SOAR 89: Space Station. Space suit test program

The elements of the test program for the space suit to be used on Space Station Freedom are noted in viewgraph form. Information is given on evaluation objectives, zero gravity evaluation, mobility evaluation, extravehicular activity task evaluation, and shoulder joint evaluation

Extravehicular activity system

Viewgraphs and discussion on the extravehicular activity system for space station evolution are presented. The following topics are addressed: (1) EVAS program status; (2) definition of EVAS baseline; (3) baseline functional requirements; (4) definition of evolutionary EVAS; (5) evolutionary EVAS functional requirements; and (6) technology status

Space Station EVA System Evolution Study

Evaluation of Space Station Freedom support of manned exploration is in progress to identify SSF EVA system evolution requirements and capabilities. The output from these studies will provide data to support the preliminary design process to ensure that Space Station EVA system requirements for future missions (including the Transportation Node) are adequately considered and reflected. The study considers SSF support of future missions and the EVA system baseline to determine adequacy of EVA requirements and capabilities, and to identify additional requirements, capabilities, and necessary technology upgrades. EVA demands levied by formal requirements and indicated by evolution mission scenarios are high for the out-years of Space Station Freedom. An EVA system designed to meet the baseline requirements can easily evolve to meet evolution demands with few exceptions. Results to date indicate that upgrades or modifications to the EVA system may be necessary to meet all forseeable hangar induced EVA environments. Work continues to quantity the EVA capability in this regard. Evolution mission scenarios with EVA in and around unshielded nuclear propulsion engines are inconsistent with anthropomorphic EVA capabilities

Extravehicular Activity System Sizing Analysis Tool (EVAS_SAT)

An effort was initiated by NASA/JSC in 2001 to develop an Extravehicular Activity System Sizing Analysis Tool (EVAS_SAT) for the sizing of Extravehicular Activity System (EVAS) architecture and studies. Its intent was to support space suit development efforts and to aid in conceptual designs for future human exploration missions. Its basis was the Life Support Options Performance Program (LSOPP), a spacesuit and portable life support system (PLSS) sizing program developed for NASA/JSC circa 1990. EVAS_SAT estimates the mass, power, and volume characteristics for user-defined EVAS architectures, including Suit Systems, Airlock Systems, Tools and Translation Aids, and Vehicle Support equipment. The tool has undergone annual changes and has been updated as new data have become available. Certain sizing algorithms have been developed based on industry standards, while others are based on the LSOPP sizing routines. The sizing algorithms used by EVAS_SAT are preliminary. Because EVAS_SAT was designed for use by members of the EVA community, subsystem familiarity on the part of the intended user group and in the analysis of results is assumed. The current EVAS_SAT is operated within Microsoft Excel 2003 using a Visual Basic interface system

Chromosomal segregation analysis and HOST-based sperm selection in a complex reciprocal translocation carrier

International audienceIntroduction: Complex chromosomal rearrangements (CCRs) involve two or more chromosomes and at least three breakpoints. Due to their complexity, they are associated with a high number of unbalanced gametes, whose fertilization is often incompatible with viable fetal development. Preimplantation genetic diagnosis (PGD) is usually offered to those patients and typically shows modest results considering the high number of unbalanced embryos. We previously showed that a sperm selection process using the hypo-osmotic swelling test (HOST) allows for an 83% reduction in the proportion of unbalanced spermatozoa (US) in male rearrangements carriers. This is the first report of the use of this procedure in a CCR carrier.Case description: We report on the case of a 36-year-old male t(4;7;14)(q12;p21;q11.2) carrier who presented to our center for infertility. Sperm fluorescent in situ hybridization showed an 88% proportion of unbalanced spermatozoa. After hypo-osmotic incubation and selection of spermatozoa with a specific flagellar conformation, the proportion of unbalanced spermatozoa dropped to 15%.Discussion: In the present case, we show that it is possible to select chromosomally balanced prior to in vitro fertilization in male CCR carriers. This technique has the potential of increasing the proportion of euploid embryos and therefore the chances of healthy pregnancy and birth