58 research outputs found
Cryogenic and Magnetic Fracture Mechanics for Structural Integrity Assessment of Large Scale Superconducting Magnets
Endocrinologic, neurologic, and visual morbidity after treatment for craniopharyngioma
Craniopharyngiomas are locally aggressive tumors which typically are focused in the sellar and suprasellar region near a number of critical neural and vascular structures mediating endocrinologic, behavioral, and visual functions. The present study aims to summarize and compare the published literature regarding morbidity resulting from treatment of craniopharyngioma. We performed a comprehensive search of the published English language literature to identify studies publishing outcome data of patients undergoing surgery for craniopharyngioma. Comparisons of the rates of endocrine, vascular, neurological, and visual complications were performed using Pearsonâs chi-squared test, and covariates of interest were fitted into a multivariate logistic regression model. In our data set, 540 patients underwent surgical resection of their tumor. 138 patients received biopsy alone followed by some form of radiotherapy. Mean overall follow-up for all patients in these studies was 54 ± 1.8 months. The overall rate of new endocrinopathy for all patients undergoing surgical resection of their mass was 37% (95% CI = 33â41). Patients receiving GTR had over 2.5 times the rate of developing at least one endocrinopathy compared to patients receiving STR alone or STR + XRT (52 vs. 19 vs. 20%, Ï2P < 0.00001). On multivariate analysis, GTR conferred a significant increase in the risk of endocrinopathy compared to STR + XRT (OR = 3.45, 95% CI = 2.05â5.81, P < 0.00001), after controlling for study size and the presence of significant hypothalamic involvement. There was a statistical trend towards worse visual outcomes in patients receiving XRT after STR compared to GTR or STR alone (GTR = 3.5% vs. STR 2.1% vs. STR + XRT 6.4%, P = 0.11). Given the difficulty in obtaining class 1 data regarding the treatment of this tumor, this study can serve as an estimate of expected outcomes for these patients, and guide decision making until these data are available
Bacterial communities and metabolic activity of faecal cultures from equol producer and non-producer menopausal women under treatment with soy isoflavones
AUTOMATION OF INTERNAL FRICTION MEASUREMENT APPARATUS OF INVERTED TORSION PENDULUM TYPE
The design of an automated internal friction apparatus of inverted torsion pendulum type is described. The wave-form analysis, instead of the traditional wave-height analysis, was employed. In addition to the omission of manual operation or supervision, the accuracy of measurement was increased so much, because, through Fourier transformation of the wave form of a damped oscillation, the disturbing components of parasitic motions such as lateral or precessional one of the pendulum are separated out from the genuine torsional motion and eliminated on calculating the decay constant
Presence of UDP-d-Xylose:beta-D-Glucoside alpha-1,3-D-Xylosyltransferase Involved in the Biosynthesis of the Xylalphal-3Glcbeta-Ser Structure of Glycoproteins in the Human Hepatoma Cell Line HepG2
Cryogenic and Magnetic Fracture Mechanics for Structural Integrity Assessment of Large Scale Superconducting Magnets
Nonomuraea sp. ID06-A0189 inulin fructotransferase (DFA III-forming): gene cloning, characterization and conservation among other Nonomuraea species
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