536 research outputs found

    Nuevo ensayo para la determinación de frecuencias fundamentales longitudinales, transversales y torsionales en probetas de hormigón

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    For twenty-five years The ASTM method used to determine reductions in concrete durability after freeze-thaw cycling has been C215-60. In this test the fundamental frequencies of a concrete specimen are compared. This test is time consuming, noisy and often inaccurate. In this paper a new method is proposed for measuring the fundamental frequencies of concrete to a single tap via a Fast Fourier Transform. The new test is faster, simpler and more accurate.El método usado por la ASTM desde hace 25 años para la determinación de la durabilidad del hormigón después de sufrir ciclos hielo/deshielo ha sido el C215-60. En este ensayo se comparan las frecuencias fundamentales de una probeta de hormigón. Este ensayo es ruidoso, lleva bastante tiempo y es bastante impreciso. En este trabajo se pone un nuevo método para medias frecuencias fundamentales en el hormigón por simple golpe mediante la TRANSFORMADA RÁPIDA de FOURIER. El nuevo método es más rápido, más simple y más preciso

    Exploring the optimal allostatic load scoring method in women of reproductive age

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    AimsThe aim of this study was to determine the optimal allostatic load scoring method.DesignThis is a secondary analysis of data on women of reproductive age from the 2001-2006 National Health and Nutrition Examination Survey.MethodsWe created allostatic load summary scores using five scoring methods including the count-based, Z-Score, logistic regression, factor analysis and grade of membership methods. Then, we examined the predictive performance of each allostatic load summary measure in relation to three outcomes: general health status, diabetes and hypertension.ResultsWe found that the allostatic load summary measure by the logistic regression method had the highest predictive validity with respect to the three outcomes. The logistic regression method performed significantly better than the count-based and grade of membership methods for predicting diabetes as well as performed significantly better for predicting hypertension than all of the other methods. But the five scoring methods performed similarly for predicting poor health status.ConclusionWe recommended the logistic regression method when the outcome information is available, otherwise the frequently used simpler count-based method may be a good alternative.ImpactThe study compared different scoring methods and made recommendations for the optimal scoring approach. We found that allostatic load summary measure by the logistic regression method had the strongest predictive validity with respect to general health status, diabetes and hypertension. The study may provide empirical evidence for future research to use the recommended scoring approach to score allostatic load. The allostatic load index may serve as an -early warning- indicator for health risk.ç ®ç è¿ é¡¹ç  ç©¶ç ç ®ç å ¨äº ,ç¡®å® æ ä½³é åº è´ è ·è¯ å æ ¹æ³ ã è®¾è®¡è¿ æ ¯å¯¹2001å¹´è ³2006æ é ´å ¨å ½å ¥åº·å è ¥å »æ£ æ ¥è° æ ¥ä¸­è ²é¾ å¦ å¥³æ °æ ®ç äº æ¬¡å æ ã æ ¹æ³ æ ä»¬ä½¿ç ¨äº äº ç§ è¯ å æ ¹æ³ (å æ ¬å ºäº è®¡æ °æ³ ã Z计å æ³ ã é »è¾ å å½ æ³ ã å  å­ å æ æ³ å é ¶å± åº¦æ ¹æ³ )æ ¥å å»ºäº é åº è´ è ·æ± æ »å æ °ã ç ¶å ,æ ä»¬æ£ æ ¥äº ä¸ ä¸ ä¸ªç» æ ç ¸å ³ç å ç§ é åº è´ è ·æ± æ »æ °å ¼ç é¢ æµ æ §è ½:æ ´ä½ å ¥åº·ç ¶æ ã ç³ å°¿ç å é« è¡ å ã ç» æ æ 们å ç °,é »è¾ å å½ æ³ ç é åº è´ è ·æ± æ »å æ °å¯¹è¿ ä¸ ä¸ªç» æ å ·æ æ é« ç é¢ æµ æ 度ã é »è¾ å å½ æ³ å ¨é¢ æµ ç³ å°¿ç æ ¹é ¢ç è¡¨ç °æ æ ¾ä¼ äº å ºäº è®¡æ °æ³ å é ¶å± åº¦æ ¹æ³ ,å ¨é¢ æµ é« è¡ å æ ¹é ¢ç è¡¨ç °ä¹ æ æ ¾ä¼ äº æ æ å ¶ä» æ ¹æ³ ã ä½ è¿ äº ç§ è¯ å æ ¹æ³ å ¨é¢ æµ ä¸ è ¯å ¥åº·ç ¶æ æ ¹é ¢ç è¡¨ç °ç ¸ä¼¼ã ç» è®ºå½ ç» æ èµ æ å ¯ç ¨æ ¶,æ ä»¬æ ¨è é »è¾ å å½ æ³ ,å ¨å ¶ä» æ ¹é ¢,å¸¸ç ¨ä¸ æ ´ç® å ç å ºäº è®¡æ °æ³ å ¯è ½ä¹ æ ¯ä¸ ä¸ªä¸ é ç é æ ©ã å½±å è¯¥ç  ç©¶æ¯ è¾ äº ä¸ å ç è¯ å æ ¹æ³ ,并æ å ºäº æ ä½³è¯ å æ ¹æ³ ç 建议ã æ 们å ç °ç ¨é »è¾ å å½ æ³ è¿ è¡ ç é åº è´ è ·æ± æ »å æ °å¯¹æ ´ä½ å ¥åº·ç ¶æ ã ç³ å°¿ç å é« è¡ å å ·æ æ 强ç é¢ æµ æ æ æ §ã è¯¥ç  ç©¶å ¯ä»¥ä¸ºä» å ä½¿ç ¨æ ¨è ç è¯ å æ ¹æ³ å¯¹æ æ é åº è´ è ·è¯ å æ ä¾ å® éª æ §è¯ æ ®ã é åº è´ è ·æ æ °å ¯ä»¥ä½ ä¸ºå ¥åº·é£ é ©ç -é¢ è­¦-æ æ  ãPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/151983/1/jan14014_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/151983/2/jan14014.pd

    Soils of Tropical Dry Forest and with Different Crops Presenting Ascospores of Monosporascus cannonballus

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    The vine decline caused by Monosporascus cannonballus is a limiting factor in different crops in several countries. The objective of this study was to quantify the M. cannonballus ascospores in soils covered with tropical dry forest and areas cultivated with pineapple, cotton, coconut, corn, mango, melon, papaya, sorghum and watermelon. Five areas were sampled in tropical dry forest and every crop. The M. cannonballus ascospores were extracted using the flotation method of sucrose. Ascospores of M. cannonballus were detected in all soil samples from Rio Grande do Norte and Ceará states, including tropical dry forest. There were significant differences among the ascospores densities of M. cannonballus, which varied from 0.55 to 2.21 ascospores g-1 soil. The lower densities were found in areas with cotton, coconut, mango, pineapple, and melon within the first and fifth years of cultivation, in addition to uncultivated areas of tropical dry forest. The highest ascospores density was found in papaya areas. Up to date, there is no study to prove that this crop is considered host of this phytopathogen. Cultivated areas with cucurbitaceous with more years of cultivation presented higher densities of M. cannonballus ascospores in soils from Brazilian semiarid. However, there is no direct relationship between M. cannonballus population density in the soil and the susceptibility of the host being cultivated in the soil at the time of sampling

    Naloxone Prolongs Abdominal Constriction Writhing-Like Behavior in a Zebrafish-Based Pain Model

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    The ability to detect noxious stimuli is essential to survival. However, pathological pain is maladaptive and severely debilitating. Endogenous and exogenous opioids modulate pain responses via opioid receptors, reducing pain sensibility. Due to the high genetic and physiological similarities to rodents and humans, the zebrafish is a valuable tool to assess pain responses and the underlying mechanisms involved in nociception. Although morphine attenuates pain-like responses of zebrafish, there are no data showing if the antagonism of opioid receptors prolongs pain duration in the absence of an exogenous opioid. Here, we investigated whether a common opioid antagonist naloxone affects the abdominal constriction writhing-like response, recently characterized as a zebrafish-based pain behavior. Animals were injected intraperitoneally with acetic acid (5.0%), naloxone (1.25 mg/kg; 2.5 mg/kg; 5.0 mg/kg) or acetic acid with naloxone to investigate the changes in their body curvature for 1 h. Acetic acid elicited a robust pain-like response in zebrafish, as assessed by aberrant abdominal body curvature, while no effects were observed following PBS injection. Although naloxone alone did not alter the frequency and duration of this behavior, it dose-dependently prolonged acetic acid-induced abdominal curvature response. Besides reinforcing the use of the abdominal writhing-like phenotype as a behavioral endpoint to measure acute pain responses in zebrafish models, our novel data suggest a putative role of endogenous opioids in modulating the recovery from pain stimulation in zebrafish. © 2019 Elsevier B.V.We recognize the financial support and fellowships from Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (FAPERGS), and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) . F.V.C. was recipient of CAPES fellowship. J.C. and F.V.S. receive the CNPq fellowship. D.B.R. is a recipient of CNPq research productivity grant ( 305051/2018-0 ) and his work is also supported by the PROEX/CAPES (process number 23038.005848/2018-31) and PRONEM/FAPERGS (process number 16/2551-0000248-7) fellowship grants. A.V.K. is the Chair of the International Zebrafish Neuroscience Research Consortium (ZNRC). His research is supported by the Russian Science Foundation (RSF) grant 19-15-00053. All authors contributed to the preparation of the manuscript and approved its final version. The funders had no influence on the study design, collection, analysis, and interpretation of data, as well as on writing and submission of this manuscript
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