1,593 research outputs found
Estimation of network externalities and critical mass in the mobile telephone market: a panel data analysis of the OECD countries
Network Externalities, Mobile Telecommunication, Critical Mass
Galectin-1 in myelin repair
Galectin-1 (Gal-1) is a member of a highly conserved family of animal lectins which binds to the common disaccharide [GalÎČ(1-4)-GlcNAc] on both N- and O-glycans decorating cell surface glycoconjugates. Current evidence supports a role for Gal-1 in the pathophysiology of multiple sclerosis (MS), one of the most prevalent chronic inflammatory diseases, as approximately one third of MS patients generate high titres of anti-Gal-1 antibodies. Four different lesion types have been described in MS: pattern-1 and -2 lesions are thought to be mediated by the autoimmune response, while pattern-3 and -4 lesions are considered primary oligodendropathy. The first two types are experimentally simulated in mice by experimental autoimmune encephalomyelitis (EAE), while the second two are mimicked by toxic models such as cuprizone (CPZ) or lysolecithin (LPC) administration. Studies in EAE models have demonstrated that Gal-1 is highly expressed in the acute phase of the disease and that its deficiency leads to severe inflammation-induced neurodegeneration [1]. Regarding its mechanism of action,Fil: Rinaldi, Mariana. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Houssay. Instituto de QuĂmica y FĂsico-QuĂmica BiolĂłgicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y BioquĂmica. Instituto de QuĂmica y FĂsico-QuĂmica BiolĂłgicas; ArgentinaFil: Thomas, Laura. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Houssay. Instituto de QuĂmica y FĂsico-QuĂmica BiolĂłgicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y BioquĂmica. Instituto de QuĂmica y FĂsico-QuĂmica BiolĂłgicas; ArgentinaFil: Pasquini, Laura Andrea. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Houssay. Instituto de QuĂmica y FĂsico-QuĂmica BiolĂłgicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y BioquĂmica. Instituto de QuĂmica y FĂsico-QuĂmica BiolĂłgicas; Argentin
Household debt sustainability: what explains household non-performing loans? An empirical analysis
Sound household financial conditions are relevant for both financial and monetary stability. Therefore, we analyse household financial fragility in a sample of euro area countries with the aim to shed some light on the nature of the large debt increase accumulated in recent years. We focus on household arrears on payment obligations, which are one of the most direct measures of financial stress of the sector. The probability of falling into arrears is derived from a life-cycle type of model and is investigated empirically using a cross-section and time series approach. We analyse cointegration and model arrears within an errorcorrection framework. The results suggest that the financial conditions of households might become more vulnerable to adverse shocks in their income and wealth. JEL Classification: C23, G21, D14default, household debt sustainability, non-performing loans, Panel Cointegration
Toxoplasmosis in livestock in Italy: an epidemiological update
Infection with Toxoplasma gondii is one of the most common parasitic infections of human being
and other warm-blooded animals. It has been found worldwide from Alaska to Australia. Public health
organizations repeatedly encourage the collection of accurate data about T. gondii in animals and humans
due to its medical importance as a major source of parasitic zoonosis. For these reasons, epidemiological
updates on toxoplasmosis in livestock are strongly advised also to plan control strategies. In the present
paper, seroprevalence data on T. gondii that have been recorded in livestock from different Italian regions
over the last 3 decades are reviewed, showing the high level of exposure of livestock to this parasite
Modelling riverbank retreat by combining reach-scale hydraulic models with bank-scale erosion and stability analyses
River morphodynamics and sediment transportBank erosion and protectio
POTENSI PENERAPAN PRODUKSI BERSIH PADA RUMAH POTONG HEWAN (RPH) KOTA JAMBI
Penelitian ini dilakukan untuk menganalisis potensi pencemaran dan pemanfaatan limbah cair dan limbah padat dari UPTD Rumah Potong Hewan (RPH) Kota Jambi, serta penerapan produksi bersih bersih berdasarkan Guidance Manual: How to Establish and Operate Cleaner Production Centres. Parameter yang diambil adalah BOD, COD, TSS, Minyak & Lemak, pH. Limbah padat berupa C dan N, serta wawancara dengan pekerja. Hasil penelitian menunjukan kualitas BOD 11.280 mg/l, COD 17.110 mg/l, TSS 2.300 mg/l, Minyak & Lemak 168 mg/l berada di atas standar baku mutu yang berpotensi mencemari lingkungan kecuali pH 7,9 yang masih dibawah baku mutu. Darah dapat berpotensi sebagai pakan ternak sekitar 60 kg/hari, urine menjadi pupuk organik cair sekitar 900 liter. Limbah padat berpotensi menjadi Pembangkit Listrik Tenaga Biogas (PLTB) sekitar 11,28 kWh/hari dan pupuk organik/kompos yang bisa meningkatkan produktivitas pertanian sekitar 180kg/hari. kesimpulan yang dapat diambil untuk mengoptimalkan produksi bersih, yakni: pemasangan keran, pemasangan water sprayer gun, penggunaan masker, dan pembuatan poster mengenai produksi dengan penghematan mencapai Rp 3.718.578,08/tahun
A microwave-based chemical factory in the lab: From milligram to multigram preparations
Microwave technology is changing the way we design and optimize synthetic protocols and their scaling up to multigram production levels. The latest generation of dedicated microwave reactors enables operators to quickly screen reaction conditions by means of parallel tests and select the best catalyst, solvent, and conditions. Pilot scale synthetic procedures require flow-through conditions in microwave flow reactors which can be obtained by adapting classic batch protocols. Microwave-assisted chemical processes play a pivotal role in the design of sustainable multigram preparations which address the double requirement of process intensification and competitive production costs. Although most researchers are likely to be acquainted with the great potential of dielectric heating, the advantages and disadvantages of a particular device or the conditions needed to maximize efficiency and functionality are often overlooked. The double aims of the present review are to provide a panoramic snapshot of commercially available lab microwave reactors and their features as well as highlighting a few selected applications of microwave chemistry of particular relevance
A model of the card payment system and the interchange fee.
Model; Working;
Beyond the limits of accountants as âtrusted advisorsâ for small and medium sized enterprises:environmental sustainability advice
We present emerging research on the potential of small accounting practices as
advisors on environmental sustainability for their small and medium sized clients
(SMEs). Enabling this resource could have substantial implications to improve
sustainability because SMEs are notoriously difficult to reach and influence, but their
most âtrusted advisorâ is consistently their accountant. Using Habermasâ notion of
steering, we present research data primarily from interviews with accountants which
shows that the personal trust (relational steering mechanism) currently enjoyed is
inadequate to facilitate the provision of sustainability advice by accountants beyond
reflection on their own experiences. There is a lack of institutional trust in the
profession as credible providers of sustainability advice, and individuals lack the
skills and knowledge to offer environmental accounting. Without these, transactional
steering and formalized environmental sustainability advice by small accountants to
SMEs is unlikely to emerge. We conclude with research recommendations and
implications for the accounting professio
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