35 research outputs found

    Cu(II)-catalyzed Michael addition of 1,3-dicarbonyl compounds

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    425-42

    Metallic bismuth and aluminium: New and efficient catalysts for the preparation of various amides

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    257-259A new and efficient method for the preparation of various amides has been achieved by a simple reaction of an acid chloride with primary and secondary amines in the presence of bismuth or aluminium powder in anhydrous toluene.</span

    An efficient synthesis of 1,5-benzodiazepines catalysed by GaCl₃ under solvent free conditions

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    1463-1466Various 1,5-benzodiazepine derivatives have been synthesized from o-phenylenediamines and ketones using catalytic amount of GaCl₃ (5 mol%) under solvent free conditions. This method is facile, efficient, environmentally benign and affords 1,5-benzodiazepines in excellent yield

    Microwave enhanced, solvent free green protocol for the production of 3,4-dihydropyrimidine-2-(1<i style="">H</i>)-ones using AlCl<sub>3</sub>.6H<sub>2</sub>O as a catalyst

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    360-3633,4-Dihydropyrimidine-2-(1H)-ones are synthesized via a multicomponent reaction of aldehyde, urea or thiourea and 1,3-dicarbonyl compounds using microwave irradiation catalyzed by 10 mol% AlCl3.6H2O under solvent-free conditions. The catalyst being reported here is cheap, safe to handle and the whole procedure is eco-friendly

    ZnO Nanoparticles: An efficient green reusable catalyst for the synthesis of 3-formyl benzopyranones chalcones by Claisen-Schmidt reaction under solvent-free condition

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    1350-1354An efficient environmentally benign protocol is reported for the production of benzopyranes based chalcones. In this protocol, yield is very high, reaction time is very small, work up is very simple, catalyst can be recycled, and it is free of any hazardous by-product formation during workup

    Pyrido[2,3-<i style="mso-bidi-font-style:normal">d</i>]pyrimidines: A novel tandem Michael cyclization of 6-aminouracils with arylidenecyanoacetate using BiCl<sub>3</sub>

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    728-7321,3-Dimethyl-2,4,7-trioxo-5-aryl-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidine-6-carbonitriles have been synthesized via tandem Michael-Cyclization of 6-aminouracils with arylidene ethylcyanoacetates employing catalytic amount of BiCl3. Under mild reaction conditions, pyrido[2,3-d]pyrimidines have been obtained in very good yields in one pot

    Uncatalysed Knoevenagel condensation of 3-formylchromones in green media: Polyethylene glycol - 400 (PEG-400)

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    1743-1748An efficient, rapid and environmentally benign method for the Knoevenagel condensation of 3-formylchromones with a variety of active methylene compounds in polyethylene glycol 400 (PEG-400) under microwave irradiation (MWI) has been developed. This protocol has been found to be applicable for condensation of pharmacologically active heterocyclics such as rhodanine, creatinine, pyrazol-5-one, barbituric acid, etc. with 3-formylchromones

    Cobalt (II) chloride or manganese (II) chloride or tin (II) chloride promoted one pot synthesis of dihydropyrimidin-2(1<i style="">H</i>)-ones using microwave irradiation

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    762-767Various substituted 3, 4-dihydropyrimidin-2(1H)-ones have been synthesized in a one pot reaction of -ketoesters, aldehydes and urea using cobalt chloride hexahydrate or manganese chloride tetrahydrate or tin chloride dihydrate under microwave irradiation in excellent yields without the addition of any proton source or any additive and without any side reactions as observed by Biginelli and others
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