789 research outputs found

    The Results Are In! Updated Alternative I-O Graduate Program Rankings

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    In the summer of 2016, we issued a Call for Proposals to submit unique and innovative methodologies to rank I-O graduate programs. In response to this, many projects were proposed to us. After much hard work (and the broader SIOP community’s help), the five selected projects have been completed. Each of these five papers are included in the current issue of TIP. We believe each of these papers will be an important contribution to our field and will guide individuals in the future – as well as generate much thought and discussion about the state of our field and the programs that educate the future of IO Psychology. In particular, we hope that these rankings will result in graduate programs examining them-selves and thinking about ways they excel, as well as areas they could improve. Additionally, we hope that future undergraduate students applying to I-O programs will use these rankings, not to determine what the “best” programs are, but which programs are the best fit for them

    I-O Graduate Program Rankings: Update

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    In the summer 2016 issue of TIP (Salter et al., 2016), we put out a Call for Proposals for updated I-O graduate program rankings. In this call, we were looking for new and unique methodologies for ranking I-O graduate programs that reflect the diversity of values and strengths across our field. We are pleased to announce we have conditionally accepted five proposals. Each of these teams will now conduct their project (which we hope all SIOP members will help with once data collection begins); we anticipate the final rankings will be published in the summer 2018 issue of TIP. Please note that the goal of this project is to make our methodologies public before data collection to reduce the likelihood of researcher degrees of freedom influencing the results. Although frequently unintentional, it is all too common for analytic decisions to be driven in part by the results that follow. Our goal is to achieve transparency in the way rankings were conducted and to present multiple methodologies, to aid students and educators in their decision making

    Call for Proposals for I-O Graduate Program Rankings

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    Are you part of an I-O graduate program that is truly excellent, but the typical ranking systems do not necessarily show that? Would you like to help I-O psychologists (current as well as those who will be entering our field in the future) develop a better understanding of the different strengths of various graduate programs? We are issuing a Call for Proposals for rankings of I-O graduate programs. This is an excellent opportunity for graduate programs to highlight the ways in which they excel, and for individual SIOP members to help contribute to our field. In this Call for Proposals, we are seeking proposals for new and unique methodologies for ranking I-O PhD and MA/MS programs that reflect the diversity of values and strengths across the field of I-O. Multiple ranking methodology submissions will be accepted for publication, resulting in multiple rankings featured in an upcoming issue of TIP. We have developed this call in consultation with the TIP editor, in response to a need for more comprehensive and updated information about graduate programs

    The Analyzing Power for p-p Scattering at 180 MeV

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    This research was sponsored by the National Science Foundation Grant NSF PHY 87-1440

    Gentamicin pharmacokinetics and pharmacodynamics during short-daily hemodialysis

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    BACKGROUND/AIMS: Gentamicin pharmacokinetics have not been described in patients undergoing short-daily hemodialysis (SDHD). The aim of this study is to describe gentamicin pharmacokinetics and dialytic clearance (Cl(dial)) in SDHD patients and simulate gentamicin exposure after six dosing regimens to help guide future dosing. METHODS: Six anuric patients undergoing SDHD were enrolled. Patients received intravenous infusion of 2 mg/kg gentamicin on day 1 after the first HD session followed by HD sessions on days 2, 3, and 4. Blood samples for determination of gentamicin concentrations were serially collected. Gentamicin pharmacokinetic parameters and Cl(dial) and interindividual variability terms (IIV) were estimated using NONMEM VII. Influence of patient weight on systemic clearance (Cl(s)) and central volume of distribution (V(c)) and influence of urea removal estimates on Cl(dial) were assessed. The model was used to simulate gentamicin concentrations after six dosing regimens including pre- and postdialysis as well as daily and every-other-day dosing. RESULTS: A two-compartment model with first-order elimination from central compartment described gentamicin pharmacokinetics. Population estimates for Cl(s) and Cl(dial) were 7.6 and 134 ml/min, respectively. Patient weight was statistically significantly associated with Cl(s) and V(c). Predialysis every-other-day regimens were as effective (C(max) ≥8 mg/l and AUC(48 h) ≥140 mg·h/l) and less toxic (C(min) <2 mg/l and AUC(48 h) <240 mg·h/l) than postdialysis regimens. CONCLUSIONS: Estimated gentamicin Cl(dial) is higher than previous estimates with thrice-weekly regimens. Predialysis every-other-day dosing may be recommended during SDHD

    A Calibration of the K600 FPP from 120 to 200 MeV

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    This research was sponsored by the National Science Foundation Grant NSF PHY-931478

    Quality of Life with Late-Onset Pompe Disease: Qualitative Interviews and General Public Utility Estimation in the United Kingdom

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    Background: Late-onset Pompe disease (LOPD) is a rare, progressive neuromuscular condition typically characterized by weakness of skeletal muscles, including those involved in respiration and diaphragmatic dysfunction. Individuals with LOPD typically eventually require mobility and/or ventilatory support. / Objectives: This study aimed to develop health state vignettes and estimate health state utility values for LOPD in the United Kingdom. / Methods: Vignettes were developed for 7 health states of LOPD with states defined in terms of mobility and/or ventilatory support. Vignettes were drafted based on patient-reported outcome data from the Phase 3 PROPEL trial (NCT03729362) and supplemented by a literature review. Qualitative interviews with individuals living with LOPD and clinical experts were conducted to explore the health-related quality-of-life (HRQoL) impact of LOPD and to review the draft vignettes. Vignettes were finalized following a second round of interviews with individuals living with LOPD and used in health state valuation exercises with people of the UK population. Participants rated the health states using the EQ-5D-5L, visual analog scale, and time trade-off interviews. / Results: Twelve individuals living with LOPD and 2 clinical experts were interviewed. Following the interviews, 4 new statements were added regarding dependence on others, bladder control problems, balance issues/fear of falling, and frustration. One hundred interviews with a representative UK population sample were completed. Mean time trade-off utilities ranged from 0.754 (SD = 0.31) (no support) to 0.132 (SD = 0.50) (invasive ventilatory and mobility support-dependent). Similarly, EQ- 5D-5L utilities ranged from 0.608 (SD = 0.12) to -0.078 (SD = 0.22). / Discussion: The utilities obtained in the study are consistent with utilities reported in the literature (0.670-0.853 for nonsupport state). The vignette content was based on robust quantitative and qualitative evidence and captured the main HRQoL impacts of LOPD. The general public rated the health states consistently lower with increasing disease progression. There was greater uncertainty around utility estimates for the severe states, suggesting that participants found it harder to rate them. / Conclusion: This study provides utility estimates for LOPD that can be used in economic modeling of treatments for LOPD. Our findings highlight the high disease burden of LOPD and reinforce the societal value of slowing disease progression

    A Complete Set of In-plane Spin-transfer Coefficients for Small Angle pp Elastic Scattering at 200 MeV

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    This research was sponsored by the National Science Foundation Grant NSF PHY-931478

    A Coincidence Measurement of D_NN' for p+p Elastic Scattering at T_p = 200 MeV

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    This research was sponsored by the National Science Foundation Grant NSF PHY-931478
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