Social Investment. As a new charity finance tool: using both head and heart

Presenting associations between individual amino acid residues and EULAR response. (DOCX 23 kb

Summary of available serum samples in the RA biobank.

<p>Total number of patients and the classification of the samples according to the DAS time window (start and end).</p><p>Summary of available serum samples in the RA biobank.</p

Basic data elements and associated attributes per patient visit to the clinic, as in the Swedish Rheumatology Quality Registry.

<p>Basic data elements and associated attributes per patient visit to the clinic, as in the Swedish Rheumatology Quality Registry.</p

The output from a Boolean query from three sources of data.

<p>Each row correspond to samples satisfying all three criteria (C1-C3). The position column pointed to the physical location of the cells in the freezer boxes. Cell source could be either synovial fluid mononuclear cells (SFMC) or peripheral blood mononuclear cells (PBMC), and the CCP-Serum column shows the serum levels of cyclic citrullinated peptide antibody.</p><p>The output from a Boolean query from three sources of data.</p

Retrieval of cell samples according to HLA-DR type and sample date.

<p>Retrieval of cell samples according to HLA-DR type and sample date.</p

Metabolic profile of psoriasis patients.

<p>Note: The criteria were BMI>29; LDL>4.3; Triglycerides>2.6 hyperlipidemia.</p><p>Metabolic profile of psoriasis patients.</p

Retrieval of available peripheral blood mononuclear cell (PBMC) samples for each patient and the type of treatment the patient was undergoing at time of sampling.

<p>Retrieval of available peripheral blood mononuclear cell (PBMC) samples for each patient and the type of treatment the patient was undergoing at time of sampling.</p

RA patient's profile for anti-citrullinated protein antibodies (ACPA).

<p>Each column in the x-axis represents one patient with four different serum concentrations. The y-axis represents concentration levels of the different serums (CCP, Cit C1 IgG, Cit Eno IgG and Cit Fib IgG).</p

Schematic illustration of different types of database sources that need to be created for the analysis of cases (patients) versus healthy individuals (controls).

<p>Since these data are as a rule stored in different domains (clinical and research), a single case-control study needs to collect the data several times during a study, and this cycle must be repeated whenever a new case-control study is initiated.</p

T-MedFusion (service provider) and the RA CDSS communicating through the Stockholm County Council exchange index (e-index).

<p>The e-index monitors the update service from T-MedFusion. Whenever a new ACPA result arrives, the e-index sends a notification to the CDSS. The CDSS sends a GetACPAresultRequest to T-MedFusion and as response obtains ACPA results for one or several patients. Streaming of the response and request services and communications between the systems are conducted through exchange of security certificates.</p