11 research outputs found
La formación docente en momentos de cambios: ¿Qué nos dicen los profesores principiantes universiatrios?
Este estudio cualitativo con una metodología de estudios de casos múltiple examina la opinión de los profesores principiantes de la Universidad de Barcelona sobre las consecuencias del proceso de implementación del Espacio Europeo de Educación Superior (EEES). Indaga sobre la valoración que realiza el profesorado sobre la formación recibida en el postgrado de 'Iniciación a la docencia universitaria' y sobre los aprendizajes que les generó la experiencia formativa. La muestra de la investigación ha estado constituida por diez profesores principiantes de diferentes ámbitos de conocimiento de la Universidad de Barcelona y los datos proceden de la realización de entrevistas en profundidad. Entre los hallazgos más importantes, cabe destacar su percepción sobre la implementación del EEES y las propuestas que dan sobre los cambios que debería realizar la Universidad para una verdadera reforma de la formación de los docente
Validation of the CT scores in the different cohorts.
<p>Validation of the CT scores in the different cohorts.</p
CT models in multivariable analysis together with available IMPACT variables.
<p>CT models in multivariable analysis together with available IMPACT variables.</p
Patient flow diagram.
<p>Flowchart diagram of the eligible patients and screening process to exclude patients who did not fulfill inclusion criteria. CT, computerized tomography; NICU, neuro-intensive care unit; TBI, traumatic brain surgery.</p
The Finnish and Dutch study samples used in the association analysis of saccular intracranial aneurysm (sIA) disease.
*<p>Unknown familial sIA status for 35 patients.</p>**<p>Number of sIAs not known for 16 patients.</p><p>SD = Standard deviation.</p
The locus with a genome-wide significant association to the number of saccular intracranial aneurysms (sIA) per individual in the Finnish samples.
*<p>For each variant major allele/minor allele, locus and base pair position are given.</p>**<p>Located in the intron of the given gene.</p>§<p>See <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004134#pgen.1004134.s015" target="_blank">Table S9</a> for heterogeneity statistics.</p
Five loci with a genome-wide significant association to saccular intracranial aneurysm (sIA) disease in the Finnish and Dutch samples.
*<p>For each variant minor allele/major allele, locus and base pair position are given.</p>**<p>The variant's distance (kb) to the nearest gene is given.</p>***<p>Located in the intron of the given gene.</p>†<p>The previously reported 9p21.3 locus <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004134#pgen.1004134-Yasuno2" target="_blank">[12]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004134#pgen.1004134-Helgadottir1" target="_blank">[39]</a>.</p>‡<p>The previously studied 2q33.3 locus with inconclusive evidence (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004134#s4" target="_blank">Materials and Methods</a>).</p>§<p>Some heterogeneity in effect sizes exists between cohorts. See <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004134#pgen.1004134.s015" target="_blank">Table S9</a> for heterogeneity statistics.</p
Study design.
<p>The Finnish discovery and replication cohorts represent a population with over two-fold increased risk of subarachnoid hemorrhage from ruptured saccular intracranial aneurysm (sIA-SAH). The Finnish discovery cohort was intentionally enriched with familial sIA patients, and 9.4M genotyped and imputed variants were studied. The loci with p<5E-6 were replicated in an independent and unselected Finnish sIA sample. The allele frequencies and effect sizes of the replicated variants in Finland were finally compared to continental European population using a Dutch sample. The sIA-SAH risk is not increased in the Netherlands (‘general risk’ in the figure).</p