6,459 research outputs found

    Comment on "PT Symmetry as a Generalization of Hermiticity" [arXiv:1002.2676]

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    We notice that the general PT-symmetric Hamiltonian matrix(N=2) having 6-real parameters fails to reproduce one parameter PT-symmetric matrix.Comment: Title unchanged ,one ref [5] added . Abstract changed . All the previous matrices have been changed consideing the ref[5

    NEUROPROTECTIVE EFFECT OF METHANOLIC EXTRACT OF SARGASSUM WIGHTII ON HALOPERIDOL INDUCED CATALEPSY AND TARDIVE DYSKINESIA IN ALBINO RATS

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    Objective: The present study was designed to evaluate the neuroprotective effect of methanolic extract of Sargassum wightii on haloperidol-induced catalepsy and tardive dyskinesia in Wistar albino rats. Methods: In this study, thirty Wistar albino rats were randomly divided into six groups. Gr-I served as control. Haloperidol (1 mg/kg intraperitoneally) was administered to rats of Gr-II to Gr-V for twenty-one consecutive days to induce catalepsy and tardive dyskinesia. Animals of Gr-II to Gr-V were orally administered with vehicle, levodopa carbidopa combination (30 mg/kg), Sargassum extract 200 and 400 mg/kg respectively. All the drugs and vehicles were given orally one hour before haloperidol injection for twenty one consecutive days. The cataleptic scores were recorded using standard bar test. Tardive dyskinesia was assessed in terms of vacuous chewing movement (VCM) and tongue protrusion (TP) scores. After behavioural testing, all animals were sacrificed on twenty-second day and various biochemical parameters like MDA, SOD and GSH were estimated in brain tissue. Results: Chronic administration of haloperidol significantly increased cataleptic scores, VCM and TP scores. (p<0.001) Sargassum wightii extract (400 mg/kg) significantly inhibited haloperidol-induced catalepsy, VCM and TP (p<0.001) Haloperidol increased MDA and decreased SOD and GSH in brain tissue to a highly significant extent (p<0.001) Sargassum extract at 400 mg/kg also significantly reversed the haloperidol-induced alteration in brain oxidative stress markers. Conclusion: Sargassum wightii inhibits haloperidol-induced catalepsy and tardive dyskinesia. Thus it may be used as a unique therapeutic adjunct for the prevention of neuroleptic-induced extrapyramidal symptoms, however, it has to be explored more

    Necessary and sufficient conditions for the oscillation of higher-order differential equations involving distributed delays

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    In this article, we establish necessary and sufficient conditions for the oscillation of both bounded and unbounded solutions of the differential equation \begin{equation} \bigg[x(t)+\int_{0}^{\lambda}p(t,v)x(\tau(t,v))\,\mathrm{d}v\bigg]^{(n)}+\int_{0}^{\lambda}q(t,v)x(\sigma(t,v))\,\mathrm{d}v=\varphi(t)\quad\text{for } t \geq t_{0},\notag \end{equation} where nNn\in\mathbb{N}, t0,λR+t_{0},\lambda\in\mathbb{R}^{+}, pC([t0,)×[0,λ]R)p\in C([t_{0},\infty)\times[0,\lambda] \mathbb{R}), qC([t0,)×[0,λ],R+)q\in C([t_{0},\infty)\times[0,\lambda],\mathbb{R}^{+}), τC([t0,)×[0λ],R)\tau\in C([t_{0},\infty)\times[0 \lambda],\mathbb{R}) with limtinfv[0,λ]τ(t,v)=\lim_{t\to\infty}\inf_{v\in[0,\lambda]}\tau(t,v)=\infty and supv[0,λ]τ(t,v)t\sup_{v\in[0,\lambda]}\tau(t,v)\leq t for all tt0t\geq t_{0}, σC([t0,)×[0,λ],R)\sigma\in C([t_{0},\infty)\times[0,\lambda],\mathbb{R}) with limtinfv[0,λ]σ(t,v)=\lim_{t\to\infty}\inf_{v\in[0,\lambda]}\sigma(t,v)=\infty, and φC([t0,),R)\varphi\in C([t_{0},\infty),\mathbb{R}). We also give illustrating examples to show the applicability of these results

    A THREE-DIMENSIONAL ANALYSIS OF MALE AND FEMALE ELITE SPRINT KAYAK PADDLERS

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    The purpose of this study was to investigate whether there were technique differences between national level male (n=6) and female sprint kayak paddlen (n=4) to indicate whether the same coaching strategies could be used for men and women. It was found that, despite different boat velocities, male and female paddlen were not very different in some important technique variables. It was concluded that, until distinct differences are found in technique between men and women, these groups could be coached the same way
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