosstalk in health and diseases

Dear Editor-in-ChiefExosomes contain regulatory signals such as growth factors, miRNAs, lipids, proteins, and nucleic acids that can be transported to adjacent or distant cells to affect the target tissue under both physiological and pathological conditions (Isaac et al., 2021). Exosomes are involved in various stages of disease control including apoptosis, immune regulation, angiogenesis, cell migration and cell proliferation. Exosomes are a ubiquitous, evolutionarily conserved mechanism of cellular communication. They play important roles in healthy physiological functions. Proteins, metabolites, and nucleic acids delivered by exosomes to recipient cells effectively modulate their biological response. Such exosome-mediated responses can promote or inhibit disease. The intrinsic properties of exosomes in regulating complex intracellular pathways have increased their potential application in the therapeutic control of many diseases, including neurological conditions and cancer.Many agents are involved in modulating exosomes and other extracellular vesicles gene expression and release. One of these agents is the mechanical stress caused by exercise training. Exercise with its mechanical and oxidative stress can disrupt cell homeostasis and create adaptations at the molecular and cellular level to improve physiological health, which is effective in prevention of different diseases. Exercise by activation of all organs of the body, especially skeletal muscle, promotes the release of exosomes, through which it can develop organ crosstalk and have beneficial effects at the cellular level. It has been show that exercise promotes the release of exosomes without modification of its vesicle size (Estebanez et al., 2021). Little current data suggests that exosomes are released into the circulation in an intensity-dependent manner in response to acute endurance exercise. Many of the currently reported myokines/exerkines are also produced from exosomes. Finally, exosomes within skeletal muscle are depleted in response to an acute bout of endurance exercise (Safdar & Tarnopolsky, 2018)