Crystal structure of ethylenediammonium-N,N -di-3-propionic acid tetrachloroplatinate(II), (CH2NH2(CH2)(2)COOH)(2)[PtCl4]

C8H18Cl4N2O4Pt, monoclinic, P12(1)/n1 (no. 14), a = 8.181(3) angstrom, b = 10.303(5) angstrom, c = 9.073(6) angstrom, beta = 103.2(1)degrees, V = 744.6 angstrom(3), Z = 2, R-gt(F) = 0.080, wR(ref)(F-2) = 0.247, T = 293 K

The effects of chronic administration of cisplatin on oxidative stress in the isolated rat heart [Efekti hronične primene cisplatine na oksidacioni stres izolovanog srca pacova]

Taken into consideration that molecular and cellular mechanisms involved in cardiotoxicity are still not clear the aim of this study was to compare the production of oxidative stress parameters in the isolated rat heart between animals chronically treated with cisplatin and saline. The hearts of male Wistar albino rats (n = 24, 12 per group, age 8 weeks, body mass 250±50 g) were excised and perfused according to the Langendorff technique at gradually increased coronary perfusion pressures (40-120 cmH2O). We followed the production of superoxide anion radicals, hydrogen peroxide, and nitrites and also index of lipid peroxidation during the changes of coronary perfusion pressure (CPP) (from 40 to 120 cm H2O) in coronary venous effluent. Modifications CPP were performed in order to determined if oxidative stress is involved in coronary endothelium response in conditions of hypoxia (lower than 60 cm H2O) and hyperoxia (higher than 80 cm H2O). Based on the results of this research we can conclude that with enhancement of CPP the values of oxidative stress statistically increased. However, this increment is more prominent in control group as a result of preserved endothelium and its more powerful response to hyperoxia. On the other hand, damaged endothelium of cisplatin-treated animals had weaker response to hyperoxia, and also lower antioxidant capacity. © 2018, University of Kragujevac, Faculty of Science. All rights reserved

Potassium 3-dithiocarboxy-3-aza-5-aminopentanoate dihydrate

The synthesis and crystal structure of the title compound, K+. C5H9N2O2S2-. 2H(2)O, are described. The structure consists of potassium cations, 3-dithiocarboxy-3-aza-5-aminopentanoate anions and molecules of water. The anion exists in two tautomeric forms, each described by two resonance structures

N,N′-Bis[2-(methoxycarbonyl)ethyl]ethane-1,2-diammonium dichloride

In the crystal structure of the title compound, C10H22N2O4 2+·2Cl− or (H2Me2eddp)Cl2 (H2Me2eddp2+ is the dimethyl N,N′-di-3-propane­carboxylato­ethane-1,2-diyldiimin­ium cation), the packing is stabilized by an infinite two-dimensional ⋯Cl⋯H—N—H⋯Cl⋯ hydrogen-bonding network. In addition, short C—H⋯Cl contacts are observed

Forest-Stream Linkages: Effects of Terrestrial Invertebrate Input and Light on Diet and Growth of Brown Trout (Salmo trutta) in a Boreal Forest Stream

Subsidies of energy and material from the riparian zone have large impacts on recipient stream habitats. Human-induced changes, such as deforestation, may profoundly affect these pathways. However, the strength of individual factors on stream ecosystems is poorly understood since the factors involved often interact in complex ways. We isolated two of these factors, manipulating the flux of terrestrial input and the intensity of light in a 2×2 factorial design, where we followed the growth and diet of two size-classes of brown trout (Salmo trutta) and the development of periphyton, grazer macroinvertebrates, terrestrial invertebrate inputs, and drift in twelve 20 m long enclosed stream reaches in a five-month-long experiment in a boreal coniferous forest stream. We found that light intensity, which was artificially increased 2.5 times above ambient levels, had an effect on grazer density, but no detectable effect on chlorophyll a biomass. We also found a seasonal effect on the amount of drift and that the reduction of terrestrial prey input, accomplished by covering enclosures with transparent plastic, had a negative impact on the amount of terrestrial invertebrates in the drift. Further, trout growth was strongly seasonal and followed the same pattern as drift biomass, and the reduction of terrestrial prey input had a negative effect on trout growth. Diet analysis was consistent with growth differences, showing that trout in open enclosures consumed relatively more terrestrial prey in summer than trout living in covered enclosures. We also predicted ontogenetic differences in the diet and growth of old and young trout, where we expected old fish to be more affected by the terrestrial prey reduction, but we found little evidence of ontogenetic differences. Overall, our results showed that reduced terrestrial prey inputs, as would be expected from forest harvesting, shaped differences in the growth and diet of the top predator, brown trout

Synthesis and characterization of meridional isomer of uns-cis-(ethylenediamine-N-N'-di-3-propionato)-(S-norleucinato)cobalt(III) semihydrate

The meridional geometrical isomer of uns-cis-(ethylenediamine-N-N'-di-3-propionato)(S-norleucinato)cobalt(III) complex has been prepared by the reaction of sodium uns-cis-(ethylenediamine-N-N'-di-3-propionato)(carbonato)cobaltate(III) with S-norleucine at 75°C. The complex was isolated choromatographically and characterized by elemental analyses, electron absorption and infrared spectroscopy

The preparation and characterization of uns-cis-(ethylene-diamine-N,N'-di-3-propionato)(N-alkylethylenediamines)cobalt(III) complexes

Three octahedral cobalt(III) complexes of the general formula uns-cis-SCo(eddp)(R-en)CClÿ2H2O, where eddp = the tetradentate ONNO-type ligand ethylenediamine-N,N'-di-3-propionate and R-en = a bidentate NN-type ligand, either N-methyl, N-ethyl or N-isopropylethylenediamine. The complexes were prepared by the reaction of sodium uns-cis-(ethylenediamine-N,N'-di-3-propionato)(carbonato)cobaltate(III)dihydrate with the corresponding diamine. They were isolated chromatographically and characterized by elemental analysis, infrared and electronic absorption spectroscopy

The mechanisms of tris(4-morpholinecarbodithioato-S,S′)cobalt(III) complex formation by solid state reaction from ammine cobalt(III) complexes

In this paper, the solid state reaction, conducted with a mixture of pentaamminechlorocobalt(III) chloride and potassium 4-morpholinecarbodithioate was investigated under isothermal conditions. The reaction proceeds at relatively low temperatures (154-192 °C). The yield of product solid-solid reaction, tris(4-morpholinecarbodithioato-S,S')cobalt(III) complex, does not exceed 65%. The kinetic of the reaction of powdered and pressed samples were investigated. The reaction proceeded according to the diffusional mechanism. Activation energies of 200 kJ/mol and 100 kJ/mol for the powdered and pressed form, respectively, were obtained

(ethylenediamine-N,N’-di-3-propionato)(S-arginine)cobalt(III)

Preparation and characterization of facial and meridional isomers of uns-ci

The mechanisms of tris(4-morpholinecarbodithioato-S,S′)cobalt(III) complex formation by solid state reaction from ammine cobalt(III) complexes

In this paper, the solid state reaction, conducted with a mixture of pentaamminechlorocobalt(III) chloride and potassium 4-morpholinecarbodithioate was investigated under isothermal conditions. The reaction proceeds at relatively low temperatures (154-192 °C). The yield of product solid-solid reaction, tris(4-morpholinecarbodithioato-S,S')cobalt(III) complex, does not exceed 65%. The kinetic of the reaction of powdered and pressed samples were investigated. The reaction proceeded according to the diffusional mechanism. Activation energies of 200 kJ/mol and 100 kJ/mol for the powdered and pressed form, respectively, were obtained