Current state of Anabasis salsa pasture varieties in Karakalpak Ustyurt (Uzbekistan) due to Aral Sea drying

This article is devoted to the study of the current state of 2 pasture varieties of the biyurgun type: Anabasis salsa with the participation of Caroxylon orientale, Artemisia terrae-albae and A. kemrudica; Anabasis salsa with Caroxylon orientale and Artemisia terra-albae and Convolvulus fruticosus, Lycium ruthenicum, Anabasis brachiata, Nanophyton erinaceum, Nitraria schoberi, Malacocarpus crithmifolius and Xylosalsola chiwensis, with single Crambe edentula specimens distributed across the territory of Karakalpak Ustyurt (Uzbekistan) under the influence of Aral Sea drying. The Anabasis salsa pasture type occupies a larger area than that occupied by the other pasture types in Karakalpak Ustyurt (2 664 774 ha) and accounts for 36.4% of the total territory, which includes 9 pasture varieties. This type is common on takyr, loamy saline soils and, high-gypsum soils. The area of the studied pasture varieties, soil cover nature, projective cover percentage, landscape plant species, species placement, forage yield and recommended seasonality of use were determined. According to our observations the investigated pasture varieties are recommended for use as autumn-winter pastures

Safety assessment of shoe insoles treated with various biocidal compositions

The article deals with the study of the antimicrobial activity of shoe insoles treated with biocidal compositions . Antimicrobial treatment was carried out in distilled water using the following chemical agents: polyvinyl alcohol (PVA), salicylic acid (SA), copper sulfate, urea, polyvinylpyrrolidone (PVP), benzoic acid. The antimicrobial activity of the modified materials was determined against test cultures - E. coli and molds p.Penicillium. It was found that the studied samples of shoe insoles have a stable antibacterial effect - the growth inhibition zone is from 2 mm to 4 mm, but there is no fungal resistance

Influence of CYP2C9 and VKORC1 gene variants on warfarin response in Kazakhstani patients with left ventricular assist devices

Heart failure is a worldwide epidemic affecting approximately 23 million people globally and is a major burden for the healthcare system [1,2]. Despite advances in medical therapy, the disease is progressive and a significant proportion of patients will need advanced heart replacement therapy. Left ventricular assist devices (LVAD) are an invaluable part of the therapeutic measures for patients suffering from advanced heart failure. When used either as a bridge to transplant, to promote myocardial recovery, or as lifetime use, LVADs have proven to prolong survival and improve quality of life [1-3]. In spite of their success in improving mortality and quality of life, thrombotic and bleeding events remain significant complications [1]. Achieving therapeutic anticoagulation efficiently with warfarin is important to reduce thrombotic and bleeding risks and is influenced by genotype. Warfarin has a narrow therapeutic index and displays marked person-to-person variation in dose requirement. Functional polymorphisms at candidate genes can therefore offer utility as biomarkers to individualize warfarin treatment

Gene expression and methylation profiles as a biomarker for human radiation exposure

Taking into account the fact that Kazakhstan is one of the world's leaders in uranium mining, and given the extent of the damage suffered as a result of the work on the Semipalatinsk nuclear test site, the general background radiation in some regions came under the influence of additional effects of chronic exposure to low doses of radiation, the study and search for new methods of dosimetry, as an integral part of the radiological protection of the population, is a priority for the state. The purpose of this study is the search for and development of potential biomarkers by assessing the impact if ionising radiation on gene expression and quantification of global methylation and hydroxymethylation of uranium industry workers

Gene expression and methylation profiles as a biomarker for human radiation exposure

Taking into account the fact that Kazakhstan is one of the world's leaders in uranium mining, and given the extent of the damage suffered as a result of the work on the Semipalatinsk nuclear test site, the general background radiation in some regions came under the influence of additional effects of chronic exposure to low doses of radiation, the study and search for new methods of dosimetry, as an integral part of the radiological protection of the population, is a priority for the state. The purpose of this study is the search for and development of potential biomarkers by assessing the impact if ionising radiation on gene expression and quantification of global methylation and hydroxymethylation of uranium industry workers

Screening mutation in RYR2 gene in a Kazakhstani idiopathic ventricular tachycardia study cohort: two novel mutations

The human ryanodine receptor 2 (RYR2) is one of the key players tightly regulating calcium efflux from the sarcoplasmic reticulum to the cytosol and found frequently mutated (<60%) in context of catecholaminergic polymorphic ventricular tachycardia (CPVT1) [1]

The Ability of Quantum Dots Formation in Thin Nanostructured Amorphous Films

In the last years an interest in field of quantum dots devices creating has been increased. In this work the nanocrystallite with Frank-Kasper structure was examined as the quantum dot in amorphous film. An ability to create all-inorganic Quantum Dots Light Emission Device may be considered for Tb 30 Fe 70 , Co 80 C 20 , Fe 86 Mn 13 C and Co 50 Pd 50 films. The self-organisation of atomic structure in Tb 30 Fe 70 , Co 80 C 20 , Fe 86 Mn 13 C and Co 50 Pd 50 films, which possess large values of perpendicular magnetic anisotropy (PMA) constant (K ⊥ ~ 10 erg/cm ), were investigated by methods of electron diffraction and transmission electron microscopy, including the method of bend contours. The crystallization of the films proceeds in an explosive way forming different dissipative structures from initial nanocrystalline state. In previous works [2, 3] it was shown that after crystallization (Т ann ~ 260-330 °C) the atomic structures of Tb 30 Fe 70 , Co 80 C 20 , Fe 86 Mn 13 C and Co 50 Pd 50 films are tetrahedrally close-packed Frank-Kasper structures. In this work the structural model of thin film at mesoscale and its correlation with magnetic and optical properties is proposed.В последние годы большой интерес привлекают исследования, связанные с устройствами, работающими на квантовых точках. В данной статье нанокристаллиты со структурами Франка-Каспера исследованы как квантовые точки в аморфных пленках. Возможность создания эмиссионных устройств на полностью неорганических квантовых точках может быть рассмотрена для Co 80 C 20 , Tb 30 Fe 70 , Fe 86 Mn 13 C и Co 50 Pd 50 пленок. Самоорганизация атомнойструктуры Co 80 C 20 , Tb 30 Fe 70 , Fe 86 Mn 13 C и Co 50 Pd 50 в пленках, которые обладают высокими значениями константы, перпендикулярной магнитной анизотропии (ПМА) K ⊥ ~ 10 эрг/см , исследованы методами электронной дифракции и просвечивающей электронной микроскопии, включая метод изгибных контуров. Процессы взрывной кристаллизации аморфных пленок формируют различные диссипативные структуры из нанокристаллических зародышей. В предыдущих работах [2, 3] было показано, что после кристаллизации (Т отжига ~ 260-330 °C) атомная структура Tb 30 Fe 70 , Co 80 C 20 , Fe 86 Mn 13 C и Co 50 Pd 50 была определена как тетраэдрически плотно упакованная структура Франка Каспера. В этих работах структурные модели тонких пленок, созданные для микро-и мезомасштабов связываются с магнитными и оптическими свойствами пленок

Representation of phraseological units with a zoonym component in the German and English linguistic views of the world

Phraseological units with a zoonym component are the focus of the given scientific research. The relevance of this study arouses little doubt, since zoo-phraseologisms are widely used among native speakers, but a person for whom German and English are foreign languages uses these units in his speech extremely rarely, as they are difficult to perceive, and their misuse can lead to failures in intercultural communication. In addition, this layer of language is considered not fully explored. In this regard, it is necessary to conduct a more detailed study considering phraseological units with zoonims, the attempt is presented in the following article.The material of our research is the data of phraseological dictionaries of the German and English languages, stylistic and explanatory dictionaries, collections of commonly used proverbs in German and English.As methods of research, discursive analysis, functional analysis, various methods of descriptive and comparative method have served.The practical and theoretical significance of our research work is that the results of the study can be applied in the study of a foreign language for understanding the culture of native speakers