4,293 research outputs found
Características qualitativas da carcaça de cordeiros terminados em pastagem nativa da Caatinga, submetidos a diferentes suplementações de sal mineral.
Resumo: Objetivou-se determinar as características qualitativas da carcaça de cordeiros terminados em pastagem nativa da caatinga submetidos a diferentes suplementações de sal mineral. Foram utilizados 24 ovinos em terminação mestiços Santa Inês, distribuídos em um delineamento inteiramente casualizado, em três tratamentos, conforme as seguintes suplementações de sal mineral: sal mineral comercial (SALMINC), sal mineral comercial acrescido de 750 ppm de zinco animal-1 (SALMINCZn) e sal comercial com fornecimento de 2,5 ml por peso vivo metabólico (PV)0,75 animal-1 de propilenoglicol (SALMINCPeg), com oito repetições cada. Foram avaliadas as caracteristicas cor, área de olho de lombo/gabarito (cm2), área de olho de lombo/fórmula (cm2), espessura de gordura (mm), marmoreio da gordura (1-5), distribuição do marmoreio da gordura (1-3), textura da carne (1-5), textura da gordura (1-5). A única variável que diferiu entre os tratamentos avaliados foi a espessura de gordura (P<0,05). Os cordeiros que foram suplementados com sal mineral acrescido de 750 ppm de zinco apresentaram maior espessura de gordura. O uso de sal mineral com adição de Zinco influenciou na obtenção de uma maior espessura de gordura na carcaça de ovinos. [Qualitative carcass characteristics of lambs finished in native pasture of the Caatinga submitted to differents supplementations of mineral salt]. Abstract: The aim was to determine the qualitative characteristics of the carcass of lambs finished on native pasture of the Caatinga submitted to differents mineral salt supplementations. Were used 24 crossbred sheep Santa Ines in termination, distributed in a completely randomized design, with three treatments, according to the following supplements of mineral salt: commercial mineral salt (SALMINC), commercial mineral salt plus 750 ppm of zinc per animal-1 (SALMINCZn) and commercial mineral salt supply with 2.5 ml of propylene glycol per metabolic body weight (BW)0.75 animal-1 (SALMINCPeg), with eight replicates each. Were evaluated the characteristics of color, rib eye area/feedblack (cm2), rib eye area /formula (cm2), fat thickness (mm), marbling fat (1-5), distribution of marbling fat were evaluated (1-3), texture of meat (1-5), texture of fat (1-5). The only variable that differed among the treatments was the fat thickness (P <0.05). The lambs were supplemented with mineral salt plus zinc had greater fat thickness. The use of mineral salt added with zinc had influenced in getting of higher thickness carcass fat of sheep
Avaliação da biodistribuição de nanopartículas mucoadesivas em branqueas de tambaquis amazônicos.
Produtividade do Capim-Marandu sob diferentes doses de nitrogênio.
Objetivou-se com este trabalho avaliar o efeito de diferentes doses de nitrogênio (N) sobre o rendimento de matéria seca (MS) do capim Brachiaria brizantha cv. Marandu. O trabalho foi conduzido, no período de dezembro de 2011 a abril de 2012, no Campo Experimental da Embrapa Meio-Norte, localizado no município de Parnaíba, Piauí
What Can We Do When All Collapses? Fatal Outcome of Collapsing Glomerulopathy and Systemic Lupus Erythematosus With Diffuse Alveolar Hemorrhage: Case Report
NTRODUCTION:
Collapsing glomerulopathy (CG) is a rare form of glomerular injury. Although commonly associated with human immunodeficiency virus (HIV) infection, it can occur in association with systemic lupus erythematosus (SLE).
CASE REPORT:
We present the case of a 50-year-old man, with chronic kidney disease secondary to focal and segmental glomerulosclerosis, who received a cadaveric kidney transplant in 2007. There were no relevant intercurrences until May 2015, when he presented with nephrotic range proteinuria (± 4 g/d). A graft biopsy was performed and it did not show any significant pathological changes. In September, he developed a full nephrotic syndrome (proteinuria 19 g/d) and a graft biopsy was repeated. CG features were evident with a rich immunofluorescence. Antinuclear antibodies (ANA) and anti-double-stranded DNA (anti-dsDNA) antibodies were positive; the remaining immunologic study was normal. Viral markers for HIV, hepatitis C virus (HCV), and hepatitis B virus (HBV) were negative. The patient was treated with corticosteroid pulses and plasmapheresis (seven treatments). A rapid deterioration of kidney function was seen and he became dialysis dependent. He was discharged with a low-dose immunosuppressive treatment. In October, he was hospitalized with diffuse alveolar hemorrhage (DAH). The auto-immune study was repeated, revealing complement consumption and positive titers of ANA and Anti-dsDNA antibodies. Anti-neutrophil cytoplasmic antibodies (ANCAs) and antiglomerular basement membrane antibody (anti-GBM) were negative. Treatment with intravenous corticosteroids, plasmapheresis, and human immunoglobulin was ineffective and the outcome was fatal.
CONCLUSION:
This case report highlights the possible association of CG and SLE. To our knowledge, it is the first case of SLE presenting with CG and DAH, with the singularity of occurring in a kidney transplant recipient receiving immunosuppression.info:eu-repo/semantics/publishedVersio
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Personality and the creativity of frontline service employees: linear and curvilinear effects
Previous studies have investigated the relationship between the Five Factor model of personality and creativity. As this model has been criticised for providing a limited account of an individual’s personality, this study considers additional personality traits that have recently been investigated in the literature as determinants of employee behaviour. Moreover, we also contribute to the existing body of literature by conducting this study in a services setting, for which we predict personality traits will exert differentiated effects on creativity when compared to other settings. Finally, while past research has focused on linear effects, this study examines the existence of non-linear effects between personality and creativity. The results indicate that personality traits apart from the Five Factor model have an impact on creativity and that the effects of several personality traits on the creativity of frontline service employees differ from those obtained in other settings. Lastly, the findings also show that five of the personality traits have non-linear effects on creativity, and this may be a stimulus for a new stream of research in the human resources literature
First record of Neoechinorhynchus buttnerae and Piscinoodinium pillulare infection in Colossoma macropomum in the state of Tocantins, Brazil.
This study aims to report the occurrence of two important parasites in farmed tambaqui Colossoma macropomum in the state of Tocantins, the acanthocephalan Neoechinorhynchus buttnerae and the dinoflagellate protozoan Piscinoodinium pillulare, also suggesting the main treatments to control them. The fish sampled for the study were infected by N. buttnerae, and P. pillulare, with prevalence from 100% and mean intensity from 51.4 to 354,264, respectively. This was the first report on the occurrence of such parasites in C. macropomum in the state of Tocantins. We emphasize the need to adopt good farm management and biosecurity practices to prevent pathogenic agents to enter or leave a property. Reported treatments with synthetic and natural products with positive results are also suggested to treat against those parasites in farmed C. macropomum.Título em Português: Primeiro registro de infecção por Neoechinorhynchus buttnerae e Piscinoodinium pillulare em Colossoma macropomum no estado do Tocantins, Brasil
data from a Portuguese spondyloarthritis cohort
Background: Axial spondyloarthritis (axSpA), particularly ankylosing spondylitis was historically considered a male’s disease and has been under-recognized in women. Emerging evidence reveals sex differences in pathophysiology, disease presentation and therapeutic efficacy. Objective: To identify differences between sexes in a Portuguese cohort of patients with axSpA regarding clinical manifestations, disease activity, functional capacity, patient related outcomes and presence of sacroiliitis on x-ray or magnetic resonance imaging. Methods: Patients with ≥18 years fulfilling the ASAS-Assessment of Spondyloarthritis International Society classification criteria for axSpA registered in the electronic Rheumatic Diseases Portuguese Register (Reuma.pt) were included in this multicentric cross-sectional study. Sociodemographic data, clinical features and imaging were collected from the first record in Reuma.pt. These variables were compared between sexes using Mann-Whitney test and Chi-Square test. Variables with a significant association with variable sex were considered in the multiple variable analysis to adjust the sex effect on the outcome variables. Statistical analysis was performed with R version 4.0.2 and p<0.05 was considered statistically significant. Results: A total of 1995 patients were included, 1114 (55.9%) men and 881 (44.1%) women. Men had an earlier disease onset (25.1 vs 28.4, p<0.001), were younger at diagnosis (26.9 vs 30.4, p<0.001) and were more frequently smokers (32.1% vs 15.7%, p<0.001). Comparing to women, men had worse Bath Ankylosing Spondylitis Metrological Index scores (4.0 vs 3.4, p<0.001), higher levels of C-Reactive Protein (10.5 vs 6.9 mg/L, p<0.001) and were more often Human Leukocyte Antigen-B27 positive (67.8% vs 54%, p<0.001). In contrast, women more frequently had inflammatory bowel disease (8.8% vs 4.9%, p=0.004), higher levels of erythrocyte sedimentation rate (25.0 vs 21.0mm/h, p=0.003) and worse patient-related outcomes-Bath Ankylosing Spondylitis Disease Activity Index (5.7 vs 4.5, p<0.001), Patient Global Assessment (60.0 vs 50.0, p<0.001) and fatigue (6.2 vs 5.0, p<0.001). Discussion: In this large multicentric study from a Portuguese axSpA cohort, we confirmed sex differences in patients with axSpA. This work brings awareness to these differences, resulting in less underdiagnosis and misdiagnosis, optimizing treatment strategies, and improving outcomes in axSpApublishersversionpublishe
Maternal γδ T cells shape offspring pulmonary type 2 immunity in a microbiota-dependent manner.
Immune development is profoundly influenced by vertically transferred cues. However, little is known about how maternal innate-like lymphocytes regulate offspring immunity. Here, we show that mice born from γδ T cell-deficient (TCRδ-/-) dams display an increase in first-breath-induced inflammation, with a pulmonary milieu selectively enriched in type 2 cytokines and type 2-polarized immune cells, when compared with the progeny of γδ T cell-sufficient dams. Upon helminth infection, mice born from TCRδ-/- dams sustain an increased type 2 inflammatory response. This is independent of the genotype of the pups. Instead, the offspring of TCRδ-/- dams harbors a distinct intestinal microbiota, acquired during birth and fostering, and decreased levels of intestinal short-chain fatty acids (SCFAs), such as pentanoate and hexanoate. Importantly, exogenous SCFA supplementation inhibits type 2 innate lymphoid cell function and suppresses first-breath- and infection-induced inflammation. Taken together, our findings unravel a maternal γδ T cell-microbiota-SCFA axis regulating neonatal lung immunity
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