Origen y definición de la necedad, con anotaciones a algunas necedades de las que se usan.

“A menudo se reniega de los maestros supremos; se rebela uno contra ellos; se enumeran sus defectos; se los acusa de ser aburridos, de una obra demasiado extensa, de extravagancia, de mal gusto, al tiempo que se los saquea, engalanándose con plumas ajenas; pero en vano nos debatimos bajo su yugo. Todo se tiñe de sus colores; por doquier encontramos sus huellas; inventan palabras y nombres que van a enriquecer el vocabulario general de los pueblos; sus expresiones se convierten en proverbiales, sus personajes ficticios se truecan en personajes reales, que tienen herederos y linaje. Abren horizontes de donde brotan haces de luz; siembran ideas, gérmenes de otras mil; proporcionan motivos de inspiración, temas, estilos a todas las artes: sus obras son las minas o las entrañas del espíritu humano” (François de Chateaubriand: Memorias de ultratumba, libro XII, capítulo I, 1822).&nbsp

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Obras .... : Tomo Segundo

Contén: [Política de Dios y Govierno de Christo] ; [El Parnaso Español, Monte en dos Cumbres ... Nueve Musas Castellanas] ; [Las Tres Musas últimas Castellanas, Segunda Cumbre del Parnaso

[Obras Completas]

En vol. III consta M. Rivadeneyra como edito

[Las tres musas castellanas : Segunda cumbre del Parnaso Español]

Sign.: A-X>86<Port. con grab. xilGrab. xil. alegórica, en p. 3

Obras Posthumas y Vida de Don Francisco de Quevedo y Villegas : Parte Tercera

Marca tip. en portSign.: [calderón]\p8\s, A-S\p8\s, T\p2\s, [@]\p1\s, V\p2\s, X\p4\sError de pág., de p. 86 pasa a p. 97Port. con esc. xil.: "Padilla"Texto a dos colContiene: Providencia de Dios ; La incomprehensible disposicion de Dios en las felicidades y sucessos prosperos y adversos que los del mundo llaman bienes de fortun

Obras de D. Francisco de Quevedo y Villegas : Tomo II

Contén: Política de Dios y Gobierno de Christo ... Tomo III de sus Obras ; El Parnaso Español ... con las Nueve Musas Castellanas ... Tomo IV de sus Obras ; Las Tres Ultimas Musas Castellanas ... Tomo V de sus Obra