El personal directivo público: una ampliación del ámbito subjetivo del Real Decreto 1382/1985

La regulación del personal directivo de los Organismos públicos ha dado un giro con la posibilidad de aplicación del régimen jurídico-laboral. De forma fue la Ley 7/2007, de 12 de abril, del Estatuto Básico del Empleado público, ha abierto la puerta, en un espacio tan hermético como el sector público institucional, a la entrada de una figura propia del ámbito empresarial, como es la del alto directivo laboral regulado por el Real Decreto 1382/1985. Sin embargo, la aplicación del régimen jurídico laboral en el ámbito público plantea no pocos problemas, de los que el más relevante es la delimitación con otras figuras jurídicas con las que limita por arriba y por abajo; y al que se añade la indemnización por cese o, en su caso, por despido

A game-based approach to the teaching of object-oriented programming languages

Students often have difficulties when trying to understand the concepts of object-oriented programming (OOP). This paper presents a contribution to the teaching of OOP languages through a game-oriented approach based on the interaction with tangible user interfaces (TUIs). The use of a specific type of commercial distributed TUI (Sifteo cubes), in which several small physical devices have sensing, wireless communication and user-directed output capabilities, is applied to the teaching of the C# programming language, since the operation of these devices can be controlled by user programs written in C#. For our experiment, we selected a sample of students with a sufficient knowledge about procedural programming, which was divided into two groups: The first one had a standard introductory C# course, whereas the second one had an experimental C# course that included, in addition to the contents of the previous one, two demonstration programs that illustrated some OOP basic concepts using the TUI features. Finally, both groups completed two tests: a multiple-choice exam for evaluating the acquisition of basic OOP concepts and a C# programming exercise. The analysis of the results from the tests indicates that the group of students that attended the course including the TUI demos showed a higher interest level (i.e. they felt more motivated) during the course exposition than the one that attended the standard introductory C# course. Furthermore, the students from the experimental group achieved an overall better mark. Therefore, we can conclude that the technological contribution of Sifteo cubes – used as a distributed TUI by which OOP basic concepts are represented in a tangible and a visible way – to the teaching of the C# language has a positive influence on the learning of this language and such basic concepts

Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimer´s disease and type two diabetes

Background: While aging is the main risk factor for Alzheimer´s disease (AD), emerging evidence suggests that metabolic alterations such as type 2 diabetes (T2D) are also major contributors. Indeed, several studies have described a close relationship between AD and T2D with clinical evidence showing that both diseases coexist. A hallmark pathological event in AD is amyloid-β (Aβ) deposition in the brain as either amyloid plaques or around leptomeningeal and cortical arterioles, thus constituting cerebral amyloid angiopathy (CAA). CAA is observed in 85–95% of autopsy cases with AD and it contributes to AD pathology by limiting perivascular drainage of Aβ. Methods: To further explore these alterations when AD and T2D coexist, we have used in vivo multiphoton microscopy to analyze over time the Aβ deposition in the form of plaques and CAA in a relevant model of AD (APPswe/ PS1dE9) combined with T2D (db/db). We have simultaneously assessed the effects of high-fat diet-induced prediabetes in AD mice. Since both plaques and CAA are implicated in oxidative-stress mediated vascular damage in the brain, as well as in the activation of matrix metalloproteinases (MMP), we have also analyzed oxidative stress by Amplex Red oxidation, MMP activity by DQ ™ Gelatin, and vascular functionality. Results: We found that prediabetes accelerates amyloid plaque and CAA deposition, suggesting that initial metabolic alterations may directly affect AD pathology. T2D significantly affects vascular pathology and CAA deposition, which is increased in AD-T2D mice, suggesting that T2D favors vascular accumulation of Aβ. Moreover, T2D synergistically contributes to increase CAA mediated oxidative stress and MMP activation, affecting red blood cell velocity. Conclusions: Our data support the cross-talk between metabolic disease and Aβ deposition that affects vascular integrity, ultimately contributing to AD pathology and related functional changes in the brain microvasculature.University of Cadiz Predoctoral FellowshipEuropean CommissionEuropean Commission Joint Research Centre GA 847749Programa Estatal de Generacion de Conocimiento y Fortalecimiento Cientifico y Tecnologico del Sistema de I + D + i y del Programa Estatal de I + D +i Orientada a los Retos de la Sociedad, del Plan Estatal de Investigacion Cientifica y Tecnica y de Innovaci PID2020-115499RB-I00/AEIAgencia Estatal de Investigacion (AEI) BFU 2016-75038-REuropean CommissionSpanish Government Spanish GovernmentAndalucia se mueve con Europa P20-0092

Cinema and Fashion in Hollywod: The Forties and The Fifties

El artículo que tienen en sus manos es la continuación de una serie iniciada en el número anterior de esta revista, en la cual tratamos de ofrecer una visión general de la relación entre el mundo del cine y la moda. La serie continúa, analizando las décadas de los cuarenta y cincuenta. La primera estuvo directamente influenciada por las restricciones impuestas debido a la II Guerra Mundial. La segunda fue una época de prosperidad económica que permitió que la historia del cine y la moda alcanzaran niveles de influencia en la sociedad que no ha vuelto a tener desde entonces. Esperamos abordar las próximas décadas, hasta la actualidad, en un artículo posterior que será el último de esta serie.This article continues a series, initiated in the previous number of this journal, where we’ve tried offer a general view in the relation between cinema and fashion. The series follows analyzing the forties and fifties. The first one was directly influenced by the restricton imposed during World War II. The second was a period of economic prosperity and where the influence of fashion on cinema and society reached a high point that has not returned since them. We expect to approach the following decades up to the current times in a later article that will be the last one of this serie

Cinema and fashion. From the beginning to the thirties

La relación entre el cine y la moda es casi tan antigua como el primero. Sin embargo, este tema ha sido escasamente tratado en la bibliografía en español. En este artículo, que se inicia con una introducción sobre las principales teorías de la moda, pretendemos ofrecer al lector una visión general acerca de la relación del cine con la moda, desde sus inicios en la década de los diez, pasando por la Era del Jazz, hasta culminar en el glamoroso Hollywood de la década de los treinta. Debido a la falta de espacio, y a la complejidad del tema, hemos decidido finalizar en este período, aunque esperamos poder analizar las décadas siguientes en un artículo posterior.The relation between cinema and fashion is as old as the cinema birth. However, this topic has not been sufficiently studied by the Spanish bibliography. In this paper, which starts with a short introduction about the main fashion theories, we want to show to the reader a comprehensive vision about this particular relation, since the beginning in the 1910s, through the Jazz Era, finishing at the glamorous Hollywood golden age, in the 1930s. Due to we don’t have space enough in this journal and, on the other hand it is a complex and deep topic too, we have decided to finish in this period of time although we are looking forward to analyzing the following decades in a forthcoming paper