13 research outputs found

    Heart Beat Monitoring And Wireless Data Logging Using Arm Cortex A8

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    Increasing importance in monitoring and logging the real time patient’s related data has led to the development of a new wireless data acquisition system. The basic concept presented in this paper is that we have made one type of wireless data logger[1] system using arm platform which is logging the real time heartbeat[2] data in one text file it is give the heartbeat rate with respect to time. Here we use UDOO[8] development board, UDOO is a single-board computer development platform that merges a dual or quad core ARM Free scale Cortex-A9 i.MX.6 CPU and an Arduino[4] compatible board embedded with a dedicated ARM Atmel SAM3X8E CPU. Physical data is converted in to the electrical form using Arduino UNO R3 and after processing these data it will be transmitted by the RFM. Same way at receiver side one RFM device is required to receive the data which was transmitted by the transmitter. Once the data is received, these data will be given to UDOO board. In UDOO board the data is processed and the data will be monitored on LCD or DVI Monitor

    Effects of Usnic Acid on Hyperglycemia and Renal Function in Streptozotocin-Induced Diabetic Rats

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    Background: Diabetic hyperglycemia and glomerular hyper filtration play a causative role in the progression of chronic kidney disease. Renal glucose handling via Sodium-Glucose Cotransporter (SGLT)-2 is a targetable approach and SGLT-2 inhibitors have proven therapeutic benefits in diabetic kidney disease. Usnic Acid (UA) is an active constituent of lichen species and symbiotic organism of algae and fungi, which is variously studied in folk medicine. The objective of this study was to demonstrate the beneficial effects of UA on glucose homeostasis and renal function in streptozotocin-induced diabetic Sprague-Dawley rats and to determine whether UA has an effect on regulation of SGLT that may further aid in glucoregulation and renal function. Methods: Type 1 diabetes was induced in Sprague-Dawley rats with Streptozotocin (STZ, 60mg/kg) by intraperitoneal route on day 0. Diabetic rats were treated with UA (75 mg/kg) from day 15 to 35 via oral gavage. On day 35, urine was collected and Oral Glucose Tolerance Test (OGTT) was performed. After OGTT, blood was collected through cardiac puncture and kidneys were preserved for biochemical analysis. The results are expressed as mean ± standard error of the mean for n=8 rats per study group. The data were subjected to 1-way or 2-way ANOVA with Bonferroni’s multiple comparison post hoc test using Graph Pad Prism 5 and were considered significant at p≤0.05. Results: Diabetic rats chronically treated with UA had improved hyperphagia, hyperglycemia and glucose intolerance, glomerular hyper filtration, and urinary protein excretion (p\u3c0.05). However, UA did not prevent loss of circulating insulin in diabetic rats. UA’s blood glucose lowering effect was associated with enhanced diuretic-glucosuric response and decreased protein expression of renal SGLT-1 (p\u3c0.05). While protein expression of SGLT-2 was partially increased in the diabetic kidney and it was not decreased by UA. Metabolic corrections with UA treatment occurred in parallel with reductions in uremia and improvement of renal function indices. Additionally, in diabetic rat kidney, UA treatment corrected oxidative changes. Conclusions: Based on preliminary findings we conclude that chronic treatment of UA may act in an insulin-independent manner in lowering of diabetic hyperglycemia and improvement of renal function

    Diuretic, Glucosuric and Natriuretic Effect of Pantoyltaurine in Diabetic Sprague-Dawley Rats

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    Sodium-glucose co-transporter (SGLT) inhibitors offer a novel tool to control hyperglycemia and its complications. We present preliminary findings of pantoyltaurine, N-substituted analog of taurine, as diuretic, glucosuric and natriuretic agent in streptozotocin (60 mg/kg/mL, i.p.)-induced type 1 diabetic Sprague-Dawley rats and whether pantoyltaurine has an effect on regulation of SGLT isoforms that may further help in reducing hyperglycemia and improving renal function. After 14 days of persistent diabetes, phlorizin (0.4 g/kg/day, s.c.) or pantoyltaurine (2.4 mM/kg/day, p.o.) was administered for three weeks, days 15 - 35. As expected, diabetic rats showed persistent hyperglycemia, hyperphagia and weight loss. Pantoyltaurine and phlorizin-treated diabetic rats consumed less diet, showed significant weight loss, reduced persistent hyperglycemia as well as reduced glucose load after oral glucose tolerance test. Diuretic, glucosuric and natriuretic response of diabetic rats was enhanced by pantoyltaurine independent of renal and plasma oxidative stress, plasma insulin and renal expression of SGLT-2. Phlorizin and pantoyltaurine reduced renal expression of SGLT-1, which accounts for ≤ 10% of glucose reabsorption. However, pantoyltaurine, but not phlorizin, normalized elevated fractional excretion of urea nitrogen and clearance of blood urea nitrogen in diabetic rats, suggesting lessening effect of pantoyltaurine on uremic toxicity associated with diabetes. Collectively, our preliminary findings show that chronic treatment with pantoyltaurine may help in an insulin-independent manner to lower diabetic hyperglycemia by producing diuresis, glucosuria and natriuresis that may have translated in improvement of renal function

    “A STUDY TO ASSESS RELATIONSHIP BETWEEN BACK PAIN AND BODY POSTURE AMONG PRIMI ANTENATAL MOTHER DURING THIRD TRIMESTER IN SELECTED HOSPITALS NADIAD”

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    any females experience back pain during pregnancy. The causes are manifold: their weight increase on the one hand, and the specific physiology of the spine on the other. During pregnancy, a woman’s body weight increases by 15 to 25 percent; this signifies a greater burden on the tendons, ligaments, and joints1. Furthermore, relaxin and estrogen loosen the ligaments and thus create an additional predisposition for, injury23. The enlarged uterus and the increase in breast volume shift the body’s center of gravity to the front. The pelvis is tilted simultaneously and lumbar lordosis increases1. Material and Methods:The study is Quantitative non experimental in the nature. research approach through  research design descriptive co-relational study was adopted. Non-probability convenient sampling method was used to enrol 50 women residing at Nadiad Maternity Hospital. The data were collected structure questionnaire on Body posture in day to day activities and pain scale.Data analysis was done by  descriptive and inferential statistics. Result: Assessment of Body posture of Primi Third Trimester Antenatal Mother in day to day life activity.Among the 50 Antenatal Mother 07(40%) had ill body posture, 38(78%) had Moderately good body posture, 04(08%) had good body posture .The chi-square is significant and that shows there was an association between back pain & body posture.In order to assess relationship between back pain & body posture, Structured Questionnaire was made consisting 15 questions with 02 options in the form of image.To evaluate back pain of Primi Antenatal Third Trimester Mother we took visual Analog pain scale with 0-10 score.In that 11(22%) woman had low level of pain.39(78%) had moderate level of pain and no any woman had sever pain among that 50 samples. Conclusion: The study concluded that antenatal mothers body posture have positive   relationship with back pain . and level of pain is associated with body posture

    Preservation and Handling Practices of Household Drinking Water in Ahmedabad city with special reference to Bacterial Contamination and Diarrheal Episode in Children: A Cross Sectional Study

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    Background: Safe drinking water is essential for healthy human life. Presence of coliform organism, E. coli in particular, has been found to be the most specific bacteriological indicator of faecal contamination. Studying their preservation and handling practices of household drinking water, its contamination and diarrheal episodes in children is very necessary for hygiene promotion intervention. Methods: This crosssectional study was conducted at urban field practice area of community medicine department B.J.M.C, Ahmedabad in year 2020-2021. Total 168 Drinking water samples were collected from each household and tested at microbiology department. Information regarding household characteristics, preservation and handling practices of drinking water were gathered from mother using pre-tested and pre-designed proforma. Data were entered in Microsoft excel and analysed using Epi-info Software. Result: Out of 168 households studied, 165(98.2%) households used matka / earthen pot and 161(95.8%) used narrow necked covered container to preserve drinking water. Only in 10 (5.8%) households‘ water was filtered with folded cotton cloth at the time of collection. 101 (60%) water containers did have tap while 67 (39.8%) didn‘t have it. 4/168 (2.3%) samples were bacteriologically not acceptable for drinking purpose. Conclusion: Narrow necked coveredmatka (earthen pot) was the most commonly used container to preserve drinking water. Though prevalence of bacterial contamination and ADD episodes in under five child were low due to pre-treated piped water supply, diarrhoeal morbidity is more in household where broad necked, non tapped containers used. Education of mother has positive impact on preservation and handling practices of drinking water

    A novel approach for antibody nanocarriers development through hydrophobic ion-pairing complexation

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    The PDF for the 5/25/78 meeting is 44 pages long and covers topics such as: a resolution for Charles C. Thompson; faculty tenure appointments; 1978-1979 traffic and parking regulations; lease assignment at the Amarillo campus; medallion presentations to Horn Professors Ayoub and Wright; the appointment of directors of the Texas Tech University Foundation; and numerous building projects including the naming of the Wiggins Dining Hall as the J. Williams Davis Athletic Dining Hall, renovation of the old Library for Mathematics, and completion dates for the Food Science-Home Economics Building, the Killgore Beef Cattle Teaching and Research Center, and the new campus Warehouse
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