Alcohol and healthy ageing: a challenge for alcohol policy

Objectives: This paper presents findings of a qualitative study of older people's use of alcohol during retirement and identifies ways that an improved understanding of older people's drinking can inform policy approaches to alcohol and active and healthy ageing. Study design: Qualitative semi-structured interviews conducted with a self-selecting sample of retired people. Methods: Participants were recruited from three geographical locations in the West of Scotland. A quota sampling design was used to ensure a broad spread of participants in terms of socio-economic position, age and gender. In total 40 participants were interviewed and the data analysed thematically using Braun and Clarke's (2006) approach. Results: Amongst those who used alcohol, it was most often framed in terms of pleasure, relaxation, socialising and as a way to mark the passage of time. Alcohol was often associated with social occasions and interactions both in private and in public spaces. There were also many examples of the use of imposed routines to limit alcohol use and of a decreasing volume of alcohol being consumed as participants aged. This suggests that older people are often active in constructing what they regard as ‘healthier’ routines around alcohol use. However, processes and circumstances associated with ageing can lead to risk of social isolation and/or increased alcohol consumption. Such processes include retirement from paid work and other ‘biographical disruptions’ such as caring for a partner, bereavement and/or loss of social networks. Conclusions: These findings highlight processes that can result in changes in drinking habits and routines. Whilst these processes can be associated with a reduction or cessation of alcohol use as people age, they can also be associated with increased risk of harmful alcohol consumption. Fractured or disrupted routines, particularly those associated with bereavement or the burden of caring responsibilities, through increasing the risk of loneliness and isolation, can construct increased risk of harmful alcohol consumption. These findings reframe the pathway of risk between ageing and alcohol-related harm by highlighting the vulnerability to harmful drinking practices brought by fracture or sudden change of routine. The findings point to a role for public health in supporting the reconstruction of routines that provide structure and meaning and can be used to actively manage the benefits and harms associated with drinking

No evidence of a significant role for CTLA-4 in multiple sclerosis

Variation in the cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) gene plays a significant role in determining susceptibility to autoimmune thyroid disease and type 1 diabetes. Its role in multiple sclerosis is more controversial. In order to explore this logical candidate more thoroughly, we genotyped 771 multiple sclerosis trio families from the United Kingdom for the 3? untranslated region variable number tandem repeat, the CT60 single nucleotide polymorphism (SNP) and five haplotype-tagging SNPs. No individual marker or common haplotype showed evidence of association with disease. These data suggest that any effect of CTLA-4 on multiple sclerosis susceptibility is likely to be very small

Developing farmers’ skills and confidence in the use of Trichogramma ostriniae for European corn borer control in sweet corn, peppers, and potatoes

Numerous research and demonstration trials have shown that releases of the parasitic wasp Trichogramma ostriniae (T.ost) can be an effective management strategy for European corn borer control in sweet corn, peppers, and potatoes. It is time to put the use of T.ost into the hands of farmers. Organic farmers, farmers who do not use conventional insecticides, and high-level IPM adopters all stand to benefit from using T.ost releases as all or part of their ECB management strategy, through reduced crop damage, reduced use of insecticides, or both. Growers who are trying T.ost for the first time benefit from technical support to help make the decisions needed to get good results. An understanding of pest and beneficial biology, crop phenology, and proper release rates is needed, as well as the organizational skills to make decisions, order and release wasps, and monitor success in a timely manner. We will work closely with a minimum of 30 farmers growing sweet corn, peppers, and/or potatoes in New York, Massachusetts, Pennsylvania, and Virginia. Project staff will visit collaborating farmers each week to work with farmers to track crop phenology, decide on wasp needs for the following week, and decide where and how the releases will take place. Wasps will be supplied by the project for the first year, with farmers sharing costs the second year. Wasps are currently available commercially through IPM Laboratories in Locke, NY

Data management study, volume 5. Appendix A - Contractor data package technical description and system engineering /SE/ Final report

Technical description and systems engineering contractor data package for Voyager spacecraf

Quantized Vortex States of Strongly Interacting Bosons in a Rotating Optical Lattice

Bose gases in rotating optical lattices combine two important topics in quantum physics: superfluid rotation and strong correlations. In this paper, we examine square two-dimensional systems at zero temperature comprised of strongly repulsive bosons with filling factors of less than one atom per lattice site. The entry of vortices into the system is characterized by jumps of 2 pi in the phase winding of the condensate wavefunction. A lattice of size L X L can have at most L-1 quantized vortices in the lowest Bloch band. In contrast to homogeneous systems, angular momentum is not a good quantum number since the continuous rotational symmetry is broken by the lattice. Instead, a quasi-angular momentum captures the discrete rotational symmetry of the system. Energy level crossings indicative of quantum phase transitions are observed when the quasi-angular momentum of the ground-state changes.Comment: 12 Pages, 13 Figures, Version

Atomtronics: ultracold atom analogs of electronic devices

Atomtronics focuses on atom analogs of electronic materials, devices and circuits. A strongly interacting ultracold Bose gas in a lattice potential is analogous to electrons in solid-state crystalline media. As a consequence of the band structure, cold atoms in a lattice can exhibit insulator or conductor properties. P-type and N-type material analogs can be created by introducing impurity sites into the lattice. Current through an atomtronic wire is generated by connecting the wire to an atomtronic battery which maintains the two contacts at different chemical potentials. The design of an atomtronic diode with a strongly asymmetric current-voltage curve exploits the existence of superfluid and insulating regimes in the phase diagram. The atomtronic analog of a bipolar junction transistor exhibits large negative gain. Our results provide the building blocks for more advanced atomtronic devices and circuits such as amplifiers, oscillators and fundamental logic gates

Control of atomic currents using a quantum stirring device

We propose a BEC stirring device which can be regarded as the incorporation of a quantum pump into a closed circuit: it produces a DC circulating current in response to a cyclic adiabatic change of two control parameters of an optical trap. We demonstrate the feasibility of this concept and point out that such device can be utilized in order to probe the interatomic interactions.Comment: 5 pages, 4 figures, uses epl2.cls, revised versio